PT - JOURNAL ARTICLE AU - Peck, Richard D. AU - Brown, Arthur AU - Wust, Carl J. TI - Preliminary Evidence for Cell-Mediated Immunity in Cross-Protection Among Group A Arboviruses DP - 1975 Feb 01 TA - The Journal of Immunology PG - 581--584 VI - 114 IP - 2 Part 1 4099 - http://www.jimmunol.org/content/114/2_Part_1/581.short 4100 - http://www.jimmunol.org/content/114/2_Part_1/581.full SO - J. Immunol.1975 Feb 01; 114 AB - Unfractionated and T cell-enriched populations from spleens of mice immunized with Sinbdis virus confer cross-protection against Semliki forest virus challenge in recipient mice. Both Group A viruses are serologically related, but not by tests for cross-neutralizing antibody. The protection in mice persisted for three consecutive cell passages in uninfected mice. The results suggest that cell-mediated immunity accounts for cross-protection.