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The Journal of Immunology

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Table of Contents

April 15, 2022; Volume 208,Issue 8

TOP READS

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    Top Reads

    UTX Restrains Plasma Cell Formation See article p. 1873

    lincRNA-Cox2 Regulates Lung Cytokine Genes See article p. 1886

    B Cell m6A Is Required for Optimal Germinal Centers See article p. 1924

    Skinks Make Do without γδ T Cells See article p. 1960

    Persistence of Virus-Specific Memory Tregs See article p. 1989

    J Immunol April 15, 2022, 208 (8) 1831-1832; DOI: https://doi.org/10.4049/jimmunol.2290004

LETTERS TO THE EDITOR

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    Comment on “Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer-BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines”
    Masaharu Somiya
    J Immunol April 15, 2022, 208 (8) 1833; DOI: https://doi.org/10.4049/jimmunol.2101082
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    Response to Comment on “Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer-BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines”
    Sandhya Bansal, Timothy Fleming and Thalachallour Mohanakumar
    J Immunol April 15, 2022, 208 (8) 1833-1834; DOI: https://doi.org/10.4049/jimmunol.2101067

BRIEF REVIEWS

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    Innate and Adaptive Immunity in Noninfectious Granulomatous Lung Disease
    Amy S. McKee, Shaikh M. Atif, Michael T. Falta and Andrew P. Fontenot
    J Immunol April 15, 2022, 208 (8) 1835-1843; DOI: https://doi.org/10.4049/jimmunol.2101159

CUTTING EDGE

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    Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice
    David J. Friedman, Monika Kizerwetter, Paul Belmonte, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Michael J. Shapiro, Haidong Dong and Virginia Smith Shapiro
    J Immunol April 15, 2022, 208 (8) 1845-1850; DOI: https://doi.org/10.4049/jimmunol.2101165
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    Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope
    Miranda H. Meeuwsen, Anne K. Wouters, Renate S. Hagedoorn, Michel G. D. Kester, Dennis F. G. Remst, Dirk M. van der Steen, Arnoud de Ru, Peter A. van Veelen, Jamie Rossjohn, Stephanie Gras, J. H. Frederik Falkenburg and Mirjam H. M. Heemskerk
    J Immunol April 15, 2022, 208 (8) 1851-1856; DOI: https://doi.org/10.4049/jimmunol.2101208

CLINICAL AND HUMAN IMMUNOLOGY

  • Distinct Cellular Immune Responses to SARS-CoV-2 in Pregnant Women
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    Distinct Cellular Immune Responses to SARS-CoV-2 in Pregnant Women
    Nardhy Gomez-Lopez, Roberto Romero, Li Tao, Meyer Gershater, Yaozhu Leng, Chengrui Zou, Marcelo Farias-Jofre, Jose Galaz, Derek Miller, Adi L. Tarca, Marcia Arenas-Hernandez, Gaurav Bhatti, Valeria Garcia-Flores, Zhenjie Liu, Robert Para, Tomi Kanninen, Ola Hadaya, Carmen Paredes and Yi Xu
    J Immunol April 15, 2022, 208 (8) 1857-1872; DOI: https://doi.org/10.4049/jimmunol.2101123

IMMUNE REGULATION

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    H3K27me3 Demethylase UTX Restrains Plasma Cell Formation
    Anna K. Kania, Madeline J. Price, Lou-Ella George-Alexander, Dillon G. Patterson, Sakeenah L. Hicks, Christopher D. Scharer and Jeremy M. Boss
    J Immunol April 15, 2022, 208 (8) 1873-1885; DOI: https://doi.org/10.4049/jimmunol.2100948
  • <em>lincRNA-Cox2</em> Functions to Regulate Inflammation in Alveolar Macrophages during Acute Lung Injury
    Open Access
    lincRNA-Cox2 Functions to Regulate Inflammation in Alveolar Macrophages during Acute Lung Injury

    Author Choice Article

    Elektra Kantzari Robinson, Atesh Worthington, Donna Poscablo, Barbara Shapleigh, Mays Mohammed Salih, Haley Halasz, Lucas Seninge, Benny Mosqueira, Valeriya Smaliy, E. Camilla Forsberg and Susan Carpenter
    J Immunol April 15, 2022, 208 (8) 1886-1900; DOI: https://doi.org/10.4049/jimmunol.2100743
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    IFITM3 Is Upregulated Characteristically in IL-15–Mediated Bystander-Activated CD8+ T Cells during Influenza Infection
    Seongju Jeong, Minwoo Jeon, Hoyoung Lee, So-Young Kim, Su-Hyung Park and Eui-Cheol Shin
    J Immunol April 15, 2022, 208 (8) 1901-1911; DOI: https://doi.org/10.4049/jimmunol.2100629
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    Prostaglandin E2–Induced AKT Activation Regulates the Life Span of Short-Lived Plasma Cells by Attenuating IRE1α Hyperactivation
    Wei Wang, Xiaodan Qin, Liang Lin, Jia Wu, Xiuyuan Sun, Ye Zhao, Yurong Ju, Ziheng Zhao, Liwei Ren, Xuewen Pang, Youfei Guan and Yu Zhang
    J Immunol April 15, 2022, 208 (8) 1912-1923; DOI: https://doi.org/10.4049/jimmunol.2100466
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    Mettl14-Mediated m6A Modification Is Essential for Germinal Center B Cell Response
    Hengjun Huang, Gaopu Zhang, Gui-Xin Ruan, Yuxing Li, Wenjing Chen, Jia Zou, Rui Zhang, Jing Wang, Sheng-Jian Ji, Shengli Xu and Xijun Ou
    J Immunol April 15, 2022, 208 (8) 1924-1936; DOI: https://doi.org/10.4049/jimmunol.2101071

IMMUNE SYSTEM DEVELOPMENT

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    Special AT-Rich Sequence-Binding Protein 1 Supports Survival and Maturation of Naive B Cells Stimulated by B Cell Receptors
    Takayuki Ozawa, Kentaro Fujii, Takao Sudo, Yukiko Doi, Ritsuko Nakai, Yasuhiro Shingai, Tomoaki Ueda, Yoshihiro Baba, Naoki Hosen and Takafumi Yokota
    J Immunol April 15, 2022, 208 (8) 1937-1946; DOI: https://doi.org/10.4049/jimmunol.2101097
  • The Lung Microenvironment Instructs Gene Transcription in Neonatal and Adult Alveolar Macrophages
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    The Lung Microenvironment Instructs Gene Transcription in Neonatal and Adult Alveolar Macrophages
    Asami Honda, Marten A. Hoeksema, Mashito Sakai, Sean J. Lund, Omar Lakhdari, Lindsay D. Butcher, Tara C. Rambaldo, Neal M. Sekiya, Chanond A. Nasamran, Kathleen M. Fisch, Eniko Sajti, Christopher K. Glass and Lawrence S. Prince
    J Immunol April 15, 2022, 208 (8) 1947-1959; DOI: https://doi.org/10.4049/jimmunol.2101192

IMMUNOGENETICS

  • Comparison of Reptilian Genomes Reveals Deletions Associated with the Natural Loss of γδ T Cells in Squamates
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    Comparison of Reptilian Genomes Reveals Deletions Associated with the Natural Loss of γδ T Cells in Squamates
    Kimberly A. Morrissey, Jordan M. Sampson, Megan Rivera, Lijing Bu, Victoria L. Hansen, Neil J. Gemmell, Michael G. Gardner, Terry Bertozzi and Robert D. Miller
    J Immunol April 15, 2022, 208 (8) 1960-1967; DOI: https://doi.org/10.4049/jimmunol.2101158

INFECTIOUS DISEASE AND HOST RESPONSE

  • Open Access
    Characterization of Altered Gene Expression and Histone Methylation in Peripheral Blood Mononuclear Cells Regulating Inflammation in COVID-19 Patients

    Author Choice Article

    Xiaoming Yang, Alex C. Rutkovsky, Juhua Zhou, Yin Zhong, Julian Reese, Timothy Schnell, Helmut Albrecht, William B. Owens, Prakash S. Nagarkatti and Mitzi Nagarkatti
    J Immunol April 15, 2022, 208 (8) 1968-1977; DOI: https://doi.org/10.4049/jimmunol.2101099
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    Interaction of lncRNA-CR33942 with Dif/Dorsal Facilitates Antimicrobial Peptide Transcriptions and Enhances Drosophila Toll Immune Responses
    Hongjian Zhou, Shengjie Li, Wanwan Pan, Shanshan Wu, Fei Ma and Ping Jin
    J Immunol April 15, 2022, 208 (8) 1978-1988; DOI: https://doi.org/10.4049/jimmunol.2100658
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    Virus-Specific Regulatory T Cells Persist as Memory in a Neurotropic Coronavirus Infection
    Alan Sariol, Jingxian Zhao, Juan E. Abrahante and Stanley Perlman
    J Immunol April 15, 2022, 208 (8) 1989-1997; DOI: https://doi.org/10.4049/jimmunol.2100794
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    Bona Fide Th17 Cells without Th1 Functional Plasticity Protect against Influenza
    Kunal Dhume, Caroline M. Finn, Priyadharshini Devarajan, Ayushi Singh, Joanne D. Tejero, Emily Prokop, Tara M. Strutt, Stewart Sell, Susan L. Swain and Karl Kai McKinstry
    J Immunol April 15, 2022, 208 (8) 1998-2007; DOI: https://doi.org/10.4049/jimmunol.2100801
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    IL-27 Enhances γδ T Cell–Mediated Innate Resistance to Primary Hookworm Infection in the Lungs
    Arjun Sharma, Jason B. Noon, Konstantinos Kontodimas, Lucien P. Garo, Johannes Platten, Lee J. Quinton, Joseph F. Urban Jr., Christoph Reinhardt and Markus Bosmann
    J Immunol April 15, 2022, 208 (8) 2008-2018; DOI: https://doi.org/10.4049/jimmunol.2000945

INNATE IMMUNITY AND INFLAMMATION

  • Lung Imaging Reveals Stroke-Induced Impairment in Pulmonary Intravascular Neutrophil Function, a Response Exacerbated with Aging
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    Lung Imaging Reveals Stroke-Induced Impairment in Pulmonary Intravascular Neutrophil Function, a Response Exacerbated with Aging
    Shu Wen Wen, Raymond Shim, Pam Hall, Justin Bedo, Jenny L. Wilson, Alyce J. Nicholls, Michael J. Hickey and Connie H. Y. Wong
    J Immunol April 15, 2022, 208 (8) 2019-2028; DOI: https://doi.org/10.4049/jimmunol.2100997
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    A Single Amino Acid Residue Defines the Difference in NLRP3 Inflammasome Activation between NEK7 and NEK6
    Devon Jeltema, Jihong Wang, Juan Cai, Nathan Kelley, Zhe Yang and Yuan He
    J Immunol April 15, 2022, 208 (8) 2029-2036; DOI: https://doi.org/10.4049/jimmunol.2101154

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    LECT2 Is a Novel Antibacterial Protein in Vertebrates
    Ya-Zhen Hu, Zi-You Ma, Chang-Song Wu, Jie Wang, Yong-An Zhang and Xu-Jie Zhang
    J Immunol April 15, 2022, 208 (8) 2037-2053; DOI: https://doi.org/10.4049/jimmunol.2100812

MUCOSAL IMMUNOLOGY

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    RORγt-Expressing Pathogenic CD4+ T Cells Cause Brain Inflammation during Chronic Colitis
    Michel Edwar Mickael, Suniti Bhaumik, Ayanabha Chakraborti, Alan A. Umfress, Thomas van Groen, Matthew Macaluso, John Totenhagen, Anna G. Sorace, James A. Bibb, David G. Standaert and Rajatava Basu
    J Immunol April 15, 2022, 208 (8) 2054-2066; DOI: https://doi.org/10.4049/jimmunol.2100869

TUMOR IMMUNOLOGY

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    E3 Ubiquitin Ligase Riplet Is Expressed in T Cells and Suppresses T Cell–Mediated Antitumor Immune Responses
    Asuka Iwamoto, Hirotake Tsukamoto, Hideki Nakayama and Hiroyuki Oshiumi
    J Immunol April 15, 2022, 208 (8) 2067-2076; DOI: https://doi.org/10.4049/jimmunol.2100096
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This Issue

The Journal of Immunology: 208 (8)
The Journal of Immunology
Vol. 208, Issue 8
15 Apr 2022
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Advertising (PDF)
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)

Issue highlights

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  • Innate and Adaptive Immunity in Noninfectious Granulomatous Lung Disease
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  • TOP READS
  • LETTERS TO THE EDITOR
  • BRIEF REVIEWS
  • CUTTING EDGE
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNE SYSTEM DEVELOPMENT
  • IMMUNOGENETICS
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • MUCOSAL IMMUNOLOGY
  • TUMOR IMMUNOLOGY
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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