Published Ahead of Print

ALLERGY AND OTHER HYPERSENSITIVITIES

You have accessRestricted access
A Rapid Shift from Chronic Hyperoxia to Normoxia Induces Systemic Anaphylaxis via Transient Receptor Potential Ankyrin 1 Channels on Mast Cells
Kenshiro Matsuda, Peter D. Arkwright, Yasuo Mori, Masa-aki Oikawa, Ryo Muko, Akane Tanaka and Hiroshi Matsuda

J Immunol October 23, 2020, ji2000149; DOI: https://doi.org/10.4049/jimmunol.2000149

ANTIGEN RECOGNITION AND RESPONSES

You have accessRestricted access
Polyglutamine-Related Aggregates Can Serve as a Potent Antigen Source for Cross-Presentation by Dendritic Cells
Shira Tabachnick-Cherny, Sivan Pinto, Dikla Berko, Caterina Curato, Yochai Wolf, Ziv Porat, Rotem Karmona, Boaz Tirosh, Steffen Jung and Ami Navon

J Immunol October 16, 2020, ji1901535; DOI: https://doi.org/10.4049/jimmunol.1901535

AUTOIMMUNITY

You have accessRestricted access
Adenosine-to-Inosine RNA Editing of Alu Double-Stranded (ds)RNAs Is Markedly Decreased in Multiple Sclerosis and Unedited Alu dsRNAs Are Potent Activators of Proinflammatory Transcriptional Responses
John T. Tossberg, Rachel M. Heinrich, Virginia M. Farley, Philip S. Crooke III and Thomas M. Aune

J Immunol October 12, 2020, ji2000384; DOI: https://doi.org/10.4049/jimmunol.2000384
You have accessRestricted access
Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis
Marina A. Korn, Heike Schmitt, Sieglinde Angermüller, David Chambers, Michaela Seeling, Uwe T. Lux, Stefanie Brey, Dmytro Royzman, Christin Brückner, Vanessa Popp, Elena Percivalle, Tobias Bäuerle, Elisabeth Zinser, Thomas H. Winkler, Alexander Steinkasserer, Falk Nimmerjahn and Lars Nitschke

J Immunol October 5, 2020, ji2000472; DOI: https://doi.org/10.4049/jimmunol.2000472

BRIEF REVIEWS

You have accessRestricted access
Immune Response Resetting as a Novel Strategy to Overcome SARS-CoV-2–Induced Cytokine Storm
Alexandre E. Nowill and Pedro O. de Campos-Lima

J Immunol September 21, 2020, ji2000892; DOI: https://doi.org/10.4049/jimmunol.2000892

CLINICAL AND HUMAN IMMUNOLOGY

You have accessRestricted access
IL-7Rα^low CD8⁺ T Cells from Healthy Individuals Are Anergic with Defective Glycolysis
Ji Hyun Sim, Jin-Hee Kim, Ae Kyung Park, Jeeyun Lee, Kyoung-Mee Kim, Hyun Mu Shin, Minji Kim, Kyungho Choi, Eun Young Choi, Insoo Kang, Dong-Sup Lee and Hang-Rae Kim

J Immunol October 26, 2020, ji1901470; DOI: https://doi.org/10.4049/jimmunol.1901470
Open Access
Innate Immune Responses and Gut Microbiomes Distinguish HIV-Exposed from HIV-Unexposed Children in a Population-Specific Manner
Author Choice Article

Nelly Amenyogbe, Pedro Dimitriu, Patricia Cho, Candice Ruck, Edgardo S. Fortuno III, Bing Cai, Ariane Alimenti, Hélène C. F. Côté, Evelyn J. Maan, Amy L. Slogrove, Monika Esser, Arnaud Marchant, Tessa Goetghebuer, Casey P. Shannon, Scott J. Tebbutt, Tobias R. Kollmann, William W. Mohn and Kinga K. Smolen

J Immunol October 16, 2020, ji2000040; DOI: https://doi.org/10.4049/jimmunol.2000040
You have accessRestricted access
Effect of Ibrutinib on the IFN Response of Chronic Lymphocytic Leukemia Cells
Meihui Xia, Tina Yuxuan Luo, Yonghong Shi, Guizhi Wang, Hubert Tsui, Daniel Harari and David E. Spaner

J Immunol October 16, 2020, ji2000478; DOI: https://doi.org/10.4049/jimmunol.2000478

CUTTING EDGE

You have accessRestricted access
Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo
Douglas F. Pinheiro, Antal B. Szenes-Nagy, Megan M. Maurano, Melanie Lietzenmayer, Maria M. Klicznik, Raimund Holly, Daniel Kirchmeier, Sophie Kitzmueller, Gertrude Achatz-Straussberger, Michael D. Rosenblum, Josef Thalhamer, Abul K. Abbas and Iris K. Gratz

J Immunol October 9, 2020, ji1901094; DOI: https://doi.org/10.4049/jimmunol.1901094

IMMUNE REGULATION

You have accessRestricted access
Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4⁺ T Cells
Yan Zhou, Renping Zhao, Eva C. Schwarz, Rahmad Akbar, Mayis Kaba, Varsha Pattu, Volkhard Helms, Heiko Rieger, Paula Nunes-Hasler and Bin Qu

J Immunol October 26, 2020, ji2000195; DOI: https://doi.org/10.4049/jimmunol.2000195
You have accessRestricted access
Regulatory T Cells Maintain Selective Access to IL-2 and Immune Homeostasis despite Substantially Reduced CD25 Function
Erika T. Hayes, Cassidy E. Hagan, Liliane Khoryati, Marc A. Gavin and Daniel J. Campbell

J Immunol October 14, 2020, ji1901520; DOI: https://doi.org/10.4049/jimmunol.1901520
You have accessRestricted access
IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators
Marc Wehrli, Christoph Schneider, Fabiola Cortinas-Elizondo, Daniëlle Verschoor, Kayluz Frias Boligan, Olivia Joan Adams, Ruslan Hlushchuk, Christine Engelmann, Fritz Daudel, Peter M. Villiger, Frank Seibold, Nikhil Yawalkar, Cédric Vonarburg, Sylvia Miescher, Marius Lötscher, Thomas Kaufmann, Christian Münz, Christoph Mueller, Valentin Djonov, Hans-Uwe Simon and Stephan von Gunten

J Immunol October 2, 2020, ji1900883; DOI: https://doi.org/10.4049/jimmunol.1900883
You have accessRestricted access
Zbtb20 Restrains CD8 T Cell Immunometabolism and Restricts Memory Differentiation and Antitumor Immunity
Yanbo Sun, Nicholas K. Preiss, Kristine B. Valenteros, Yasmin Kamal, Young-Kwang Usherwood, H. Robert Frost and Edward J. Usherwood

J Immunol September 30, 2020, ji2000459; DOI: https://doi.org/10.4049/jimmunol.2000459

IMMUNE SYSTEM DEVELOPMENT

You have accessRestricted access
Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish
Zongfang Wei, Chenzheng Li, Yangping Zhang, Chenyu Lin, Yiyue Zhang, Liping Shu, Lingfei Luo, Jian Zhuo and Li Li

J Immunol October 19, 2020, ji2000473; DOI: https://doi.org/10.4049/jimmunol.2000473
You have accessRestricted access
Notch Regulates Innate Lymphoid Cell Plasticity during Human NK Cell Development
Ansel P. Nalin, Jesse J. Kowalski, Alexander C. Sprague, Blaire K. Schumacher, Adam G. Gerhardt, Youssef Youssef, Kiran V. Vedantam, Xiaoli Zhang, Christian W. Siebel, Emily M. Mace, Michael A. Caligiuri, Bethany L. Mundy-Bosse and Aharon G. Freud

J Immunol October 5, 2020, ji2000434; DOI: https://doi.org/10.4049/jimmunol.2000434

IMMUNOTHERAPY AND VACCINES

You have accessRestricted access
Vaccination with Intradermal Bacillus Calmette–Guérin Provides Robust Protection against Extrapulmonary Tuberculosis but Not Pulmonary Infection in Cynomolgus Macaques
Yusuke Tsujimura, Yumiko Shiogama, Shogo Soma, Tomotaka Okamura, Junichiro Takano, Emiko Urano, Yoshiko Murakata, Akira Kawano, Natsuko Yamakawa, Masamitsu N. Asaka, Kazuhiro Matsuo and Yasuhiro Yasutomi

J Immunol October 23, 2020, ji2000386; DOI: https://doi.org/10.4049/jimmunol.2000386
You have accessRestricted access
Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells
Esin Alpdundar Bulut, Banu Bayyurt Kocabas, Volkan Yazar, Gamze Aykut, Ulku Guler, Bekir Salih, Naz Surucu Yilmaz, Ihsan Cihan Ayanoglu, Muammer Merve Polat, Kamil Can Akcali, Ihsan Gursel and Mayda Gursel

J Immunol October 7, 2020, ji2000731; DOI: https://doi.org/10.4049/jimmunol.2000731

INFECTIOUS DISEASE AND HOST RESPONSE

You have accessRestricted access
Juvenile, but Not Adult, Mice Display Increased Myeloid Recruitment and Extracellular Matrix Remodeling during Respiratory Syncytial Virus Infection
Gerald G. Kellar, Stephen R. Reeves, Kaitlyn A. Barrow, Jason S. Debley, Thomas N. Wight and Steven F. Ziegler

J Immunol October 23, 2020, ji2000683; DOI: https://doi.org/10.4049/jimmunol.2000683
You have accessRestricted access
MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus
Xi Wang, Alayna K. Caffrey-Carr, Ko-wei Liu, Vanessa Espinosa, Walburga Croteau, Sourabh Dhingra, Amariliz Rivera, Robert A. Cramer and Joshua J. Obar

J Immunol October 21, 2020, ji2000802; DOI: https://doi.org/10.4049/jimmunol.2000802
You have accessRestricted access
IL-1α Is Essential for Oviduct Pathology during Genital Chlamydial Infection in Mice
Clare E. Gyorke, Avinash Kollipara, John Allen IV, Yugen Zhang, J. Ashley Ezzell, Toni Darville, Stephanie A. Montgomery and Uma M. Nagarajan

J Immunol October 21, 2020, ji2000600; DOI: https://doi.org/10.4049/jimmunol.2000600
You have accessRestricted access
Evaluation of IL-17D in Host Immunity to Group A Streptococcus Infection
Allen Washington Jr., Nissi Varki, J. Andrés Valderrama, Victor Nizet and Jack D. Bui

J Immunol October 19, 2020, ji1901482; DOI: https://doi.org/10.4049/jimmunol.1901482
You have accessRestricted access
The Immune System Fails to Mount a Protective Response to Gram-Positive or Gram-Negative Bacterial Prostatitis
Federico Lupo, Matthieu Rousseau, Tracy Canton and Molly A. Ingersoll

J Immunol October 14, 2020, ji2000587; DOI: https://doi.org/10.4049/jimmunol.2000587
You have accessRestricted access
Role of Tunneling Nanotube–like Structures during the Early Events of HIV Infection: Novel Features of Tissue Compartmentalization and Mechanism of HIV Spread
George Okafo, Silvana Valdebenito, Maribel Donoso, Ross Luu, David Ajasin, Brendan Prideaux, Santhi Gorantla and Eliseo A. Eugenin

J Immunol October 9, 2020, ji2000803; DOI: https://doi.org/10.4049/jimmunol.2000803
You have accessRestricted access
The Presence of Antibody-Dependent Cell Cytotoxicity–Mediating Antibodies in Kaposi Sarcoma–Associated Herpesvirus–Seropositive Individuals Does Not Correlate with Disease Pathogenesis or Progression
Lisa K. Poppe, Charles Wood and John T. West

J Immunol September 30, 2020, ji2000489; DOI: https://doi.org/10.4049/jimmunol.2000489
You have accessRestricted access
Airway Macrophages Mediate Mucosal Vaccine–Induced Trained Innate Immunity against Mycobacterium tuberculosis in Early Stages of Infection
Michael R. D’Agostino, Rocky Lai, Sam Afkhami, Amandeep Khera, Yushi Yao, Maryam Vaseghi-Shanjani, Anna Zganiacz, Mangalakumari Jeyanathan and Zhou Xing

J Immunol September 30, 2020, ji2000532; DOI: https://doi.org/10.4049/jimmunol.2000532
You have accessRestricted access
Discordance between Serum Neutralizing Antibody Titers and the Recovery from COVID-19
Merve Kalkan Yazıcı, Meliha Meric Koç, Nesibe Selma Çetin, Elif Karaaslan, Gulay Okay, Bulent Durdu, Bilge Sümbül and Mehmet Z. Doymaz

J Immunol September 25, 2020, ji2000840; DOI: https://doi.org/10.4049/jimmunol.2000840

INNATE IMMUNITY AND INFLAMMATION

Open Access
An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes
Author Choice Article

Alfredo A. Hernandez, Greg A. Foster, Stephanie R. Soderberg, Andrea Fernandez, Mack B. Reynolds, Mable K. Orser, Keith A. Bailey, Jason H. Rogers, Gagan D. Singh, Huaizhu Wu, Anthony G. Passerini and Scott I. Simon

J Immunol October 14, 2020, ji2000485; DOI: https://doi.org/10.4049/jimmunol.2000485
You have accessRestricted access
Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis
Elisa B. Prestes, Letícia S. Alves, Danielle A. S. Rodrigues, Fabianno F. Dutra, Patricia L. Fernandez, Claudia N. Paiva, Jonathan C. Kagan and Marcelo T. Bozza

J Immunol October 9, 2020, ji1900886; DOI: https://doi.org/10.4049/jimmunol.1900886
You have accessRestricted access
Absence of the C5a Receptor C5aR2 Worsens Ischemic Tissue Injury by Increasing C5aR1-Mediated Neutrophil Infiltration
Mike C. L. Wu, John D. Lee, Marc J. Ruitenberg and Trent M. Woodruff

J Immunol October 7, 2020, ji2000778; DOI: https://doi.org/10.4049/jimmunol.2000778
You have accessRestricted access
Inflammation Unrestrained by SIRPα Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-γ
Koby Kidder, Zhen Bian, Lei Shi and Yuan Liu

J Immunol October 7, 2020, ji2000652; DOI: https://doi.org/10.4049/jimmunol.2000652
You have accessRestricted access
Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid
Hilde Brouwers, Hulda S. Jónasdóttir, Marije E. Kuipers, Joanneke C. Kwekkeboom, Jennifer L. Auger, Mayra Gonzalez-Torres, Cristina López-Vicario, Joan Clària, Jona Freysdottir, Ingibjorg Hardardottir, José Garrido-Mesa, Lucy V. Norling, Mauro Perretti, Tom W. J. Huizinga, Margreet Kloppenburg, René E. M. Toes, Bryce Binstadt, Martin Giera and Andreea Ioan-Facsinay

J Immunol October 2, 2020, ji1801653; DOI: https://doi.org/10.4049/jimmunol.1801653
You have accessRestricted access
Non–Cell-Autonomous Activity of the Hemidesmosomal Protein BP180/Collagen XVII in Granulopoiesis in Humanized NC16A Mice
Lin Lin, Bin-Jin Hwang, Ning Li, Paul Googe, Luis A. Diaz, Ed Miao, Barbara Vilen, Nancy E. Thomas, Jenny Ting and Zhi Liu

J Immunol September 30, 2020, ji2000784; DOI: https://doi.org/10.4049/jimmunol.2000784
You have accessRestricted access
RIPK3 Promotes Mefv Expression and Pyrin Inflammasome Activation via Modulation of mTOR Signaling
Deepika Sharma, Ankit Malik, Arjun Balakrishnan, R. K. Subbarao Malireddi and Thirumala-Devi Kanneganti

J Immunol September 28, 2020, ji2000244; DOI: https://doi.org/10.4049/jimmunol.2000244

MOLECULAR AND STRUCTURAL IMMUNOLOGY

You have accessRestricted access
V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor
Sofia Rossini, Rémi Noé, Victoria Daventure, Maxime Lecerf, Sune Justesen and Jordan D. Dimitrov

J Immunol October 19, 2020, ji2000732; DOI: https://doi.org/10.4049/jimmunol.2000732
Open Access
Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues
Author Choice Article

Paula Ruibal, Kees L. M. C. Franken, Krista E. van Meijgaarden, Joeri J. F. van Loon, Dirk van der Steen, Mirjam H. M. Heemskerk, Tom H. M. Ottenhoff and Simone A. Joosten

J Immunol October 5, 2020, ji2000810; DOI: https://doi.org/10.4049/jimmunol.2000810

MUCOSAL IMMUNOLOGY

You have accessRestricted access
The GM-CSF Released by Airway Epithelial Cells Orchestrates the Mucosal Adjuvant Activity of Flagellin
Aneesh Vijayan, Laurye Van Maele, Delphine Fougeron, Delphine Cayet and Jean-Claude Sirard

J Immunol October 2, 2020, ji2000746; DOI: https://doi.org/10.4049/jimmunol.2000746

TUMOR IMMUNOLOGY

You have accessRestricted access
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating T_H1/T_H17 Cell Response
Feng-Shuang Yi, Xin Zhang, Kan Zhai, Zhong-Yin Huang, Xiu-Zhi Wu, Min-Ting Wu, Xin-Yu Shi, Xue-Bin Pei, Shu-Feng Dong, Wen Wang, Yuan Yang, Juan Du, Zeng-Tao Luo and Huan-Zhong Shi

J Immunol October 23, 2020, ji2000307; DOI: https://doi.org/10.4049/jimmunol.2000307
You have accessRestricted access
MARCH Proteins Mediate Responses to Antitumor Antibodies
Jailal N. Ablack, Jesus Ortiz, Jeevisha Bajaj, Kathleen Trinh, Frederic Lagarrigue, Joseph M. Cantor, Tannishtha Reya and Mark H. Ginsberg

J Immunol October 19, 2020, ji1901245; DOI: https://doi.org/10.4049/jimmunol.1901245
You have accessRestricted access
Combination of Fruquintinib and Anti–PD-1 for the Treatment of Colorectal Cancer
Yuanyuan Wang, Bin Wei, Jianhua Gao, Xiaomin Cai, Lingyan Xu, Haiqing Zhong, Binglin Wang, Yang Sun, Wenjie Guo, Qiang Xu and Yanhong Gu

J Immunol October 7, 2020, ji2000463; DOI: https://doi.org/10.4049/jimmunol.2000463
You have accessRestricted access
Intratumoral Activation of 41BB Costimulatory Signals Enhances CD8 T Cell Expansion and Modulates Tumor-Infiltrating Myeloid Cells
Patrick Innamarato, Sarah Asby, Jennifer Morse, Amy Mackay, MacLean Hall, Scott Kidd, Luz Nagle, Amod A. Sarnaik and Shari Pilon-Thomas

J Immunol October 5, 2020, ji2000759; DOI: https://doi.org/10.4049/jimmunol.2000759
You have accessRestricted access
Mouse 4T1 Breast Cancer Cell–Derived Exosomes Induce Proinflammatory Cytokine Production in Macrophages via miR-183
Jian Guo, Zhaojun Duan, Chen Zhang, Wei Wang, Huiwen He, Yan Liu, Peng Wu, Shengnan Wang, Mingcheng Song, Huilin Chen, Chong Chen, Qin Si, Rong Xiang and Yunping Luo

J Immunol September 28, 2020, ji1901104; DOI: https://doi.org/10.4049/jimmunol.1901104

Main menu

User menu

Search

Published Ahead of Print

ALLERGY AND OTHER HYPERSENSITIVITIES

ANTIGEN RECOGNITION AND RESPONSES

AUTOIMMUNITY

BRIEF REVIEWS

CLINICAL AND HUMAN IMMUNOLOGY

CUTTING EDGE

IMMUNE REGULATION

IMMUNE SYSTEM DEVELOPMENT

IMMUNOTHERAPY AND VACCINES

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

MUCOSAL IMMUNOLOGY

TUMOR IMMUNOLOGY

Navigate

For Authors

General Information

Journal Services