PT  - JOURNAL ARTICLE
AU  - Gasser, David L.
AU  - Fischgrund, Terry
TI  - Genetic Control of the Immune Response in Mice. IV. Relationship Between Graft vs Host Reactivity and Possession of the High Tumor Genotypes A<sup>y</sup>a and A<sup>vy</sup>a
DP  - 1973 Jan 01
TA  - The Journal of Immunology
PG  - 305--308
VI  - 110
IP  - 1
4099  - http://www.jimmunol.org/content/110/1/305.short
4100  - http://www.jimmunol.org/content/110/1/305.full
SO  - J. Immunol.1973 Jan 01; 110
AB  - The graft vs host (GVH) reactivity of spleen cells from mice possessing the high tumor genotypes Aya and Avya was compared with the reactivity of spleen cells from histocompatible nonagouti animals. Spleen cells from YBR aa mice caused significantly greater GVH reactions than YBR Aya cells, and spleen cells from C57BL/6J aa donors were more reactive in GVH assays than cells from C57BL/6J Avya mice. These results suggest that reduced immune responsiveness may be involved in the tumor susceptibility of Aya and Avya mice.