Summary
Lymph node, spleen and peritoneal exudate cells from immunized guinea pigs produce antibody when deposited in the skin of isologous recipients. Presence of antibody is revealed by injecting recipients intravenously with dye and specific antigen 2 to 7 days after cell deposition. No synthesis was detected in nonisogeneic guinea pigs sensitized against donor-type lymphoid cells or in certain other homologous, nonsensitized recipients.
Footnotes
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↵1 This investigation was supported by United States Public Health Service Grant AI-04131 from the National Institute of Allergy and Infectious Diseases.
- Received August 2, 1966.
- Copyright © 1966 by The American Association of Immunologists, Inc.
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