Table III.

Inhibition of apoptosis by the cysteine protease inhibitor Z-VADa

StimulusPercent Apoptosis Following Stimulation
Absence of Z-VADPresence of Z-VAD
Media6.7 ± 1.35.9 ± 0.8
UV68.9 ± 9.111.3 ± 1.8
Gamma irradiation73.9 ± 5.512.7 ± 1.5
Anisomycin86.1 ± 5.98.3 ± 0.6
anti-Fas55.1 ± 0.97.6 ± 1.1
  • a Jurkat cells were stimulated in the presence or absence of 30 μM Z-VAD. The percentage of apoptotic cells was determined 16 h later.