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4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages

Ciana Diskin, Alessia Zotta, Sarah E. Corcoran, Victoria J. Tyrrell, Zbigniew Zaslona, Valerie B. O’Donnell and Luke A. J. O’Neill
J Immunol October 11, 2021, ji2100488; DOI: https://doi.org/10.4049/jimmunol.2100488
Ciana Diskin
*School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; and
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  • ORCID record for Ciana Diskin
Alessia Zotta
*School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; and
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Sarah E. Corcoran
*School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; and
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Victoria J. Tyrrell
†Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, United Kingdom
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  • ORCID record for Victoria J. Tyrrell
Zbigniew Zaslona
*School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; and
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Valerie B. O’Donnell
†Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, United Kingdom
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Luke A. J. O’Neill
*School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; and
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Print ISSN 0022-1767        Online ISSN 1550-6606