Summary
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1. Neurotropic yellow fever virus of the French strain and of mouse origin has been transferred through nine passages in the testicular tissues of albino mice.
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2. Virus isolated from the sixth and seventh passages respectively in the testes of mice has been demonstrated to give a specific immunological reaction as yellow fever virus in passive immunity tests.
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3. Testicular virus of mouse origin when injected subcutaneously into a Macacus rhesus monkey resulted in the immunization of the animal, with the development of only a retarded and mild febrile reaction.
Footnotes
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↵1 The studies and observations on which this paper is based were conducted with the support and under the auspices of the International Health Division of The Rockefeller Foundation.
- Received April 27, 1933.
- Copyright © 1933 by The American Association of Immunologists, Inc.
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