Summary
-
1. The findings of Besredka concerning the anti-anaphylactic action of certain narcotics were confirmed.
-
a. In the control experiments only 4 out of 25 guinea pigs survived the shocking reinjection.
-
b. Urethane administered to sensitized guinea pigs prior to the shocking reinjection led to the survival of 15 out of 30 animals.
-
c. Although ether inhalation led to the survival of three out of nine animals it is felt that these experiments are not conclusive.
-
d. Morphine hydrochloride does not protect guinea pigs from fatal anaphylactic shock.
-
-
2. Besredka's interpretation of this phenomenon, which assumes that the action of the narcotics takes place in the central nervous system, is held to be incorrect. An explanation is advanced on the basis of their action on the bronchial musculature.
Footnotes
-
↵1 Aided by a grant from the Department of Medicine of Cornell University Medical College.
- Received October 19, 1936.
- Copyright © 1937 by The American Association of Immunologists, Inc.
Pay Per Article - You may access this article (from the computer you are currently using) for 1 day for US$37.50
Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.
Log in using your username and password
In this issue
