The Journal of Immunology: 208 (11)

June 1, 2022; Volume 208,Issue 11

PRESIDENT'S ADDRESS

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The All-Encompassing Importance of Innate Immunity
Jenny P.-Y. Ting

J Immunol June 1, 2022, 208 (11) 2445-2449; DOI: https://doi.org/10.4049/jimmunol.2290008
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The Regulation of Immunity
Jeremy M. Boss

J Immunol June 1, 2022, 208 (11) 2450-2455; DOI: https://doi.org/10.4049/jimmunol.2290007

PILLARS OF IMMUNOLOGY

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CCR5: The Receptor That Unlocks the Door for HIV Entry into Cells
Derya Unutmaz

J Immunol June 1, 2022, 208 (11) 2459-2460; DOI: https://doi.org/10.4049/jimmunol.2200108

CUTTING EDGE

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Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved
Mladen Jergović, Christopher P. Coplen, Jennifer L. Uhrlaub, Shawn C. Beitel, Jefferey L. Burgess, Karen Lutrick, Katherine D. Ellingson, Makiko Watanabe and Janko Nikolich-Žugich

J Immunol June 1, 2022, 208 (11) 2461-2465; DOI: https://doi.org/10.4049/jimmunol.2200175

AUTOIMMUNITY

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Restoration of Follicular T Regulatory/Helper Cell Balance by OX40L–JAG1 Cotreatment Suppresses Lupus Nephritis in NZBWF1/j Mice
Prabhakaran Kumar, Sivasangari Balakrishnan, Swarali Surendra Lele, Suman Setty, Shaurya Dhingra, Alan L. Epstein and Bellur S. Prabhakar

J Immunol June 1, 2022, 208 (11) 2467-2481; DOI: https://doi.org/10.4049/jimmunol.2200057

CLINICAL AND HUMAN IMMUNOLOGY

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Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features
Nirmal K. Banda, Kevin D. Deane, Elizabeth A. Bemis, Colin Strickland, Jennifer Seifert, Kimberly Jordan, Katriona Goldman, B. Paul Morgan, Larry W. Moreland, Myles J. Lewis, Costantino Pitzalis and V. Michael Holers

J Immunol June 1, 2022, 208 (11) 2482-2496; DOI: https://doi.org/10.4049/jimmunol.2101170

IMMUNE REGULATION

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Naturally Occurring Anti-Idiotypic Antibodies Portray a Largely Private Repertoire in Immune-Mediated Thrombotic Thrombocytopenic Purpura
Silvan R. Heeb, Monica Schaller and Johanna A. Kremer Hovinga

J Immunol June 1, 2022, 208 (11) 2497-2507; DOI: https://doi.org/10.4049/jimmunol.2100868

IMMUNOGENETICS

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Genome-Wide Mapping of Plasma IgG N-Glycan Quantitative Trait Loci Identifies a Potentially Causal Association between IgG N-Glycans and Rheumatoid Arthritis
Di Liu, Jing Dong, Jie Zhang, Xizhu Xu, Qiuyue Tian, Xiaoni Meng, Lijuan Wu, Deqiang Zheng, Xi Chu, Wei Wang, Qun Meng and Youxin Wang

J Immunol June 1, 2022, 208 (11) 2508-2514; DOI: https://doi.org/10.4049/jimmunol.2100080

INFECTIOUS DISEASE AND HOST RESPONSE

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Activation of CD4⁺ T Cell–Derived Cannabinoid Receptor 2 Signaling Exacerbates Sepsis via Inhibiting IL-10
Jincheng Chen, Fuxiang Wang, Su Zhang, Qiao Lin, Hui Xu, Tengfei Zhu, Ling Peng, Fulan Cen, Fang Li, Zhaoqin Wang, Carl G. Feng, Zhinan Yin, Yingxia Liu and Guoliang Zhang

J Immunol June 1, 2022, 208 (11) 2515-2522; DOI: https://doi.org/10.4049/jimmunol.2101015
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Dietary Cholesterol Causes Inflammatory Imbalance and Exacerbates Morbidity in Mice Infected with Influenza A Virus
Allison Y. Louie, Joseph Tingling, Evan Dray, Jamal Hussain, Daniel B. McKim, Kelly S. Swanson and Andrew J. Steelman

J Immunol June 1, 2022, 208 (11) 2523-2539; DOI: https://doi.org/10.4049/jimmunol.2100927
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Translationally Controlled Tumor Protein–Mediated Stabilization of Host Antiapoptotic Protein MCL-1 Is Critical for Establishment of Infection by Intramacrophage Parasite Leishmania donovani
Jayeeta Giri, Moumita Basu, Shalini Roy, Tarun Mishra, Kuladip Jana, Ajit Chande and Anindita Ukil

J Immunol June 1, 2022, 208 (11) 2540-2548; DOI: https://doi.org/10.4049/jimmunol.2100748
Open Access
Cyclooxygenase-Derived Prostaglandin E₂ Drives IL-1–Independent Mycobacterium bovis Bacille Calmette-Guérin–Triggered Skin Dendritic Cell Migration to Draining Lymph Node
Author Choice Article

Veronika Krmeská, Juliana Bernardi Aggio, Susanne Nylén, Pryscilla Fanini Wowk and Antonio Gigliotti Rothfuchs

J Immunol June 1, 2022, 208 (11) 2549-2557; DOI: https://doi.org/10.4049/jimmunol.2100981
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miR-146a Maintains Immune Tolerance of Kupffer Cells and Facilitates Hepatitis B Virus Persistence in Mice
Yongai Liu, Lijuan Qin, Jiuru Wang, Xialin Xie, Yu Zhang, Changfei Li, Zeliang Guan, Liyuan Qian, Lizhao Chen, Jun Hu and Songdong Meng

J Immunol June 1, 2022, 208 (11) 2558-2572; DOI: https://doi.org/10.4049/jimmunol.2100618
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Clonotypic IgH Response against Systemic Viral infection in Pronephros and Spleen of a Teleost Fish
Rosario Castro, Susana Magadán, Luc Jouneau, Vanessa Mhana, Hang-Phuong Pham, Encarnita Mariotti-Ferrandiz, Adrien Six, François Huetz and Pierre Boudinot

J Immunol June 1, 2022, 208 (11) 2573-2582; DOI: https://doi.org/10.4049/jimmunol.2200088

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Poor-Quality Vβ Recombination Signal Sequences and the DNA Damage Response ATM Kinase Collaborate to Establish TCRβ Gene Repertoire and Allelic Exclusion
Glendon S. Wu, Erica J. Culberson, Brittney M. Allyn and Craig H. Bassing

J Immunol June 1, 2022, 208 (11) 2583-2592; DOI: https://doi.org/10.4049/jimmunol.2100489

CORRECTIONS

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Correction: Myeloid-Specific Deficiency of Long-Chain Acyl CoA Synthetase 4 Reduces Inflammation by Remodeling Phospholipids and Reducing Production of Arachidonic Acid–Derived Proinflammatory Lipid Mediators
Andrew R. Reeves, Brian E. Sansbury, Meixia Pan, Xianlin Han, Matthew Spite and Andrew S. Greenberg

J Immunol June 1, 2022, 208 (11) 2593; DOI: https://doi.org/10.4049/jimmunol.2200133

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IMMUNE REGULATION

IMMUNOGENETICS

INFECTIOUS DISEASE AND HOST RESPONSE

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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