PT  - JOURNAL ARTICLE
AU  - Schell, R.
AU  - Musher, D.
AU  - Jacobson, K.
AU  - Schwethelm, P.
TI  - Induction of Acquired Cellular Resistance Following Transfer of Thymus-Dependent Lymphocytes from Syphilitic Rabbits
DP  - 1975 Feb 01
TA  - The Journal of Immunology
PG  - 550--553
VI  - 114
IP  - 2 Part 1
4099  - http://www.jimmunol.org/content/114/2_Part_1/550.short
4100  - http://www.jimmunol.org/content/114/2_Part_1/550.full
SO  - J. Immunol.1975 Feb 01; 114
AB  - Syphilitic rabbits have previously been shown to resist challenge with Listeria monocytogenes. Thirty days after rabbits were infected with Treponema pallidum, transfer of 4 to 6 × 108 viable spleen cells along with T. pallidum conferred resistance to Listeria on normal recipients. Treatment of the spleen cells with anti-thymus serum and complement inhibited or abolished their ability to transfer resistance to Listeria. These results support the hypothesis that the ability of syphilitic rabbits to suppress the growth of Listeria reflects stimulation of cell-mediated immunity during active infection with T. pallidum.