Summary
Fab and F(ab′)2 from anti-WEE γ-globulin neutralized WEE virus in vitro but not in vivo. The results could not be explained by differences in heterogeneity of viral preparations or in the species of cell line used in the two assay systems.
Footnotes
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↵1 This study was supported by Grants C-05924-04 and CA-07732-01 from the National Cancer Institute, National Institutes of Health, United States Public Health Service, United States Department of Health, Education, and Welfare.
- Received August 20, 1965.
- Copyright © 1966 by The American Association of Immunologists, Inc.
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Difference in Mechanism of Viral Neutralization under in Vitro and in Vivo Conditions
