mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a
Andrew J. Monteith, Heather A. Vincent, SunAh Kang, Patrick Li, Tauris M. Claiborne, Zenon Rajfur, Ken Jacobson, Nathaniel J. Moorman and Barbara J. Vilen
J Immunol June 4, 2018, ji1701712; DOI: https://doi.org/10.4049/jimmunol.1701712
Andrew J. Monteith
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
Heather A. Vincent
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
SunAh Kang
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
Patrick Li
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
Tauris M. Claiborne
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
Zenon Rajfur
†Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; and
‡Department of Physics, Astronomy, and Applied Computer Science, Institute of Physics, Jagiellonian University, 31-007 Krakow, Poland
Ken Jacobson
†Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; and
Nathaniel J. Moorman
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;
Barbara J. Vilen
*Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;