Polyfunctional CD4+ and CD8+ T Cell Responses to Tuberculosis Antigens in HIV-1–Infected Patients before and after Anti-Retroviral Treatment

Address correspondence and reprint requests to Dr. Jayne Sutherland, MRC Laboratories, P.O. Box 273, Banjul, The Gambia, West Africa. E-mail address: jsutherland{at}mrc.gm

↵1 Current address: University of Manchester, Manchester, United Kingdom.
↵2 Current address: Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
↵3 Current address: Bill and Melinda Gates Foundation, Seattle, WA 98102.

Article usage

Article usage: April 2010 to July 2022

	Abstract	Full	Pdf
Apr 2010	4	0	1
May 2010	213	40	184
Jun 2010	82	57	70
Jul 2010	40	38	35
Aug 2010	188	34	32
Sep 2010	47	25	23
Oct 2010	41	20	24
Nov 2010	43	21	26
Dec 2010	63	33	23
Total 2010	721	268	418
Jan 2011	39	16	12
Feb 2011	38	22	18
Mar 2011	64	13	24
Apr 2011	44	16	14
May 2011	38	16	13
Jun 2011	30	41	39
Jul 2011	26	23	19
Aug 2011	76	21	38
Sep 2011	37	26	44
Oct 2011	31	28	26
Nov 2011	42	32	21
Dec 2011	46	27	37
Total 2011	511	281	305
Jan 2012	37	25	32
Feb 2012	39	19	29
Mar 2012	39	30	743
Apr 2012	45	29	42
May 2012	52	18	31
Jun 2012	32	18	21
Jul 2012	34	26	23
Aug 2012	28	18	15
Sep 2012	51	12	20
Oct 2012	30	30	42
Nov 2012	46	22	32
Dec 2012	22	15	20
Total 2012	455	262	1050
Jan 2013	27	21	27
Feb 2013	29	11	22
Mar 2013	20	12	14
Apr 2013	32	11	17
May 2013	22	19	21
Jun 2013	30	16	19
Jul 2013	37	19	27
Aug 2013	12	14	15
Sep 2013	24	12	23
Oct 2013	17	10	20
Nov 2013	28	10	27
Dec 2013	21	11	3
Total 2013	299	166	235
Jan 2014	11	13	14
Feb 2014	16	19	15
Mar 2014	24	10	23
Apr 2014	10	14	28
May 2014	14	15	15
Jun 2014	27	9	21
Jul 2014	43	28	22
Aug 2014	14	28	14
Sep 2014	17	30	40
Oct 2014	19	15	42
Nov 2014	18	41	32
Dec 2014	26	12	26
Total 2014	239	234	292
Jan 2015	32	11	30
Feb 2015	16	8	38
Mar 2015	38	9	53
Apr 2015	12	12	27
May 2015	11	10	46
Jun 2015	11	9	27
Jul 2015	15	10	40
Aug 2015	20	9	33
Sep 2015	35	6	31
Oct 2015	30	14	37
Nov 2015	18	8	44
Dec 2015	61	12	38
Total 2015	299	118	444
Jan 2016	19	17	39
Feb 2016	7	12	60
Mar 2016	22	25	58
Apr 2016	10	8	35
May 2016	11	4	31
Jun 2016	10	11	37
Jul 2016	24	17	35
Aug 2016	5	9	14
Sep 2016	15	8	19
Oct 2016	11	9	17
Nov 2016	11	10	32
Dec 2016	11	12	40
Total 2016	156	142	417
Jan 2017	1	18	22
Feb 2017	2	22	13
Mar 2017	3	31	4
Apr 2017	3	25	14
May 2017	4	24	9
Jun 2017	4	15	4
Jul 2017	4	8	8
Aug 2017	3	7	14
Sep 2017	0	18	10
Oct 2017	3	18	12
Nov 2017	4	25	14
Dec 2017	2	13	5
Total 2017	33	224	129
Jan 2018	6	22	7
Feb 2018	9	26	13
Mar 2018	3	36	7
Apr 2018	0	14	7
May 2018	7	25	14
Jun 2018	5	20	12
Jul 2018	2	11	9
Aug 2018	3	24	13
Sep 2018	1	17	20
Oct 2018	12	22	11
Nov 2018	3	16	12
Dec 2018	3	32	14
Total 2018	54	265	139
Jan 2019	5	19	4
Feb 2019	2	13	6
Mar 2019	3	22	13
Apr 2019	5	16	10
May 2019	2	15	17
Jun 2019	5	14	10
Jul 2019	7	17	15
Aug 2019	1	12	4
Sep 2019	4	23	19
Oct 2019	4	48	8
Nov 2019	5	20	14
Dec 2019	5	17	10
Total 2019	48	236	130
Jan 2020	3	19	7
Feb 2020	3	19	7
Mar 2020	10	29	11
Apr 2020	10	15	2
May 2020	2	10	7
Jun 2020	2	15	7
Jul 2020	2	12	10
Aug 2020	3	20	2
Sep 2020	4	13	2
Oct 2020	4	11	7
Nov 2020	5	6	13
Dec 2020	6	17	13
Total 2020	54	186	88
Jan 2021	11	16	9
Feb 2021	3	8	10
Mar 2021	10	17	14
Apr 2021	9	17	18
May 2021	13	12	10
Jun 2021	2	17	9
Jul 2021	5	19	21
Aug 2021	4	17	1
Sep 2021	4	10	13
Oct 2021	1	10	19
Nov 2021	0	5	16
Dec 2021	5	13	8
Total 2021	67	161	148
Jan 2022	4	24	13
Feb 2022	8	8	8
Mar 2022	2	16	15
Apr 2022	8	8	8
May 2022	1	7	6
Jun 2022	3	13	9
Jul 2022	2	11	11
Total 2022	28	87	70
Total	2964	2630	3865