PT - JOURNAL ARTICLE AU - Brunell, Philip A. AU - Granat, Miriam AU - Gershon, Anne A. TI - The Antigens of Varicella-Zoster Virus DP - 1972 Mar 01 TA - The Journal of Immunology PG - 731--737 VI - 108 IP - 3 4099 - http://www.jimmunol.org/content/108/3/731.short 4100 - http://www.jimmunol.org/content/108/3/731.full SO - J. Immunol.1972 Mar 01; 108 AB - Precipitin antigen was prepared from cultures infected with V-Z virus. Five separate antigens were identified. Reactions with radiolabeled antigen were detected by autoradiography. Partial purification of antigens could be accomplished in a discontinuous sucrose gradient, yet too little antigen was recovered from DEAE to make this a practicable purification method. Most of the antigenic activity was eluted from G-200 Sephadex. Antigens were identified by their degree of chemical stability. The α antigen was the only one which was stable at pH 3. The β antigen was destroyed by CsCl or DOC. DOC released the γ Δ, and ε antigens from the infectious viral particle.