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Mycobacterial Cord Factor Reprograms the Macrophage Response to IFN-γ towards Enhanced Inflammation yet Impaired Antigen Presentation and Expression of GBP1

Alexandra Huber, Barbara Killy, Nadine Grummel, Barbara Bodendorfer, Sushmita Paul, Veit Wiesmann, Elisabeth Naschberger, Jana Zimmer, Stefan Wirtz, Ulrike Schleicher, Julio Vera, Arif Bülent Ekici, Alexander Dalpke and Roland Lang
J Immunol August 12, 2020, ji2000337; DOI: https://doi.org/10.4049/jimmunol.2000337
Alexandra Huber
*Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Barbara Killy
*Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Nadine Grummel
*Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Barbara Bodendorfer
*Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Sushmita Paul
†Laboratory of Systems Tumor Immunology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Veit Wiesmann
‡Fraunhofer-Institut für Integrierte Schaltungen, D-91058 Erlangen, Germany;
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  • ORCID record for Veit Wiesmann
Elisabeth Naschberger
§Molekulare und Experimentelle Chirurgie, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, D-91054 Erlangen, Germany;
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Jana Zimmer
¶Department of Infectious Diseases, University Hospital Heidelberg, D-69120 Heidelberg, Germany;
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Stefan Wirtz
‖Medizinische Klinik 1, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Ulrike Schleicher
*Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Julio Vera
†Laboratory of Systems Tumor Immunology, University Hospital Erlangen and Friedrich-Alexander University Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Arif Bülent Ekici
#Institut für Humangenetik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany; and
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Alexander Dalpke
¶Department of Infectious Diseases, University Hospital Heidelberg, D-69120 Heidelberg, Germany;
**Institut für Medizinische Mikrobiologie und Hygiene, Technische Universität Dresden, 01307 Dresden, Germany
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Roland Lang
*Institut für Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany;
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Print ISSN 0022-1767        Online ISSN 1550-6606