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DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease

Melinda Czeh, Sina Stäble, Stephen Krämer, Lena Tepe, Sweta Talyan, Joana Carrelha, Yiran Meng, Barbara Heitplatz, Marius Schwabenland, Michael D. Milsom, Christoph Plass, Marco Prinz, Matthias Schlesner, Miguel A. Andrade-Navarro, Claus Nerlov, Sten Eirik W. Jacobsen, Daniel B. Lipka and Frank Rosenbauer
J Immunol December 13, 2021, ji2100624; DOI: https://doi.org/10.4049/jimmunol.2100624
Melinda Czeh
*Institute of Molecular Tumor Biology, University of Münster, Münster, Germany;
†MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK;
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Sina Stäble
‡Section Translational Cancer Epigenomics, Division of Translational Medical Oncology, German Cancer Research Center and National Center for Tumor Diseases Heidelberg, Heidelberg, Germany;
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  • ORCID record for Sina Stäble
Stephen Krämer
‡Section Translational Cancer Epigenomics, Division of Translational Medical Oncology, German Cancer Research Center and National Center for Tumor Diseases Heidelberg, Heidelberg, Germany;
§Biomedical Informatics, Data Mining and Data Analytics, Faculty of Applied Computer Science and Medical Faculty, University of Augsburg, Germany;
¶Bioinformatics and Omics Data Analysis, German Cancer Research Center, Heidelberg, Germany;
‖Faculty of Biosciences, Heidelberg University, Heidelberg, Germany;
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Lena Tepe
*Institute of Molecular Tumor Biology, University of Münster, Münster, Germany;
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Sweta Talyan
#Faculty of Biology, Johannes Gutenberg University of Mainz, Mainz, Germany;
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  • ORCID record for Sweta Talyan
Joana Carrelha
†MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK;
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Yiran Meng
†MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK;
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  • ORCID record for Yiran Meng
Barbara Heitplatz
**Gerhard-Domagk-Institute of Pathology, University Hospital Münster, University of Münster, Münster, Germany;
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Marius Schwabenland
††Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany;
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  • ORCID record for Marius Schwabenland
Michael D. Milsom
‡‡Division of Experimental Hematology, German Cancer Research Center, Heidelberg, Germany;
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Christoph Plass
§§Division of Cancer Epigenomics, German Cancer Research Center, Heidelberg, Germany;
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Marco Prinz
††Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany;
¶¶Centre for Biological Signalling Studies and Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany;
‖‖Center for Basics in NeuroModulation, Faculty of Medicine, University of Freiburg, Freiburg, Germany;
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Matthias Schlesner
§Biomedical Informatics, Data Mining and Data Analytics, Faculty of Applied Computer Science and Medical Faculty, University of Augsburg, Germany;
¶Bioinformatics and Omics Data Analysis, German Cancer Research Center, Heidelberg, Germany;
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Miguel A. Andrade-Navarro
#Faculty of Biology, Johannes Gutenberg University of Mainz, Mainz, Germany;
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Claus Nerlov
†MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK;
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Sten Eirik W. Jacobsen
†MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK;
##Department of Cell and Molecular Biology and Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden; and
***Karolinska University Hospital, Stockholm, Sweden
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Daniel B. Lipka
‡Section Translational Cancer Epigenomics, Division of Translational Medical Oncology, German Cancer Research Center and National Center for Tumor Diseases Heidelberg, Heidelberg, Germany;
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Frank Rosenbauer
*Institute of Molecular Tumor Biology, University of Münster, Münster, Germany;
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  • ORCID record for Frank Rosenbauer

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Print ISSN 0022-1767        Online ISSN 1550-6606