RT Journal Article
SR Electronic
T1 Esterase, Peptidase, and the Enhancement of Guinea Pig Complement
JF The Journal of Immunology
JO J. Immunol.
FD American Association of Immunologists
SP 8
OP 11
VO 96
IS 1
A1 Amiraian, Kenneth
A1 Purcell, James D.
YR 1966
UL http://www.jimmunol.org/content/96/1/8.abstract
AB The complement-enhancing property of bovine carboxypeptidase A is lost when the enzyme is treated with acetylimidazole. Bovine carboxypeptidase B is as effective in enhancing guinea pig complement as carboxypeptidase A when used at five times the molar concentration as the latter. These data suggest that the peptidase, and not the esterase, activity of carboxypeptidase A is associated with the complement-enhancing property. Bovine procarboxypeptidase A, inert in immune hemolysis, will, when treated with trypsin, enhance guinea pig complement.