Summary
Relatively tissue-free suspensions of Treponema pallidum, Nichols strain, were prepared by extracting the organism in rabbit serum-saline medium in equal parts. They were exposed to ultrasonic disintegration and the presence of antigens within the lysate and residue determined. Heat-labile and heat-stable (non-cardiolipin) antigens specific for T. pallidum, as well as antigens related to the lipopolysaccharide and protein (RP) components of the nonpathogenic Treponema reiteri, could be demonstrated. Further, the above antigens were shown to be unrelated to TPI antigen(s). The specific T. pallidum antigens within the lysate were found to be distinct from those within the residue.
Footnotes
-
↵1 These studies were carried out while the senior author was on sabbatical leave from the Department of Medical Microbiology and Immunology, University of California School of Medicine, Los Angeles, California. They were supported in part by a United Health Foundation Fellowship Grant from the New York Academy of Medicine, and in part by United States Public Health Service Research Grant CC-00115 from the Communicable Disease Center, Atlanta, Georgia.
- Received August 31, 1965.
- Copyright © 1966 by The American Association of Immunologists, Inc.
Pay Per Article - You may access this article (from the computer you are currently using) for 1 day for US$37.50
Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.
Log in using your username and password
In this issue
