On the cover: A composite image showing multiplexed immunohistochemical staining of seven complement proteins simultaneously from the knee joint synovial biopsy of an early rheumatoid arthritis patient. Color coding key is as follows: C3c, red; CFB, pink; CFH, cyan; CFHR4, magenta; MBL2, green; FCN3, white; C5b-9 (MAC), yellow. Banda, N. K., K. D. Deane, E. A. Bemis, C. Strickland, J. Seifert, K. Jordan, K. Goldman, Accelerating Medicines Partnership (AMP) RA/SLE Network, B. P. Morgan, L. W. Moreland, M. J. Lewis, C. Pitzalis, and V. M. Holers. 2022. Analysis of complement gene expression, clinical associations, and biodistribution of complement proteins in the synovium of early rheumatoid arthritis patients reveals unique pathophysiologic features. J. Immunol. 208: 2482–2496.