RT Journal Article
SR Electronic
T1 A Hemagglutination Test and a Specific Depolymerase for Studying Immunologic Paralysis in Mice
JF The Journal of Immunology
JO J. Immunol.
FD American Association of Immunologists
SP 358
OP 363
VO 96
IS 2
A1 Brooke, Marcus S.
YR 1966
UL http://www.jimmunol.org/content/96/2/358.abstract
AB The specificity of a hemagglutination test for detecting antibodies against the polysaccharide of type III Diplococcus pneumoniae (SIII) and the ability of a specific depolymerase to clear the SIII from the blood of mice are described. Mice injected with relatively large quantities of SIII are specifically prevented from responding to further immunogenic doses of that antigen. The response of different strains of mice injected with varying quantities of SIII is compared on the basis of the hemagglutination and challenge tests.