Table I.

IL-6, IL-10, and IFN-γ secretion upon CD38-CD31 interactionsa

NoneUntransfectedCD31 Transfected
IL-6610 ± 72650 ± 68820 ± 151
IL-1044 ± 3352 ± 2488 ± 66
IFN-γ800 ± 3611100 ± 4021900 ± 370
  • a Purified T cells (1 × 106) were incubated for 24 h with murine fibroblasts and with human CD31. Culture supernatants were then harvested and interleukin production evaluated by immunoenzymatic techniques using commercial kits. Data are representative of three experiments.