Skip to main content

Main menu

  • Home
  • Articles
    • Current Issue
    • Next in The JI
    • Archive
    • Brief Reviews
      • Neuroimmunology: To Sense and Protect
    • Pillars of Immunology
    • Translating Immunology
    • Most Read
    • Top Downloads
    • Annual Meeting Abstracts
  • COVID-19/SARS/MERS Articles
  • Info
    • About the Journal
    • For Authors
    • Journal Policies
    • Influence Statement
    • For Advertisers
  • Editors
  • Submit
    • Submit a Manuscript
    • Instructions for Authors
    • Journal Policies
  • Subscribe
    • Journal Subscriptions
    • Email Alerts
    • RSS Feeds
    • ImmunoCasts
  • More
    • Most Read
    • Most Cited
    • ImmunoCasts
    • AAI Disclaimer
    • Feedback
    • Help
    • Accessibility Statement
  • Other Publications
    • American Association of Immunologists
    • ImmunoHorizons

User menu

  • Subscribe
  • Log in

Search

  • Advanced search
The Journal of Immunology
  • Other Publications
    • American Association of Immunologists
    • ImmunoHorizons
  • Subscribe
  • Log in
The Journal of Immunology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Next in The JI
    • Archive
    • Brief Reviews
    • Pillars of Immunology
    • Translating Immunology
    • Most Read
    • Top Downloads
    • Annual Meeting Abstracts
  • COVID-19/SARS/MERS Articles
  • Info
    • About the Journal
    • For Authors
    • Journal Policies
    • Influence Statement
    • For Advertisers
  • Editors
  • Submit
    • Submit a Manuscript
    • Instructions for Authors
    • Journal Policies
  • Subscribe
    • Journal Subscriptions
    • Email Alerts
    • RSS Feeds
    • ImmunoCasts
  • More
    • Most Read
    • Most Cited
    • ImmunoCasts
    • AAI Disclaimer
    • Feedback
    • Help
    • Accessibility Statement
  • Follow The Journal of Immunology on Twitter
  • Follow The Journal of Immunology on RSS

Serological Studies on Infectious Mononucleosis and Viral Hepatitis with Human Erythrocytes Modified by Different Strains of Newcastle Disease Virus

Alfred S. Evans
J Immunol May 1, 1950, 64 (5) 411-420;
Alfred S. Evans
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Summary

  1. 1. Hemagglutinating properties of sera from cases of infectious mononucleosis and viral hepatitis, and certain other diseases have been studied, employing human red blood cells modified by adsorption and elution of Newcastle disease virus (NDV).

  2. 2. Serum from 17 per cent of 59 cases of infectious mononucleosis agglutinated red cells modified by the Connecticut strain of NDV in higher titer than found in serum of normal individuals, whereas serum from 74.5 per cent of the same cases agglutinated red cells similarly modified by an Australian strain. Individual titers were often in a much higher range with the latter strain.

  3. 3. Absorption experiments indicate that red cells modified by either strain of NDV react with the same component of serum.

  4. 4. Elevated titers were found in serums from 32 per cent of 40 cases of viral hepatitis studied with red cells modified by the Connecticut strain of NDV, and 26 per cent of 90 cases similarly studied using an Australian strain.

  5. 5. Elevated titers were obtained in 13 per cent of patients with other infectious diseases whose serum was tested against red cells altered by the Connecticut strain, and in 10 per cent employing an Australian strain.

  6. 6. The amount of residual virus present on the red cell after adsorption and elution, the hemagglutinin titer against chicken and human red cells, and the infectivity titer for eggs were all closely comparable for these virus strains as well as for 2 other strains of NDV.

  7. 7. When subjected to elevated temperatures, differences in the stability of the chicken red cell hemagglutinin of 4 strains of NDV were demonstrable.

Footnotes

  • ↵1 This investigation was aided by the Commission on Virus and Rickettsial Diseases, Armed Forces Epidemiological Board, Washington, D. C., and was supported (in part) by a grant from the Division of Research Grants and Fellowships of the National Institutes of Health, U. S. Public Health Service.

  • Received December 15, 1949.
  • Copyright © 1950 by The American Association of Immunologists, Inc.

Pay Per Article - You may access this article (from the computer you are currently using) for 1 day for US$37.50

Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.

Log in using your username and password

Forgot your user name or password?
PreviousNext
Back to top

In this issue

The Journal of Immunology
Vol. 64, Issue 5
1 May 1950
  • Table of Contents
  • Table of Contents (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about The Journal of Immunology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Serological Studies on Infectious Mononucleosis and Viral Hepatitis with Human Erythrocytes Modified by Different Strains of Newcastle Disease Virus
(Your Name) has forwarded a page to you from The Journal of Immunology
(Your Name) thought you would like to see this page from the The Journal of Immunology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Serological Studies on Infectious Mononucleosis and Viral Hepatitis with Human Erythrocytes Modified by Different Strains of Newcastle Disease Virus
Alfred S. Evans
The Journal of Immunology May 1, 1950, 64 (5) 411-420;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Serological Studies on Infectious Mononucleosis and Viral Hepatitis with Human Erythrocytes Modified by Different Strains of Newcastle Disease Virus
Alfred S. Evans
The Journal of Immunology May 1, 1950, 64 (5) 411-420;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

Cited By...

Similar Articles

Navigate

  • Home
  • Current Issue
  • Next in The JI
  • Archive
  • Brief Reviews
  • Pillars of Immunology
  • Translating Immunology

For Authors

  • Submit a Manuscript
  • Instructions for Authors
  • About the Journal
  • Journal Policies
  • Editors

General Information

  • Advertisers
  • Subscribers
  • Rights and Permissions
  • Accessibility Statement
  • Public Access
  • Privacy Policy
  • Disclaimer

Journal Services

  • Email Alerts
  • RSS Feeds
  • ImmunoCasts
  • Twitter

Copyright © 2021 by The American Association of Immunologists, Inc.

Print ISSN 0022-1767        Online ISSN 1550-6606