PT  - JOURNAL ARTICLE
AU  - Stockman, Gail D.
AU  - Heim, Lyle R.
AU  - South, Mary Ann
AU  - Trentin, John J.
TI  - Differential Effects of Cyclophosphamide on the B and T Cell Compartments of Adult Mice
DP  - 1973 Jan 01
TA  - The Journal of Immunology
PG  - 277--282
VI  - 110
IP  - 1
4099  - http://www.jimmunol.org/content/110/1/277.short
4100  - http://www.jimmunol.org/content/110/1/277.full
SO  - J. Immunol.1973 Jan 01; 110
AB  - Adult mice were given a single sublethal dose of cyclophosphamide. Effects of the drug on the bone marrow-derived (B) and thymus-derived (T) cell compartments were measured by studies on lymphocyte transformation, lymphoid tissue morphology and responsiveness to a primary injection of keyhole limpet hemocyanin. These studies indicated that the effect of cyclophosphamide on the B cell compartment was more severe and longer-lasting than the effect on the T cell compartment.