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ALLERGY AND OTHER HYPERSENSITIVITIES

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PRMT1 Modulates Processing of Asthma-Related Primary MicroRNAs (Pri-miRNAs) into Mature miRNAs in Lung Epithelial Cells
Weiqi Zhai, Haoming Sun, Zhi Li, Li Li, Ai Jin, Yuwen Li, Jian Chen, Xiaojun Yang, Qingzhu Sun, Shemin Lu and Michael Roth

J Immunol November 25, 2020, ji2000887; DOI: https://doi.org/10.4049/jimmunol.2000887

AUTOIMMUNITY

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T–B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein
Rachel H. Bonami, Lindsay E. Nyhoff, Dudley H. McNitt, Chrys Hulbert, Jamie L. Felton, Peggy L. Kendall and James W. Thomas

J Immunol November 16, 2020, ji1900464; DOI: https://doi.org/10.4049/jimmunol.1900464
Open Access
Screening of a Panel of Low Molecular Weight Compounds That Inhibit Synovial Fibroblast Invasion in Rheumatoid Arthritis
Author Choice Article

Tomoko Sugiura, Hiroki Kamino, Yuko Nariai, Yohko Murakawa, Masahiro Kondo, Makoto Kawakami, Noboru Ikeda, Yuji Uchio and Takeshi Urano

J Immunol November 11, 2020, ji1901429; DOI: https://doi.org/10.4049/jimmunol.1901429
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T Follicular Regulatory Cell–Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity
Waradon Sungnak, Allon Wagner, Monika S. Kowalczyk, Lloyd Bod, Yoon-Chul Kye, Peter T. Sage, Arlene H. Sharpe, Raymond A. Sobel, Francisco J. Quintana, Orit Rozenblatt-Rosen, Aviv Regev, Chao Wang, Nir Yosef and Vijay K. Kuchroo

J Immunol November 9, 2020, ji2000748; DOI: https://doi.org/10.4049/jimmunol.2000748

CLINICAL AND HUMAN IMMUNOLOGY

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A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients
Monty B. Mazer, Charles Caldwell, Jodi Hanson, Daniel Mannion, Isaiah R. Turnbull, Anne Drewry, Dale Osborne, Andrew Walton, Tessa Blood, Lyle L. Moldawer, Scott Brakenridge, Kenneth E. Remy and Richard S. Hotchkiss

J Immunol November 25, 2020, ji2001088; DOI: https://doi.org/10.4049/jimmunol.2001088
Open Access
Systematic Examination of Antigen-Specific Recall T Cell Responses to SARS-CoV-2 versus Influenza Virus Reveals a Distinct Inflammatory Profile
Author Choice Article

Jaclyn C. Law, Wan Hon Koh, Patrick Budylowski, Jonah Lin, FengYun Yue, Kento T. Abe, Bhavisha Rathod, Melanie Girard, Zhijie Li, James M. Rini, Samira Mubareka, Allison McGeer, Adrienne K. Chan, Anne-Claude Gingras, Tania H. Watts and Mario A. Ostrowski

J Immunol November 18, 2020, ji2001067; DOI: https://doi.org/10.4049/jimmunol.2001067
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A Sequential Two-Step Cell-Based Assay Predicts Immunosuppression-Related Adverse Events
François Bouchard-Boivin, Olivier Désy, Stéphanie Béland, Alcino Gama, Isabelle Lapointe, Julie Lesage, Isabelle Côté, Narcisse Singbo, Isabelle Houde and Sacha A. De Serres

J Immunol November 13, 2020, ji2000782; DOI: https://doi.org/10.4049/jimmunol.2000782

CORRECTIONS

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Correction: Antibodies against Phosphorylcholine and Malondialdehyde during the First Two Years of Life
Divya Thiagarajan, Susanna L. Lundström, Göran Pershagen, Catarina Almqvist, Ellika Andolf, Anna Hedman, Oscar Berg, Nina Oparina and Johan Frostegård

J Immunol November 25, 2020, ji2001224; DOI: https://doi.org/10.4049/jimmunol.2001224

IMMUNE REGULATION

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Foxo1 Serine 209 Is a Critical Regulatory Site of CD8 T Cell Differentiation and Survival
Leonard Benjamin Hills, Leena Abdullah, Hannah E. Lust, Hanna Degefu and Yina H. Huang

J Immunol November 23, 2020, ji2000216; DOI: https://doi.org/10.4049/jimmunol.2000216
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GEF-H1 Is Required for Colchicine Inhibition of Neutrophil Rolling and Recruitment in Mouse Models of Gout
Noah Fine, Eric Gracey, Ioannis Dimitriou, José La Rose, Michael Glogauer and Robert Rottapel

J Immunol November 16, 2020, ji1900783; DOI: https://doi.org/10.4049/jimmunol.1900783
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The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation
Mohammad Kamran, Jinyi Liang, Bing Liu, Yapeng Li, Junfeng Gao, Ashley Keating, Fathia Mohamed, Shaodong Dai, Richard Reinhardt, Yang Jiong, Zhongdao Wu and Hua Huang

J Immunol November 13, 2020, ji2000985; DOI: https://doi.org/10.4049/jimmunol.2000985

IMMUNOGENETICS

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Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses
Michael W. Grunst, Andres G. Grandea III, Sanath Kumar Janaka, Iman Hammad, Parker Grimes, Julie A. Karl, Roger Wiseman, David H. O’Connor and David T. Evans

J Immunol November 18, 2020, ji2000501; DOI: https://doi.org/10.4049/jimmunol.2000501

IMMUNOTHERAPY AND VACCINES

Open Access
TL1A–DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1–Specific T Cell Responses
Author Choice Article

Bruna Oriol-Tordera, Alex Olvera, Clara Duran-Castells, Anuska Llano, Beatriz Mothe, Marta Massanella, Judith Dalmau, Carmela Ganoza, Jorge Sanchez, Maria Luz Calle, Bonaventura Clotet, Javier Martinez-Picado, Eugènia Negredo, Julià Blanco, Dennis Hartigan-O'Connor, Christian Brander and Marta Ruiz-Riol

J Immunol November 11, 2020, ji2000933; DOI: https://doi.org/10.4049/jimmunol.2000933
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Essential Role of Neutrophils in the Protective Immune Response Induced by a Live Attenuated Leishmania Vaccine
Parna Bhattacharya, Ranadhir Dey, Ankit Saxena, Subir Karmakar, Nevien Ismail, Sreenivas Gannavaram, Pradeep K. Dagur, Monika Satoskar, Sanika Satoskar, Silvia De Paoli, Kazuyo Takeda, John Philip McCoy Jr. and Hira L. Nakhasi

J Immunol November 11, 2020, ji2000829; DOI: https://doi.org/10.4049/jimmunol.2000829

INFECTIOUS DISEASE AND HOST RESPONSE

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IL-4 Treatment Mitigates Experimental Cerebral Malaria by Reducing Parasitemia, Dampening Inflammation, and Lessening the Cytotoxicity of T Cells
Xianzhu Wu, Ramesh P. Thylur, Kiran K. Dayanand, Kishore Punnath, Christopher C. Norbury and D. Channe Gowda

J Immunol November 25, 2020, ji2000779; DOI: https://doi.org/10.4049/jimmunol.2000779
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IRF3 Signaling within the Mouse Stroma Influences Sepsis Pathogenesis
Erica L. Heipertz, Jourdan Harper, Dinesh G. Goswami, Charlie A. Lopez, Jose Nellikappallil, Ruben Zamora, Yoram Vodovotz and Wendy E. Walker

J Immunol November 25, 2020, ji1900217; DOI: https://doi.org/10.4049/jimmunol.1900217
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The Invariant NKT Cell Response Has Differential Signaling Requirements during Antigen-Dependent and Antigen-Independent Activation
Courtney K. Anderson, Shanelle P. Reilly and Laurent Brossay

J Immunol November 23, 2020, ji2000870; DOI: https://doi.org/10.4049/jimmunol.2000870
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SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals
Cecilie Bo Hansen, Ida Jarlhelt, Laura Pérez-Alós, Lone Hummelshøj Landsy, Mette Loftager, Anne Rosbjerg, Charlotte Helgstrand, Jais Rose Bjelke, Thomas Egebjerg, Joseph G. Jardine, Charlotte Sværke Jørgensen, Kasper Iversen, Rafael Bayarri-Olmos, Peter Garred and Mikkel-Ole Skjoedt

J Immunol November 18, 2020, ji2000898; DOI: https://doi.org/10.4049/jimmunol.2000898
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Control of B Cell Lymphoma by Gammaherpesvirus-Induced Memory CD8 T Cells
Nicholas K. Preiss, Taewook Kang, Young-Kwang Usherwood, Yina H. Huang, Bruce R. Branchini and Edward J. Usherwood

J Immunol November 13, 2020, ji2000734; DOI: https://doi.org/10.4049/jimmunol.2000734
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Innate Immune Memory to Repeated Borrelia burgdorferi Exposure Correlates with Murine In Vivo Inflammatory Phenotypes
Quentin Bernard and Linden T. Hu

J Immunol November 9, 2020, ji2000686; DOI: https://doi.org/10.4049/jimmunol.2000686
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CD28 Agonism Improves Survival in Immunologically Experienced Septic Mice via IL-10 Released by Foxp3⁺ Regulatory T Cells
Yini Sun, Jianfeng Xie, Jerome C. Anyalebechi, Ching-wen Chen, He Sun, Ming Xue, Zhe Liang, Kristen N. Morrow, Craig M. Coopersmith and Mandy L. Ford

J Immunol November 6, 2020, ji2000595; DOI: https://doi.org/10.4049/jimmunol.2000595

INNATE IMMUNITY AND INFLAMMATION

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Deficiency of the Intramembrane Protease SPPL2a Alters Antimycobacterial Cytokine Responses of Dendritic Cells
Ann-Christine Gradtke, Torben Mentrup, Christian H. K. Lehmann, Florencia Cabrera-Cabrera, Christine Desel, Darian Okakpu, Maike Assmann, Alexander Dalpke, Ulrich E. Schaible, Diana Dudziak and Bernd Schröder

J Immunol November 25, 2020, ji2000151; DOI: https://doi.org/10.4049/jimmunol.2000151
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NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense
Saeko Aoyama-Ishiwatari, Tomohiko Okazaki, Shun-ichiro Iemura, Tohru Natsume, Yasushi Okada and Yukiko Gotoh

J Immunol November 20, 2020, ji2000306; DOI: https://doi.org/10.4049/jimmunol.2000306
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Mannose-Binding Lectin Possesses Agglutination Activity and Promotes Opsonophagocytosis of Macrophages with Calreticulin Interaction in an Early Vertebrate
Liangliang Mu, Xiaoxue Yin, Hairong Wu, Yang Lei, Kailiang Han, Jinfeng Mo, Zheng Guo, Jun Li and Jianmin Ye

J Immunol November 16, 2020, ji2000256; DOI: https://doi.org/10.4049/jimmunol.2000256
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Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS
Yu-Lin Yao, Dandan Yu, Ling Xu, Tianle Gu, Yu Li, Xiao Zheng, Rui Bi and Yong-Gang Yao

J Immunol November 13, 2020, ji2000740; DOI: https://doi.org/10.4049/jimmunol.2000740
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IL-18 Responsiveness Defines Limitations in Immune Help for Specialized FcRγ^– NK Cells
Renee R. Anderko, Charles R. Rinaldo and Robbie B. Mailliard

J Immunol November 13, 2020, ji2000430; DOI: https://doi.org/10.4049/jimmunol.2000430
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IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming
Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, Sebastiaan A. J. Zaat, Michel van Weeghel, Dominique L. P. Baeten, Riekelt H. Houtkooper, Bart Everts, Gestur Vidarsson and Jeroen den Dunnen

J Immunol November 13, 2020, ji2000263; DOI: https://doi.org/10.4049/jimmunol.2000263
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NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor
Boyue Sun, Haoyang Zeng, Jiaqian Liang, Lele Zhang, Haiyang Hu, Quanyi Wang, Wei Meng, Chenhui Li, Fuqiang Ye, Chen Wang and Juanjuan Zhu

J Immunol November 11, 2020, ji1901455; DOI: https://doi.org/10.4049/jimmunol.1901455
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Overexpression of Macrophage-Inducible C-Type Lectin Mincle Aggravates Proinflammatory Responses to Streptococcus pneumoniae with Fatal Outcome in Mice
Femke D. Hollwedel, Regina Maus, Jennifer Stolper, Ayesha Khan, Bridget L. Stocker, Mattie S. M. Timmer, Xiuyuan Lu, Andreas Pich, Tobias Welte, Sho Yamasaki and Ulrich A. Maus

J Immunol November 6, 2020, ji2000509; DOI: https://doi.org/10.4049/jimmunol.2000509

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Glycine 236 in the Lower Hinge Region of Human IgG1 Differentiates FcγR from Complement Effector Function
Maximilian Brinkhaus, Ruben G. J. Douwes, Arthur E. H. Bentlage, A. Robin Temming, Steven W. de Taeye, Matthias Tammes Buirs, Jacoline Gerritsen, Juk Yee Mok, Giso Brasser, Peter C. Ligthart, Wim J. E. van Esch, Peter Verheesen, Hans de Haard, Theo Rispens and Gestur Vidarsson

J Immunol November 13, 2020, ji2000961; DOI: https://doi.org/10.4049/jimmunol.2000961

NOVEL IMMUNOLOGICAL METHODS

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Multibatch Cytometry Data Integration for Optimal Immunophenotyping
Masato Ogishi, Rui Yang, Conor Gruber, Peng Zhang, Simon J. Pelham, András N. Spaan, Jérémie Rosain, Marwa Chbihi, Ji Eun Han, V. Koneti Rao, Leena Kainulainen, Jacinta Bustamante, Bertrand Boisson, Dusan Bogunovic, Stéphanie Boisson-Dupuis and Jean-Laurent Casanova

J Immunol November 23, 2020, ji2000854; DOI: https://doi.org/10.4049/jimmunol.2000854
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Development of a SARS-CoV-2 Total Antibody Assay and the Dynamics of Antibody Response over Time in Hospitalized and Nonhospitalized Patients with COVID-19
Erik H. Vogelzang, Floris C. Loeff, Ninotska I. L. Derksen, Simone Kruithof, Pleuni Ooijevaar-de Heer, Gerard van Mierlo, Federica Linty, Juk Yee Mok, Wim van Esch, Sanne de Bruin, Alexander P. J. Vlaar, Bart Seppen, Maureen Leeuw, Anne J. G. van Oudheusden, Anton G. M. Buiting, Kin Ki Jim, Hans Vrielink, Francis Swaneveld, Gestur Vidarsson, C. Ellen van der Schoot, Peter C. Wever, Wentao Li, Frank van Kuppeveld, Jean-Luc Murk, Berend Jan Bosch, Gerrit-Jan Wolbink and Theo Rispens

J Immunol October 30, 2020, ji2000767; DOI: https://doi.org/10.4049/jimmunol.2000767

SYSTEMS IMMUNOLOGY

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Position-Dependent Differential Targeting of Somatic Hypermutation
Julian Q. Zhou and Steven H. Kleinstein

J Immunol November 13, 2020, ji2000496; DOI: https://doi.org/10.4049/jimmunol.2000496

TRANSPLANTATION

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Kras-Deficient T Cells Attenuate Graft-versus-Host Disease but Retain Graft-versus-Leukemia Activity
Lan Luo, Yuhong Chen, Xiao Chen, Yongwei Zheng, Vivian Zhou, Mei Yu, Robert Burns, Wen Zhu, Guoping Fu, Juan C. Felix, Christopher Hartley, Alisa Damnernsawad, Jing Zhang, Renren Wen, Williams R. Drobyski, Chunji Gao and Demin Wang

J Immunol November 6, 2020, ji2000006; DOI: https://doi.org/10.4049/jimmunol.2000006

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