Table I.

Comparison of number of PNA+ germinal centers (GCs) within splenic follicles of C3−/− mice, WT littermates, and C3 BM chimeras either immunized or nonimmune

ImmunizedNonimmune
No.No. of folliclesNo. of GCsaNo.No. of folliclesNo. of GCsa
WT938 ± 12b24 ± 9534 ± 61.8 ± 0.9
C3−/−832 ± 114 ± 2428 ± 81.2 ± 0.5
C3 BM chimera841 ± 1126 ± 14338 ± 122.3 ± 1.2
  • a Number of GCs based on counting of splenic follicles stained with PNA.

  • b Mean ± SD.