RT Journal Article
SR Electronic
T1 Identification of a unique receptor on a group A streptococcus for the Fc region of human IgG3.
JF The Journal of Immunology
JO J. Immunol.
FD American Association of Immunologists
SP 2670
OP 2673
VO 136
IS 7
A1 Yarnall, M
A1 Boyle, M D
YR 1986
UL http://www.jimmunol.org/content/136/7/2670.abstract
AB Receptors that bind to the Fc region of all four human IgG subclasses have been described on a number of strains of group A streptococci. In this study, we have demonstrated that these immunoglobulin binding properties are mediated by two distinct Fc receptors. The first receptor, with a Mr of approximately 56,000, binds to human IgG1, IgG2, and IgG4, but not to IgG3. A second receptor, with a Mr of approximately 38,000, binds exclusively to human immunoglobulins of the IgG3 subclass.