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IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3–Specific B Cell Receptor Knock-in Mouse
Hisashi Nomura, Naoko Wada, Hayato Takahashi, Yuko Kase, Jun Yamagami, Shohei Egami, Hisato Iriki, Miho Mukai, Aki Kamata, Hiromi Ito, Hideki Fujii, Tomoyuki Ishikura, Haruhiko Koseki, Takashi Watanabe, Taketo Yamada, Osamu Ohara, Shigeo Koyasu and Masayuki Amagai

J Immunol 208 (3) 582-593; February 1, 2022, doi: https://doi.org/10.4049/jimmunol.2100781
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Fewer LAG-3⁺ T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes
Britta E. Jones, Megan D. Maerz, Henry T. Bahnson, Ashwin Somasundaram, Lucas H. McCarthy, Cate Speake and Jane H. Buckner

J Immunol 208 (3) 594-602; February 1, 2022, doi: https://doi.org/10.4049/jimmunol.2100850
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The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism
Lauren M. F. Merlo, Weidan Peng, James B. DuHadaway, James D. Montgomery, George C. Prendergast, Alexander J. Muller and Laura Mandik-Nayak

J Immunol 208 (3) 571-581; February 1, 2022, doi: https://doi.org/10.4049/jimmunol.2100705
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Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell–like Differentiation in Patients with Granulomatosis with Polyangiitis
Sangmi Kim, Lena Boehme, Louise Nel, Alina Casian, Shirish Sangle, Estefania Nova-Lamperti, Vlad Seitan, Jo Spencer, Paul Lavender, David P. D'Cruz and Susan John

J Immunol ji2001331; published ahead of print January 17, 2022, doi: https://doi.org/10.4049/jimmunol.2001331
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Aire Controls Heterogeneity of Medullary Thymic Epithelial Cells for the Expression of Self-Antigens
Hitoshi Nishijima, Minoru Matsumoto, Junko Morimoto, Kazuyoshi Hosomichi, Nobuko Akiyama, Taishin Akiyama, Takeshi Oya, Koichi Tsuneyama, Hideyuki Yoshida and Mitsuru Matsumoto

J Immunol 208 (2) 303-320; January 15, 2022, doi: https://doi.org/10.4049/jimmunol.2100692
Open Access
CD8⁺ T Cells Expressing an HLA-DR1 Chimeric Antigen Receptor Target Autoimmune CD4⁺ T Cells in an Antigen-Specific Manner and Inhibit the Development of Autoimmune Arthritis
Karen B. Whittington, Amanda Prislovsky, Jacob Beaty, Lorraine Albritton, Marko Radic and Edward F. Rosloniec

J Immunol 208 (1) 16-26; January 1, 2022, doi: https://doi.org/10.4049/jimmunol.2100643
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Mouse Homologue of Human HLA-DO Does Not Preempt Autoimmunity but Controls Murine Gammaherpesvirus MHV68
Jean Lee, Emily Cullum, Kyle Stoltz, Niklas Bachmann, Zoe Strong, Danielle D. Millick, Lisa K. Denzin, Anthony Chang, Vera Tarakanova, Alexander V. Chervonsky and Tatyana Golovkina

J Immunol 207 (12) 2944-2951; December 15, 2021, doi: https://doi.org/10.4049/jimmunol.2100650
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Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis
Patrick O’Connell, Maja K. Blake, Sarah Godbehere, Yasser A. Aldhamen and Andrea Amalfitano

J Immunol 207 (12) 2952-2965; December 15, 2021, doi: https://doi.org/10.4049/jimmunol.2100813
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Btk Supports Autoreactive B Cell Development and Protects against Apoptosis but Is Expendable for Antigen Presentation
Lindsay E. Nyhoff, Amber S. Griffith, Emily S. Clark, James W. Thomas, Wasif N. Khan and Peggy L. Kendall

J Immunol 207 (12) 2922-2932; December 15, 2021, doi: https://doi.org/10.4049/jimmunol.2000558
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The Calcium Channel Inhibitor Nimodipine Shapes the Uveitogenic T Cells and Protects Mice from Experimental Autoimmune Uveitis through the p38–MAPK Signaling Pathway
Yunwei Hu, Guanyu Chen, Jun Huang, Zhuang Li, Zuoyi Li, Yanyan Xie, Yuxi Chen, He Li, Wenru Su, Xiaoqing Chen and Dan Liang

J Immunol 207 (12) 2933-2943; December 15, 2021, doi: https://doi.org/10.4049/jimmunol.2100568

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