The Journal of Immunology: 209 (3)

August 1, 2022; Volume 209,Issue 3

PILLARS OF IMMUNOLOGY

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Nucleic Acid Sensing and Systemic Lupus Erythematosus: The Danger of Self
Yong-Rui Zou and Anne Davidson

J Immunol August 1, 2022, 209 (3) 431-433; DOI: https://doi.org/10.4049/jimmunol.2200129

CLINICAL AND HUMAN IMMUNOLOGY

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TOLLIP Optimizes Dendritic Cell Maturation to Lipopolysaccharide and Mycobacterium tuberculosis
Sambasivan Venkatasubramanian, Robyn Pryor, Courtney Plumlee, Sarah B. Cohen, Jason D. Simmons, Alexander J. Warr, Andrew D. Graustein, Aparajita Saha, Thomas R. Hawn, Kevin B. Urdahl and Javeed A. Shah

J Immunol August 1, 2022, 209 (3) 435-445; DOI: https://doi.org/10.4049/jimmunol.2200030
Open Access
Characterization of Mycobacterium tuberculosis–Specific Th22 Cells and the Effect of Tuberculosis Disease and HIV Coinfection
Author Choice Article

Mohau S. Makatsa, F. Millicent A. Omondi, Rubina Bunjun, Robert J. Wilkinson, Catherine Riou and Wendy A. Burgers

J Immunol August 1, 2022, 209 (3) 446-455; DOI: https://doi.org/10.4049/jimmunol.2200140

IMMUNE REGULATION

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Carma3 Protects from Liver Injury by Preserving Mitochondrial Integrity in Liver Sinusoidal Endothelial Cells
Liqing Cheng, Zhanqi Wei, Zaopeng Yang, Renlin Lu, Ming Yang, Muchun Yu, Naixue Yang, Shulin Li, Mingyi Gao, Xueqiang Zhao and Xin Lin

J Immunol August 1, 2022, 209 (3) 456-464; DOI: https://doi.org/10.4049/jimmunol.2101195
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Tolerogenic Immune-Modifying Nanoparticles Encapsulating Multiple Recombinant Pancreatic β Cell Proteins Prevent Onset and Progression of Type 1 Diabetes in Nonobese Diabetic Mice
Joseph R. Podojil, Samantha Genardi, Ming-Yi Chiang, Sandeep Kakade, Tobias Neef, Tushar Murthy, Michael T. Boyne II, Adam Elhofy and Stephen D. Miller

J Immunol August 1, 2022, 209 (3) 465-475; DOI: https://doi.org/10.4049/jimmunol.2200208
Open Access
Deacetylation of K481 and K484 on Penaeid Shrimp Hemocyanin Is Critical for Antibacterial Activity
Author Choice Article

Junjie Nie, Jude Juventus Aweya, Zhixue Yu, Hui Zhou, Fan Wang, Defu Yao, Zhihong Zheng, Shengkang Li, Hongyu Ma and Yueling Zhang

J Immunol August 1, 2022, 209 (3) 476-487; DOI: https://doi.org/10.4049/jimmunol.2200078
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The Brucella Effector BspI Suppresses Inflammation via Inhibition of IRE1 Kinase Activity during Brucella Infection
Chen Li, Jingyu Wang, Wanchun Sun, Xiaofeng Liu, Jun Wang and Qisheng Peng

J Immunol August 1, 2022, 209 (3) 488-497; DOI: https://doi.org/10.4049/jimmunol.2200001

IMMUNE SYSTEM DEVELOPMENT

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A Novel CD135⁺ Subset of Mouse Monocytes with a Distinct Differentiation Pathway and Antigen-Presenting Properties
Naoka Kamio, Asumi Yokota, Yuichi Tokuda, Chie Ogasawara, Masakazu Nakano, Miki Nagao, Kei Tashiro, Taira Maekawa, Nobuyuki Onai and Hideyo Hirai

J Immunol August 1, 2022, 209 (3) 498-509; DOI: https://doi.org/10.4049/jimmunol.2100024

IMMUNOTHERAPY AND VACCINES

Open Access
LIGHT (TNFSF14) Costimulation Enhances Myeloid Cell Activation and Antitumor Immunity in the Setting of PD-1/PD-L1 and TIGIT Checkpoint Blockade
Author Choice Article

Kyung Jin Yoo, Kellsey Johannes, Louis E. González, Arpita Patel, Casey W. Shuptrine, Zachary Opheim, Karen Lenz, Kristen Campbell, Thuy-Ai Nguyen, Jayalakshmi Miriyala, Connor Smith, Ashlyn McGuire, Yi-Hsuan Tsai, Fatima Rangwala, Suresh de Silva, Taylor H. Schreiber and George Fromm

J Immunol August 1, 2022, 209 (3) 510-525; DOI: https://doi.org/10.4049/jimmunol.2101175
Open Access
Th2-Biased Transcriptional Profile Predicts HIV Envelope-Specific Polyfunctional CD4⁺ T Cells That Correlated with Reduced Risk of Infection in RV144 Trial
Author Choice Article

Kristen W. Cohen, Yuan Tian, Casey Thayer, Aaron Seese, Robert Amezquita, M. Juliana McElrath, Stephen C. De Rosa and Raphael Gottardo

J Immunol August 1, 2022, 209 (3) 526-534; DOI: https://doi.org/10.4049/jimmunol.2101211

INFECTIOUS DISEASE AND HOST RESPONSE

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A Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913
Julia Kazmierski, Carina Elsner, Katinka Döhner, Shuting Xu, Aurélie Ducroux, Fabian Pott, Jenny Jansen, Christian W. Thorball, Ole Zeymer, Xiaoyi Zhou, Roman Fedorov, Jacques Fellay, Markus W. Löffler, Alexander N. R. Weber, Beate Sodeik and Christine Goffinet

J Immunol August 1, 2022, 209 (3) 535-547; DOI: https://doi.org/10.4049/jimmunol.2100685
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Differential Roles for IL-1α and IL-1β in Pseudomonas aeruginosa Corneal Infection
Bridget Ratitong, Michaela E. Marshall, Morgan A. Dragan, Charissa M. Anunciado, Serena Abbondante and Eric Pearlman

J Immunol August 1, 2022, 209 (3) 548-558; DOI: https://doi.org/10.4049/jimmunol.2200110

INNATE IMMUNITY AND INFLAMMATION

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A Vitamin D–RelB/NF-κB Pathway Limits Chandipura Virus Multiplication by Rewiring the Homeostatic State of Autoregulatory Type 1 IFN–IRF7 Signaling
Yashika Ratra, Naveen Kumar, Manti K. Saha, Chandrima Bharadwaj, Chen Chongtham, Sachendra S. Bais, Guruprasad Medigeshi, Gopalakrishnan A. Arimbasseri and Soumen Basak

J Immunol August 1, 2022, 209 (3) 559-568; DOI: https://doi.org/10.4049/jimmunol.2101054
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ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic Female NOD Mice and Is Rapidly Upregulated by NF-κB in Pancreatic β-Cells
Thomas M. Martin, Susan J. Burke, Heidi M. Batdorf, David H. Burk, Sujoy Ghosh, Samuel D. Dupuy, Michael D. Karlstad and J. Jason Collier

J Immunol August 1, 2022, 209 (3) 569-581; DOI: https://doi.org/10.4049/jimmunol.2200065
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Heat Shock Protein 70 Is a Damage-Associated Molecular Pattern That by Binding to Lipopolysaccharide and β-1,3-Glucan–Binding Protein Activates the Prophenoloxidase System in Shrimp
Wisarut Junprung, Premruethai Supungul, Nutthapon Sangklai and Anchalee Tassanakajon

J Immunol August 1, 2022, 209 (3) 582-592; DOI: https://doi.org/10.4049/jimmunol.2100804

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Affinity-Driven Site-Specific High Mannose Modification Determines the Structural Polymerization and Function of Tetrameric IgM in a Primitive Vertebrate
Xiaoxue Yin, Xiaoyu Li, Liangliang Mu, Hao Bai, Yanjian Yang, Nuo Chen, Liting Wu, Shengli Fu, Jun Li, Wantao Ying and Jianmin Ye

J Immunol August 1, 2022, 209 (3) 593-605; DOI: https://doi.org/10.4049/jimmunol.2100921

TUMOR IMMUNOLOGY

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An In Vivo Model of Human Macrophages in Metastatic Melanoma
Valentin Voillet, Trisha R. Berger, Kelly M. McKenna, Kelly G. Paulson, Wei Hong Tan, Kimberly S. Smythe, Daniel S. Hunter, William J. Valente, Stephanie Weaver, Jean S. Campbell, Teresa S. Kim, David R. Byrd, Jason H. Bielas, Robert H. Pierce, Aude G. Chapuis, Raphaël Gottardo and Anthony Rongvaux

J Immunol August 1, 2022, 209 (3) 606-620; DOI: https://doi.org/10.4049/jimmunol.2101109
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PPP2R2D Suppresses Effector T Cell Exhaustion and Regulatory T Cell Expansion and Inhibits Tumor Growth in Melanoma
Wenliang Pan, Marc Scherlinger, Nobuya Yoshida, Maria G. Tsokos and George C. Tsokos

J Immunol August 1, 2022, 209 (3) 621-628; DOI: https://doi.org/10.4049/jimmunol.2200041
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Combination of NKG2A and PD-1 Blockade Improves Radiotherapy Response in Radioresistant Tumors
Nicholas G. Battaglia, Joseph D. Murphy, Taylor P. Uccello, Angela Hughson, Nicholas W. Gavras, Johnathan J. Caldon, Scott A. Gerber and Edith M. Lord

J Immunol August 1, 2022, 209 (3) 629-640; DOI: https://doi.org/10.4049/jimmunol.2100044

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PILLARS OF IMMUNOLOGY

CLINICAL AND HUMAN IMMUNOLOGY

IMMUNE REGULATION

IMMUNE SYSTEM DEVELOPMENT

IMMUNOTHERAPY AND VACCINES

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

TUMOR IMMUNOLOGY

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