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The Role of Properdin in C5 Convertase Activity and C5b-9 Formation in the Complement Alternative Pathway

Marloes A. H. M. Michels, Rianne J. F. Maas, Thea J. A. M. van der Velden, Nicole C. A. J. van de Kar, Lambertus P. W. J. van den Heuvel, Elena B. Volokhina and on behalf of the COMBAT Consortium
J Immunol November 15, 2021, 207 (10) 2465-2472; DOI: https://doi.org/10.4049/jimmunol.2100238
Marloes A. H. M. Michels
*Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen, the Netherlands;
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  • ORCID record for Marloes A. H. M. Michels
Rianne J. F. Maas
†Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands;
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Thea J. A. M. van der Velden
*Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen, the Netherlands;
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Nicole C. A. J. van de Kar
*Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen, the Netherlands;
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Lambertus P. W. J. van den Heuvel
*Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen, the Netherlands;
†Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands;
‡Department of Pediatrics/Pediatric Nephrology, University Hospitals Leuven, Leuven, Belgium; and
§Department of Development and Regeneration, University Hospitals Leuven, Leuven, Belgium
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Elena B. Volokhina
*Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen, the Netherlands;
†Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands;
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The Journal of Immunology: 207 (10)
The Journal of Immunology
Vol. 207, Issue 10
15 Nov 2021
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The Role of Properdin in C5 Convertase Activity and C5b-9 Formation in the Complement Alternative Pathway
Marloes A. H. M. Michels, Rianne J. F. Maas, Thea J. A. M. van der Velden, Nicole C. A. J. van de Kar, Lambertus P. W. J. van den Heuvel, Elena B. Volokhina, on behalf of the COMBAT Consortium
The Journal of Immunology November 15, 2021, 207 (10) 2465-2472; DOI: 10.4049/jimmunol.2100238

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The Role of Properdin in C5 Convertase Activity and C5b-9 Formation in the Complement Alternative Pathway
Marloes A. H. M. Michels, Rianne J. F. Maas, Thea J. A. M. van der Velden, Nicole C. A. J. van de Kar, Lambertus P. W. J. van den Heuvel, Elena B. Volokhina, on behalf of the COMBAT Consortium
The Journal of Immunology November 15, 2021, 207 (10) 2465-2472; DOI: 10.4049/jimmunol.2100238
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