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The Journal of Immunology

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Table of Contents

January 1, 2022; Volume 208,Issue 1

TOP READS

  • You have accessRestricted access
    Top Reads

    HIV Exposure Alters T Cell Development in Infants See article p. 27

    ORAI1 Protects against SARS-CoV-2 See article p. 74

    Anti-Inflammatory Prions See article p. 85

    Engineered TGF-β–Resistant Therapeutic T Cells See article p. 169

    J Immunol January 1, 2022, 208 (1) 1-2; DOI: https://doi.org/10.4049/jimmunol.2190023

ANTIGEN RECOGNITION AND RESPONSES

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    Protective HLA Alleles Recruit Biased and Largely Similar Antigen-Specific T Cell Repertoires across Different Outcomes in HIV Infection
    Dan Koning, Esther D. Quakkelaar, Ingrid M. M. Schellens, Eric Spierings and Debbie van Baarle
    J Immunol January 1, 2022, 208 (1) 3-15; DOI: https://doi.org/10.4049/jimmunol.2001145

AUTOIMMUNITY

  • Open Access
    CD8+ T Cells Expressing an HLA-DR1 Chimeric Antigen Receptor Target Autoimmune CD4+ T Cells in an Antigen-Specific Manner and Inhibit the Development of Autoimmune Arthritis

    Author Choice Article

    Karen B. Whittington, Amanda Prislovsky, Jacob Beaty, Lorraine Albritton, Marko Radic and Edward F. Rosloniec
    J Immunol January 1, 2022, 208 (1) 16-26; DOI: https://doi.org/10.4049/jimmunol.2100643

CLINICAL AND HUMAN IMMUNOLOGY

  • Stereotypic Expansion of T Regulatory and Th17 Cells during Infancy Is Disrupted by HIV Exposure and Gut Epithelial Damage
    You have accessRestricted access
    Stereotypic Expansion of T Regulatory and Th17 Cells during Infancy Is Disrupted by HIV Exposure and Gut Epithelial Damage
    Sonwabile Dzanibe, Katie Lennard, Agano Kiravu, Melanie S. S. Seabrook, Berenice Alinde, Susan P. Holmes, Catherine A. Blish, Heather B. Jaspan and Clive M. Gray
    J Immunol January 1, 2022, 208 (1) 27-37; DOI: https://doi.org/10.4049/jimmunol.2100503
  • HuR-Targeted Inhibition Impairs Th2 Proinflammatory Responses in Asthmatic CD4<sup>+</sup> T Cells
    Open Access
    HuR-Targeted Inhibition Impairs Th2 Proinflammatory Responses in Asthmatic CD4+ T Cells

    Author Choice Article

    Fatemeh Fattahi, Jason S. Ellis, Michael Sylvester, Kristin Bahleda, Samuel Hietanen, Luis Correa, Njira L. Lugogo and Ulus Atasoy
    J Immunol January 1, 2022, 208 (1) 38-48; DOI: https://doi.org/10.4049/jimmunol.2100635

IMMUNE REGULATION

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    HLA-H*02:07 Is a Membrane-Bound Ligand of Denisovan Origin That Protects against Lysis by Activated Immune Effectors
    Lucas Hubert, Julien Paganini, Christophe Picard, Jacques Chiaroni, Laurent Abi-Rached, Pierre Pontarotti and Julie Di Cristofaro
    J Immunol January 1, 2022, 208 (1) 49-53; DOI: https://doi.org/10.4049/jimmunol.2100358

IMMUNOTHERAPY AND VACCINES

  • Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy
    Open Access
    Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy

    Author Choice Article

    Chris Y. Chiu, Judy J. Chang, Ashanti I. Dantanarayana, Ajantha Solomon, Vanessa A. Evans, Rachel Pascoe, Céline Gubser, Lydie Trautman, Rémi Fromentin, Nicolas Chomont, James H. McMahon, Paul U. Cameron, Thomas A. Rasmussen and Sharon R. Lewin
    J Immunol January 1, 2022, 208 (1) 54-62; DOI: https://doi.org/10.4049/jimmunol.2100367

INFECTIOUS DISEASE AND HOST RESPONSE

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    Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection
    Chandrashekhar D. Patil, Rahul Suryawanshi, Joshua Ames, Raghuram Koganti, Alex Agelidis, Divya Kapoor, Tejabhiram Yadavalli, Lulia Koujah, Henry C. Tseng and Deepak Shukla
    J Immunol January 1, 2022, 208 (1) 63-73; DOI: https://doi.org/10.4049/jimmunol.2100472
  • You have accessRestricted access
    ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling
    Beibei Wu, Arunachalam Ramaiah, Gustavo Garcia Jr., Spyridon Hasiakos, Vaithilingaraja Arumugaswami and Sonal Srikanth
    J Immunol January 1, 2022, 208 (1) 74-84; DOI: https://doi.org/10.4049/jimmunol.2100742

INNATE IMMUNITY AND INFLAMMATION

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    A Soluble PrPC Derivative and Membrane-Anchored PrPC in Extracellular Vesicles Attenuate Innate Immunity by Engaging the NMDA-R/LRP1 Receptor Complex
    Elisabetta Mantuano, Pardis Azmoon, Michael A. Banki, Christina J. Sigurdson, Wendy M. Campana and Steven L. Gonias
    J Immunol January 1, 2022, 208 (1) 85-96; DOI: https://doi.org/10.4049/jimmunol.2100412
  • You have accessRestricted access
    Divergent Genetic Regulation of Nitric Oxide Production between C57BL/6J and Wild-Derived PWD/PhJ Mice Controls Postactivation Mitochondrial Metabolism, Cell Survival, and Bacterial Resistance in Dendritic Cells
    Julia P. Snyder, Soyeon K. Gullickson, Roxana del Rio-Guerra, Andrea Sweezy, Bay Vagher, Tyler C. Hogan, Karolyn G. Lahue, Julie A. Reisz, Angelo D’Alessandro, Dimitry N. Krementsov and Eyal Amiel
    J Immunol January 1, 2022, 208 (1) 97-109; DOI: https://doi.org/10.4049/jimmunol.2100375
  • Nanoparticle-Induced Airway Eosinophilia Is Independent of ILC2 Signaling but Associated With Sex Differences in Macrophage Phenotype Development
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    Nanoparticle-Induced Airway Eosinophilia Is Independent of ILC2 Signaling but Associated With Sex Differences in Macrophage Phenotype Development
    Jessica L. Ray, Pam K. Shaw, Britten Postma, Celine A. Beamer and Andrij Holian
    J Immunol January 1, 2022, 208 (1) 110-120; DOI: https://doi.org/10.4049/jimmunol.2100769
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    Serglycin Is Involved in Adipose Tissue Inflammation in Obesity
    Atanaska I. Doncheva, Frode A. Norheim, Marit Hjorth, Mirjana Grujic, Aida Paivandy, Simon N. Dankel, Jens Kristoffer Hertel, Tone G. Valderhaug, Yvonne Böttcher, Johan Fernø, Gunnar Mellgren, Knut T. Dalen, Gunnar Pejler and Svein O. Kolset
    J Immunol January 1, 2022, 208 (1) 121-132; DOI: https://doi.org/10.4049/jimmunol.2100231
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    Unexpected Off-Target Activities for Recombinant C5a in Human Macrophages
    Xaria X. Li, Declan M. Gorman, John D. Lee, Richard J. Clark and Trent M. Woodruff
    J Immunol January 1, 2022, 208 (1) 133-142; DOI: https://doi.org/10.4049/jimmunol.2100444

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences
    Alina Tarsalainen, Yaakov Maman, Fei-Long Meng, Minna K. Kyläniemi, Anni Soikkeli, Paulina Budzyńska, Jessica J. McDonald, Filip Šenigl, Frederic W. Alt, David G. Schatz and Jukka Alinikula
    J Immunol January 1, 2022, 208 (1) 143-154; DOI: https://doi.org/10.4049/jimmunol.2100923
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    Prosurvival IL-7–Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1–TCF1–Id3 and Metabolic AMPKα1–ULK1–ATG7 Pathways
    Aizhang Xu, Scot C. Leary, Md. Fahmid Islam, Zhaojia Wu, Kalpana Kalyanasundaram Bhanumathy, Anjuman Ara, Rajni Chibbar, Andrew Fleywald, Khawaja Ashfaque Ahmed and Jim Xiang
    J Immunol January 1, 2022, 208 (1) 155-168; DOI: https://doi.org/10.4049/jimmunol.2100452

TUMOR IMMUNOLOGY

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    Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β
    Jonathan D. Silk, Rachel J. M. Abbott, Katherine J. Adams, Alan D. Bennett, Sara Brett, Terri V. Cornforth, Katherine L. Crossland, David J. Figueroa, Junping Jing, Caitriona O’Connor, Annette Pachnio, Lea Patasic, Carlos E. Peredo, Adriano Quattrini, Laura L. Quinn, Alistair G. Rust, Manoj Saini, Joseph P. Sanderson, Dylan Steiner, Barbara Tavano, Preetha Viswanathan, Guy E. Wiedermann, Ryan Wong, Bent K. Jakobsen, Cedrik M. Britten, Andrew B. Gerry and Joanna E. Brewer
    J Immunol January 1, 2022, 208 (1) 169-180; DOI: https://doi.org/10.4049/jimmunol.2001357

NOVEL IMMUNOLOGICAL METHODS

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    Cas9-Based Local Enrichment and Genomics Sequence Revision of Megabase-Sized Shark IgNAR Loci
    Hongming Dong, Yaolei Zhang, Jiahao Wang, Haitao Xiang, Tianhang Lv, Likun Wei, Shaosen Yang, Xiaopan Liu, Bingzhao Ren, Xiuqing Zhang, Lirong Liu, Jun Cao, Meiniang Wang, Jiahai Shi and Naibo Yang
    J Immunol January 1, 2022, 208 (1) 181-189; DOI: https://doi.org/10.4049/jimmunol.2100844
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This Issue

The Journal of Immunology: 208 (1)
The Journal of Immunology
Vol. 208, Issue 1
1 Jan 2022
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)

Issue highlights

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Jump to

  • TOP READS
  • ANTIGEN RECOGNITION AND RESPONSES
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • TUMOR IMMUNOLOGY
  • NOVEL IMMUNOLOGICAL METHODS
  • Highlights
  • Most Cited
  • Most Read
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606