PT  - JOURNAL ARTICLE
AU  - Finberg, Robert
AU  - Greene, Mark I.
AU  - Benacerraf, Baruj
AU  - Burakoff, Steven J.
TI  - The Cytolytic T Lymphocyte Response to Trinitrophenyl-Modified Syngeneic Cells
DP  - 1979 Sep 01
TA  - The Journal of Immunology
PG  - 1205--1209
VI  - 123
IP  - 3
4099  - http://www.jimmunol.org/content/123/3/1205.short
4100  - http://www.jimmunol.org/content/123/3/1205.full
SO  - J. Immunol.1979 Sep 01; 123
AB  - Mice were primed subcutaneously with trinitrophenyl (TNP)-modified syngeneic spleen cells. Seven days later, spleen cells from these in vivo primed mice, or spleen cells from naive mice, were co-cultured with TNP-modified syngeneic cells. Spleen cells from the in vivo primed mice demonstrated augmented cytolytic T lymphocyte (CTL) activity. The spleens of these in vivo primed mice contained a population of radioresistant, antigen-specific, helper T cells. Specifically, spleen cells from these mice, after x-irradiation, were able to augment the in vitro CTL response of normal spleen cells to TNP-modified syngeneic cells.