Novel Anti-Inflammatory Peptides Based on Chemokine–Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis
Emily F. McNaughton, Andrew D. Eustace, Sophie King, Richard B. Sessions, Alasdair Kay, Michele Farris, Robert Broadbridge, Oksana Kehoe, Andreas J. Kungl and Jim Middleton
J Immunol March 23, 2018, ji1701187; DOI: https://doi.org/10.4049/jimmunol.1701187
Emily F. McNaughton
*School of Oral and Dental Sciences, Faculty of Health Sciences, University of Bristol, Bristol BS1 2LY, United Kingdom;
Andrew D. Eustace
*School of Oral and Dental Sciences, Faculty of Health Sciences, University of Bristol, Bristol BS1 2LY, United Kingdom;
Sophie King
*School of Oral and Dental Sciences, Faculty of Health Sciences, University of Bristol, Bristol BS1 2LY, United Kingdom;
Richard B. Sessions
†School of Biochemistry, Faculty of Biomedical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom;
Alasdair Kay
‡Leopold Muller Arthritis Research Centre, Institute for Science and Technology in Medicine, Robert Jones and Agnes Hunt Orthopaedic Hospital, Medical School, Keele University, Keele SY10 7AG, United Kingdom;
Michele Farris
§Peptide Protein Research Ltd., Bishop's Waltham SO32 1QD, United Kingdom; and
Robert Broadbridge
§Peptide Protein Research Ltd., Bishop's Waltham SO32 1QD, United Kingdom; and
Oksana Kehoe
‡Leopold Muller Arthritis Research Centre, Institute for Science and Technology in Medicine, Robert Jones and Agnes Hunt Orthopaedic Hospital, Medical School, Keele University, Keele SY10 7AG, United Kingdom;
Andreas J. Kungl
¶Karl-Franzens University, Graz 8010, Austria
Jim Middleton
*School of Oral and Dental Sciences, Faculty of Health Sciences, University of Bristol, Bristol BS1 2LY, United Kingdom;