PT - JOURNAL ARTICLE AU - Amiraian, Kenneth AU - Purcell, James D. TI - Esterase, Peptidase, and the Enhancement of Guinea Pig Complement DP - 1966 Jan 01 TA - The Journal of Immunology PG - 8--11 VI - 96 IP - 1 4099 - http://www.jimmunol.org/content/96/1/8.short 4100 - http://www.jimmunol.org/content/96/1/8.full SO - J. Immunol.1966 Jan 01; 96 AB - The complement-enhancing property of bovine carboxypeptidase A is lost when the enzyme is treated with acetylimidazole. Bovine carboxypeptidase B is as effective in enhancing guinea pig complement as carboxypeptidase A when used at five times the molar concentration as the latter. These data suggest that the peptidase, and not the esterase, activity of carboxypeptidase A is associated with the complement-enhancing property. Bovine procarboxypeptidase A, inert in immune hemolysis, will, when treated with trypsin, enhance guinea pig complement.