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The Journal of Immunology

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Published Ahead of Print

AUTOIMMUNITY

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    Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells
    Jennifer R. Dwyer, Jeremy J. Racine, Harold D. Chapman, Anna Quinlan, Maximiliano Presa, Grace A. Stafford, Ingo Schmitz and David V. Serreze
    J Immunol June 27, 2022, ji2100558; DOI: https://doi.org/10.4049/jimmunol.2100558
  • You have accessRestricted access
    Analysis of Gene Expression and TCR/B Cell Receptor Profiling of Immune Cells in Primary Sjögren’s Syndrome by Single-Cell Sequencing
    Xianliang Hou, Xiaoping Hong, Minglin Ou, Shuhui Meng, Tingting Wang, Shengyou Liao, Jingquan He, Haiyan Yu, Lixiong Liu, Lianghong Yin, Dongzhou Liu, Donge Tang and Yong Dai
    J Immunol June 22, 2022, ji2100803; DOI: https://doi.org/10.4049/jimmunol.2100803

CLINICAL AND HUMAN IMMUNOLOGY

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    Comparison of Neutralizing Antibody Response Kinetics in Patients with Hand, Foot, and Mouth Disease Caused by Coxsackievirus A16 or Enterovirus A71: A Longitudinal Cohort Study of Chinese Children, 2017–2019
    Yonghong Zhou, Jiaxin Zhou, Jianli Yang, Qi Qiu, Lili Wang, Junmei Yang, Yu Li, Lu Liang, Peng Cui, Yibing Cheng, Wen Zheng, Huilin Shi, Hui Gong, Kai Wang, Chongchen Zhou, Justin Jang Hann Chu and Hongjie Yu
    J Immunol July 1, 2022, ji2200143; DOI: https://doi.org/10.4049/jimmunol.2200143
  • Open Access
    Characterization of Mycobacterium tuberculosis–Specific Th22 Cells and the Effect of Tuberculosis Disease and HIV Coinfection

    Author Choice Article

    Mohau S. Makatsa, F. Millicent A. Omondi, Rubina Bunjun, Robert J. Wilkinson, Catherine Riou and Wendy A. Burgers
    J Immunol July 1, 2022, ji2200140; DOI: https://doi.org/10.4049/jimmunol.2200140
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    Monitoring Circulating CD207+CD1a+ Cells in Langerhans Cell Histiocytosis and Clinical Implications
    Cinthia Mariel Olexen, Diego Alfredo Rosso, Wanda Nowak, Daniela Fortunati, Andrea Emilse Errasti and Eugenio Antonio Carrera Silva
    J Immunol June 29, 2022, ji2200147; DOI: https://doi.org/10.4049/jimmunol.2200147
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    Acetylcholine, Fatty Acids, and Lipid Mediators Are Linked to COVID-19 Severity
    Malena M. Pérez, Vinícius E. Pimentel, Carlos A. Fuzo, Pedro V. da Silva-Neto, Diana M. Toro, Thais F. C. Fraga-Silva, Luiz G. Gardinassi, Camilla N. S. Oliveira, Camila O. S. Souza, Nicola T. Torre-Neto, Jonatan C. S. de Carvalho, Thais C. De Leo, Viviani Nardini, Marley R. Feitosa, Rogerio S. Parra, José J. R. da Rocha, Omar Feres, Fernando C. Vilar, Gilberto G. Gaspar, Leticia F. Constant, Fátima M. Ostini, Augusto M. Degiovani, Alessandro P. Amorim, Angelina L. Viana, Ana P. M. Fernandes, Sandra R. Maruyama, Elisa M. S. Russo, Isabel K. F. M. Santos, Vânia L. D. Bonato, Cristina R. B. Cardoso, Carlos A. Sorgi, Marcelo Dias-Baruffi and Lúcia H. Faccioli on behalf of the ImmunoCOVID Brazilian Research Consortium
    J Immunol June 29, 2022, ji2200079; DOI: https://doi.org/10.4049/jimmunol.2200079

IMMUNE REGULATION

  • Open Access
    Plasmalogen-Mediated Activation of GPCR21 Regulates Cytolytic Activity of NK Cells against the Target Cells

    Author Choice Article

    Md Shamim Hossain, Shiro Mawatari and Takehiko Fujino
    J Immunol July 1, 2022, ji2200183; DOI: https://doi.org/10.4049/jimmunol.2200183
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    ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation
    Jinsam Chang, Antoine Bouchard, Yasser Bouklouch, Vincent Panneton, Joanna Li, Nikoletta Diamantopoulos, Saba Mohammaei, Roman Istomine, Fernando Alvarez, Ciriaco A. Piccirillo and Woong-Kyung Suh
    J Immunol June 27, 2022, ji2100897; DOI: https://doi.org/10.4049/jimmunol.2100897
  • Open Access
    CD11bhigh B Cells Increase after Stroke and Regulate Microglia

    Author Choice Article

    Janelle M. Korf, Pedram Honarpisheh, Eric C. Mohan, Anik Banerjee, Maria P. Blasco-Conesa, Parisa Honarpisheh, Gary U. Guzman, Romeesa Khan, Bhanu P. Ganesh, Amy L. Hazen, Juneyoung Lee, Aditya Kumar, Louise D. McCullough and Anjali Chauhan
    J Immunol June 22, 2022, ji2100884; DOI: https://doi.org/10.4049/jimmunol.2100884
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    Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic β Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice
    Joseph R. Podojil, Samantha Genardi, Ming-Yi Chiang, Sandeep Kakade, Tobias Neef, Tushar Murthy, Michael T. Boyne II, Adam Elhofy and Stephen D. Miller
    J Immunol June 20, 2022, ji2200208; DOI: https://doi.org/10.4049/jimmunol.2200208

INFECTIOUS DISEASE AND HOST RESPONSE

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    The Capsid Protein of Nervous Necrosis Virus Antagonizes Host Type I IFN Production by a Dual Strategy to Negatively Regulate Retinoic Acid–Inducible Gene-I–like Receptor Pathways
    Peng Jia, Wanwan Zhang, Yangxi Xiang, Xiaobing Lu, Xiaoqi Chen, Hongbo Pan, Meisheng Yi and Kuntong Jia
    J Immunol July 1, 2022, ji2100690; DOI: https://doi.org/10.4049/jimmunol.2100690
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    MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus
    Xi Wang, Cristina Cunha, Madeleine S. Grau, Shelly J. Robertson, João F. Lacerda, António Campos Jr., Katrien Lagrou, Johan Maertens, Sonja M. Best, Agostinho Carvalho and Joshua J. Obar
    J Immunol June 24, 2022, ji2100759; DOI: https://doi.org/10.4049/jimmunol.2100759
  • Open Access
    Epigenetic Reprogramming Leads to Downregulation of CD4 and Functional Changes in African Green Monkey Memory CD4+ T Cells

    Author Choice Article

    Andrew R. Rahmberg, Tovah E. Markowitz, Joseph C. Mudd, Vanessa Hirsch and Jason M. Brenchley
    J Immunol June 24, 2022, ji2200109; DOI: https://doi.org/10.4049/jimmunol.2200109

INNATE IMMUNITY AND INFLAMMATION

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    The Porcine and Chicken Innate DNA Sensing cGAS-STING-IRF Signaling Axes Exhibit Differential Species Specificity
    Sen Jiang, Jia Luo, Youwen Zhang, Qi Cao, Yuening Wang, Nengwen Xia, Wanglong Zheng, Nanhua Chen, François Meurens, Huiguang Wu and Jianzhong Zhu
    J Immunol July 1, 2022, ji2101212; DOI: https://doi.org/10.4049/jimmunol.2101212
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    Adenosine Alleviates Necrotizing Enterocolitis by Enhancing the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Newborns
    Dongmei Zhou, Meng Yao, Lijuan Zhang, Yingying Chen, Juan He, Yuxin Zhang, Haixu Xu, Pan Zhou, Wei Zhong, Zhi Yao and Jie Zhou
    J Immunol July 1, 2022, ji2200142; DOI: https://doi.org/10.4049/jimmunol.2200142
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    Glycolipid Metabolite β-Glucosylceramide Is a Neutrophil Extracellular Trap–Inducing Ligand of Mincle Released during Bacterial Infection and Inflammation
    Atul Sharma, Arun Chauhan, Pooja Chauhan, Dustin L. Evans, Randolph E. Szlabick, Mary O. Aaland, Bibhuti B. Mishra and Jyotika Sharma
    J Immunol June 29, 2022, ji2100855; DOI: https://doi.org/10.4049/jimmunol.2100855
  • Open Access
    KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity

    Author Choice Article

    Matthew D. Blunt, Andres Vallejo Pulido, Jack G. Fisher, Lara V. Graham, Amber D. P. Doyle, Rebecca Fulton, Matthew J. Carter, Marta Polak, Peter W. M. Johnson, Mark S. Cragg, Francesco Forconi and Salim I. Khakoo
    J Immunol June 29, 2022, ji2101139; DOI: https://doi.org/10.4049/jimmunol.2101139
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    Genetic Deletion of LRP5 and LRP6 in Macrophages Exacerbates Colitis-Associated Systemic Inflammation and Kidney Injury in Response to Intestinal Commensal Microbiota
    Indumathi Manoharan, Daniel Swafford, Arulkumaran Shanmugam, Nikhil Patel, Puttur D. Prasad, Riyaz Mohamed, Qingqing Wei, Zheng Dong, Muthusamy Thangaraju and Santhakumar Manicassamy
    J Immunol June 27, 2022, ji2101172; DOI: https://doi.org/10.4049/jimmunol.2101172
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Print ISSN 0022-1767        Online ISSN 1550-6606