The Journal of Immunology: 206 (1)

January 1, 2021; Volume 206,Issue 1

BRIEF REVIEWS

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Encephalitogenic and Regulatory CD8 T Cells in Multiple Sclerosis and Its Animal Models
Taryn E. Mockus, Ashley Munie, Jeffrey R. Atkinson and Benjamin M. Segal

J Immunol January 1, 2021, 206 (1) 3-10; DOI: https://doi.org/10.4049/jimmunol.2000797

ALLERGY AND OTHER HYPERSENSITIVITIES

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PRMT1 Modulates Processing of Asthma-Related Primary MicroRNAs (Pri-miRNAs) into Mature miRNAs in Lung Epithelial Cells
Weiqi Zhai, Haoming Sun, Zhi Li, Li Li, Ai Jin, Yuwen Li, Jian Chen, Xiaojun Yang, Qingzhu Sun, Shemin Lu and Michael Roth

J Immunol January 1, 2021, 206 (1) 11-22; DOI: https://doi.org/10.4049/jimmunol.2000887

CLINICAL AND HUMAN IMMUNOLOGY

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A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients
Monty B. Mazer, Charles C. Caldwell, Jodi Hanson, Daniel Mannion, Isaiah R. Turnbull, Anne Drewry, Dale Osborne, Andrew Walton, Tessa Blood, Lyle L. Moldawer, Scott Brakenridge, Kenneth E. Remy and Richard S. Hotchkiss

J Immunol January 1, 2021, 206 (1) 23-36; DOI: https://doi.org/10.4049/jimmunol.2001088
Open Access
Systematic Examination of Antigen-Specific Recall T Cell Responses to SARS-CoV-2 versus Influenza Virus Reveals a Distinct Inflammatory Profile
Author Choice Article

Jaclyn C. Law, Wan Hon Koh, Patrick Budylowski, Jonah Lin, FengYun Yue, Kento T. Abe, Bhavisha Rathod, Melanie Girard, Zhijie Li, James M. Rini, Samira Mubareka, Allison McGeer, Adrienne K. Chan, Anne-Claude Gingras, Tania H. Watts and Mario A. Ostrowski

J Immunol January 1, 2021, 206 (1) 37-50; DOI: https://doi.org/10.4049/jimmunol.2001067
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Redistribution of Monocyte Subsets in Obstructive Sleep Apnea Syndrome Patients Leads to an Imbalanced PD-1/PD-L1 Cross-Talk with CD4/CD8 T Cells
Christina Polasky, Armin Steffen, Kristin Loyal, Christian Lange, Karl-Ludwig Bruchhage and Ralph Pries

J Immunol January 1, 2021, 206 (1) 51-58; DOI: https://doi.org/10.4049/jimmunol.2001047

IMMUNE REGULATION

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Expression of GM-CSF Is Regulated by Fli-1 Transcription Factor, a Potential Drug Target
Xuan Wang, Mara Lennard Richard, Pengfei Li, Brittany Henry, Steven Schutt, Xue-Zhong Yu, Hongkuan Fan, Weiru Zhang, Gary Gilkeson and Xian K. Zhang

J Immunol January 1, 2021, 206 (1) 59-66; DOI: https://doi.org/10.4049/jimmunol.2000664
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In Activated Murine Mast Cells, NFATc2 Is Critical for the Production of Autocrine IL-3, Thereby Promoting the Expression of IL-9
Farhad Sabbaghi, Lorenz Ullner, Toszka Bohn, Jennifer Hahlbrock, Tobias Bopp, Edgar Schmitt, Matthias Klein and Michael Stassen

J Immunol January 1, 2021, 206 (1) 67-76; DOI: https://doi.org/10.4049/jimmunol.1900310
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E3 Ubiquitin Ligase RNF114 Inhibits Innate Immune Response to Red-Spotted Grouper Nervous Necrosis Virus Infection in Sea Perch by Targeting MAVS and TRAF3 to Mediate Their Degradation
Yangxi Xiang, Wanwan Zhang, Peng Jia, Xiaobing Lu, Wei Liu, Meisheng Yi and Kuntong Jia

J Immunol January 1, 2021, 206 (1) 77-88; DOI: https://doi.org/10.4049/jimmunol.2000083
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Foxo1 Serine 209 Is a Critical Regulatory Site of CD8 T Cell Differentiation and Survival
Leonard Benjamin Hills, Leena Abdullah, Hannah E. Lust, Hanna Degefu and Yina H. Huang

J Immunol January 1, 2021, 206 (1) 89-100; DOI: https://doi.org/10.4049/jimmunol.2000216

IMMUNOGENETICS

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Sex-Biased Aging Effects on Ig Somatic Hypermutation Targeting
Ang Cui, Daniel G. Chawla and Steven H. Kleinstein

J Immunol January 1, 2021, 206 (1) 101-108; DOI: https://doi.org/10.4049/jimmunol.2000576

INFECTIOUS DISEASE AND HOST RESPONSE

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SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals
Cecilie Bo Hansen, Ida Jarlhelt, Laura Pérez-Alós, Lone Hummelshøj Landsy, Mette Loftager, Anne Rosbjerg, Charlotte Helgstrand, Jais Rose Bjelke, Thomas Egebjerg, Joseph G. Jardine, Charlotte Sværke Jørgensen, Kasper Iversen, Rafael Bayarri-Olmos, Peter Garred and Mikkel-Ole Skjoedt

J Immunol January 1, 2021, 206 (1) 109-117; DOI: https://doi.org/10.4049/jimmunol.2000898
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IL-4 Treatment Mitigates Experimental Cerebral Malaria by Reducing Parasitemia, Dampening Inflammation, and Lessening the Cytotoxicity of T Cells
Xianzhu Wu, Ramesh P. Thylur, Kiran K. Dayanand, Kishore Punnath, Christopher C. Norbury and D. Channe Gowda

J Immunol January 1, 2021, 206 (1) 118-131; DOI: https://doi.org/10.4049/jimmunol.2000779
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The Invariant NKT Cell Response Has Differential Signaling Requirements during Antigen-Dependent and Antigen-Independent Activation
Courtney K. Anderson, Shanelle P. Reilly and Laurent Brossay

J Immunol January 1, 2021, 206 (1) 132-140; DOI: https://doi.org/10.4049/jimmunol.2000870

INNATE IMMUNITY AND INFLAMMATION

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Sex Differences in Macrophage Responses to Obesity-Mediated Changes Determine Migratory and Inflammatory Traits
Kuan-Hui Ethan Chen, Nancy M. Lainez and Djurdjica Coss

J Immunol January 1, 2021, 206 (1) 141-153; DOI: https://doi.org/10.4049/jimmunol.2000490
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NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense
Saeko Aoyama-Ishiwatari, Tomohiko Okazaki, Shun-ichiro Iemura, Tohru Natsume, Yasushi Okada and Yukiko Gotoh

J Immunol January 1, 2021, 206 (1) 154-163; DOI: https://doi.org/10.4049/jimmunol.2000306
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Deficiency of the Intramembrane Protease SPPL2a Alters Antimycobacterial Cytokine Responses of Dendritic Cells
Ann-Christine Gradtke, Torben Mentrup, Christian H. K. Lehmann, Florencia Cabrera-Cabrera, Christine Desel, Darian Okakpu, Maike Assmann, Alexander Dalpke, Ulrich E. Schaible, Diana Dudziak and Bernd Schröder

J Immunol January 1, 2021, 206 (1) 164-180; DOI: https://doi.org/10.4049/jimmunol.2000151
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A PKCβ–LYN–PYK2 Signaling Axis Is Critical for MCP-1–Dependent Migration and Adhesion of Monocytes
Pradip Das, Srabani Pal, Claudine M. Oldfield, Kowsalya Thillai, Sinjini Bala, Kevin A. Carnevale, Martha K. Cathcart and Ashish Bhattacharjee

J Immunol January 1, 2021, 206 (1) 181-192; DOI: https://doi.org/10.4049/jimmunol.1900706

TUMOR IMMUNOLOGY

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SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment
Patrick O’Connell, Sean Hyslop, Maja K. Blake, Sarah Godbehere, Andrea Amalfitano and Yasser A. Aldhamen

J Immunol January 1, 2021, 206 (1) 193-205; DOI: https://doi.org/10.4049/jimmunol.2000300

NOVEL IMMUNOLOGICAL METHODS

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Multibatch Cytometry Data Integration for Optimal Immunophenotyping
Masato Ogishi, Rui Yang, Conor Gruber, Peng Zhang, Simon J. Pelham, András N. Spaan, Jérémie Rosain, Marwa Chbihi, Ji Eun Han, V. Koneti Rao, Leena Kainulainen, Jacinta Bustamante, Bertrand Boisson, Dusan Bogunovic, Stéphanie Boisson-Dupuis and Jean-Laurent Casanova

J Immunol January 1, 2021, 206 (1) 206-213; DOI: https://doi.org/10.4049/jimmunol.2000854
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High-Sensitivity Assessment of Phagocytosis by Persistent Association-Based Normalization
Therese de Neergaard, Martin Sundwall, Sebastian Wrighton and Pontus Nordenfelt

J Immunol January 1, 2021, 206 (1) 214-224; DOI: https://doi.org/10.4049/jimmunol.2000032
Open Access
Affinity Maturation of B7-H6 Translates into Enhanced NK Cell–Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement
Author Choice Article

Lukas Pekar, Katja Klausz, Michael Busch, Bernhard Valldorf, Harald Kolmar, Daniela Wesch, Hans-Heinrich Oberg, Steffen Krohn, Ammelie Svea Boje, Carina Lynn Gehlert, Lars Toleikis, Simon Krah, Tushar Gupta, Brian Rabinovich, Stefan Zielonka and Matthias Peipp

J Immunol January 1, 2021, 206 (1) 225-236; DOI: https://doi.org/10.4049/jimmunol.2001004

CORRECTIONS

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Correction: Antibodies against Phosphorylcholine and Malondialdehyde during the First Two Years of Life
Divya Thiagarajan, Susanna L. Lundström, Göran Pershagen, Catarina Almqvist, Ellika Andolf, Anna Hedman, Oscar Berg, Nina Oparina and Johan Frostegård

J Immunol January 1, 2021, 206 (1) 237; DOI: https://doi.org/10.4049/jimmunol.2001224
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Correction: Zebrafish F-box Protein fbxo3 Negatively Regulates Antiviral Response through Promoting K27-Linked Polyubiquitination of the Transcription Factors irf3 and irf7
Zhi Li, Sijia Fan, Jing Wang, Xiaoyun Chen, Qian Liao, Xing Liu, Gang Ouyang, Hong Cao and Wuhan Xiao

J Immunol January 1, 2021, 206 (1) 238; DOI: https://doi.org/10.4049/jimmunol.2001164

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TOP READS

BRIEF REVIEWS

ALLERGY AND OTHER HYPERSENSITIVITIES

CLINICAL AND HUMAN IMMUNOLOGY

IMMUNE REGULATION

IMMUNOGENETICS

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

TUMOR IMMUNOLOGY

NOVEL IMMUNOLOGICAL METHODS

CORRECTIONS

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