Table I.

Change of footpad thickness according to treatment

DayTreatmentThickness Change (mm; mean ± SD)pa
1mIgG0.51 ± 0.120
mutant/Fc0.27 ± 0.105< 0.01
CsA + mIgG0.59 ± 0.106NS
CsA+ mutant/Fc0.18 ± 0.173< 0.01
2mIgG0.56 ± 0.154
mutant/Fc0.19 ± 0.054< 0.01
CsA + mIgG0.40 ± 0.098< 0.05
CsA+ mutant/Fc0.09 ± 0.036< 0.01
3mIgG0.42 ± 0.171
mutant/Fc0.15 ± 0.042< 0.01
CsA + mIgG0.39 ± 0.125NS
CsA+ mutant/Fc0.03 ± 0.039< 0.01
  • a Comparing with mIgG-treated mice. NS, not significant; mIgG, mouse IgG; eight mice were included in each group.