RT Journal Article
SR Electronic
T1 Heterogeneity of Immune Anti-A Antibody in Relation to Forssman Antigen
JF The Journal of Immunology
JO J. Immunol.
FD American Association of Immunologists
SP 304
OP 310
VO 96
IS 2
A1 Yokoyama, Mitsuo
A1 Fudenberg, H. H.
YR 1966
UL http://www.jimmunol.org/content/96/2/304.abstract
AB Guinea pig antigen, sheep red cells (type R), human group A1 red cells and soluble specific blood group substance A contain a similar A-like antigenic determinant. The A-like antigen of certain pig red cells (API) reacts with “immune” but not with “naturally occurring” anti-A antibody in human serum. Pig Ap red cells also absorb anti-sheep red cell hemolysin from human sera containing “immune” anti-A antibody, but not from those containing “naturally occurring” anti-A; furthermore, such cells do not absorb the anti-sheep red cell hemolysin present in immune rabbit serum. These results suggest that immune group O sera may contain an antibody specific against both A antigen and Forssman antigen.