RT Journal Article
SR Electronic
T1 Pathogenesis of Venezuelan Equine Encephalomyelitis Virus
JF The Journal of Immunology
JO J. Immunol.
FD American Association of Immunologists
SP 49
OP 58
VO 96
IS 1
A1 Kundin, William D.
YR 1966
UL http://www.jimmunol.org/content/96/1/49.abstract
AB The pathogenesis of an attenuated and an unattenuated strain of Venezuelan equine encephalomyelitis (VEE) virus was studied in young adult mice by means of infectivity titrations and fluorescent antibody staining. Tissue infectivity and viral lethality were generally similar in mice inoculated intracerebrally (i.c.) or subcutaneously (s.c.) with unattenuated virus and i.c. with attenuated virus. The tissues most involved were brain, salivary glands, inguinal nodes and spleen. Mice inoculated s.c. with attenuated VEE virus survived the infection. Little virus was found in the brain.