Summary
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1. Cross-neutralization tests were done with chicken and rabbit antisera, prepared against 3 strains of Newcastle virus and against a strain of mumps and of swine influenza virus. All 3 strains of Newcastle virus produced antisera effective against each other.
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2. Both chicken and rabbit antisera against mumps failed to neutralize Newcastle virus.
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3. Chicken antisera to Newcastle virus failed to neutralize mumps virus; but rabbit antisera prepared to the 3 strains of Newcastle gave inconsistent results against mumps and the possible relation of Newcastle and mumps viruses under this condition is being further tested.
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4. Several human sera with high titers of neutralization antibodies against Newcastle were successfully absorbed with mumps virus. The absorption was successful particularly when a dilution of the serum was used, and includes 1 serum which had a low titer of neutralization against mumps itself.
Footnotes
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↵1 This work was supported by a grant-in-aid from the National Microbiological Institute of the United States Public Health Service (C 1230).
- Received July 11, 1955.
- Copyright © 1956 by The American Association of Immunologists, Inc.
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