Table I.

Distribution of polymorphism in the Iα1 regulatory gene in IgAN patients and controlsa

ControlPatientsTotal\E
Wild type382260
Mutant72126
Total454388
  • a Variations of genotype of the middle portion (from −455 to −108, Fig. 1) of Iαi regulatory gene were determined by PCR-SSCP in 43 patients and 45 controls. χ2 = 11.23, p = 0.0008 patients versus controls, odds ratio = 5.18, z = 3.1.