Table I.

Effect of i.p. injections of PBS or IFN-γ on the growth of i.p. allografted Meth A tumor cells in IFN-γ −/−B6 mice

InjectionMeth A Cellsa (×10−8 cells/mouse)
PBS5.76, 5.12, 3.86, 1.784.13 ± 1.75b
IFN-γ0, 0, 0, 00
  • a On days 4, 6, and 8 after i.p. transplantation of Meth A cells (3 × 106 cells/mouse) into IFN-γ −/− mice, IFN-γ (Life Technologies; 10 μg (= 105 U) in 0.1 ml of PBS/mouse) or PBS (0.1 ml/mouse) was i.p. injected. On day 13 after transplantation, the number of Meth A cells in the peritoneal cavity was assessed.

  • b Mean ± SD (n = 4).