Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis

Pengcheng Chen; Shang Wang; Kyathanahalli S. Janardhan; Rachel L. Zemans; Wenhai Deng; Peer Karmaus; Shudan Shen; Mary Sunday; Loretta G. Que; Michael B. Fessler; Xiao-Ping Zhong

doi:10.4049/jimmunol.1900566

Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis

Pengcheng Chen, Shang Wang, Kyathanahalli S. Janardhan, Rachel L. Zemans, Wenhai Deng, Peer Karmaus, Shudan Shen, Mary Sunday, Loretta G. Que, Michael B. Fessler and Xiao-Ping Zhong

J Immunol July 17, 2019, ji1900566; DOI: https://doi.org/10.4049/jimmunol.1900566

Pengcheng Chen

*Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710;

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Shang Wang

*Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710;

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Kyathanahalli S. Janardhan

†Integrated Laboratory Systems, Inc., and National Institutes of Health, Research Triangle Park, Durham, NC 27709;

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ORCID record for Kyathanahalli S. Janardhan

Rachel L. Zemans

‡Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

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Wenhai Deng

*Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710;

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Peer Karmaus

§Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, NC 27709;

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Shudan Shen

*Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710;

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Mary Sunday

¶Department of Pathology, Duke University Medical Center, Durham, NC 27710;

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Loretta G. Que

‖Department of Medicine, Duke University Medical Center, Durham, NC 27710;

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Michael B. Fessler

§Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, NC 27709;

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Xiao-Ping Zhong

*Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, NC 27710;

#Department of Immunology, Duke University Medical Center, Durham, NC 27710; and

**Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710

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The Journal of Immunology

Vol. 208, Issue 10

15 May 2022

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Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis

Pengcheng Chen, Shang Wang, Kyathanahalli S. Janardhan, Rachel L. Zemans, Wenhai Deng, Peer Karmaus, Shudan Shen, Mary Sunday, Loretta G. Que, Michael B. Fessler, Xiao-Ping Zhong

The Journal of Immunology July 17, 2019, ji1900566; DOI: 10.4049/jimmunol.1900566

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Efficient CD4Cre-Mediated Conditional KRas Expression in Alveolar Macrophages and Alveolar Epithelial Cells Causes Fatal Hyperproliferative Pneumonitis

Pengcheng Chen, Shang Wang, Kyathanahalli S. Janardhan, Rachel L. Zemans, Wenhai Deng, Peer Karmaus, Shudan Shen, Mary Sunday, Loretta G. Que, Michael B. Fessler, Xiao-Ping Zhong

The Journal of Immunology July 17, 2019, ji1900566; DOI: 10.4049/jimmunol.1900566

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