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Zebrafish F-box Protein fbxo3 Negatively Regulates Antiviral Response through Promoting K27-Linked Polyubiquitination of the Transcription Factors irf3 and irf7

Zhi Li, Sijia Fan, Jing Wang, Xiaoyun Chen, Qian Liao, Xing Liu, Gang Ouyang, Hong Cao and Wuhan Xiao
J Immunol October 1, 2020, 205 (7) 1897-1908; DOI: https://doi.org/10.4049/jimmunol.2000305
Zhi Li
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
¶University of Chinese Academy of Sciences, Beijing 100049, China
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Sijia Fan
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
¶University of Chinese Academy of Sciences, Beijing 100049, China
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Jing Wang
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
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  • ORCID record for Jing Wang
Xiaoyun Chen
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
¶University of Chinese Academy of Sciences, Beijing 100049, China
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Qian Liao
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
¶University of Chinese Academy of Sciences, Beijing 100049, China
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Xing Liu
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
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Gang Ouyang
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
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Hong Cao
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
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Wuhan Xiao
*State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
†The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
§The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
¶University of Chinese Academy of Sciences, Beijing 100049, China
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Article Information

vol. 205 no. 7 1897-1908
DOI 
https://doi.org/10.4049/jimmunol.2000305
PubMed 
32859728

Published By 
The American Association of Immunologists, Inc.
Print ISSN 
0022-1767
Online ISSN 
1550-6606
History 
  • Received March 20, 2020
  • Accepted July 29, 2020
  • Published online September 21, 2020.

Article Versions

  • Older version (August 28, 2020 - 08:25).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2020 by The American Association of Immunologists, Inc.

Author Information

  1. Zhi Li*,†,‡,§,¶,
  2. Sijia Fan*,†,‡,§,¶,
  3. Jing Wang*,†,‡,§,
  4. Xiaoyun Chen*,†,‡,§,¶,
  5. Qian Liao*,†,‡,§,¶,
  6. Xing Liu*,†,‡,§,
  7. Gang Ouyang*,†,‡,§,
  8. Hong Cao*,†,‡,§ and
  9. Wuhan Xiao*,†,‡,§,¶
  1. *State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
  2. †The Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
  3. ‡The Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China;
  4. §The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan 430072, China; and
  5. ¶University of Chinese Academy of Sciences, Beijing 100049, China
  1. Address correspondence and reprint requests to Prof. Wuhan Xiao, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, People’s Republic of China. E-mail address: w-xiao{at}ihb.ac.cn
View Full Text

Funding

  • Strategic Priority Research Program of the Chinese Academy of Sciences

    XDA24010308
  • National Natural Science Foundation of China

    31830101; 31721005; 31671315
  • National Key Research and Development Program of China

    2018YFD0900602

Article usage

Article usage: August 2020 to January 2021

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Aug 2020235021
Sep 20206851622
Oct 2020132297
Nov 20201211410
Dec 20207378
Total 202012466668
Jan 2021651110
Total 2021651110
Total13117778

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The Journal of Immunology: 205 (7)
The Journal of Immunology
Vol. 205, Issue 7
1 Oct 2020
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Zebrafish F-box Protein fbxo3 Negatively Regulates Antiviral Response through Promoting K27-Linked Polyubiquitination of the Transcription Factors irf3 and irf7
Zhi Li, Sijia Fan, Jing Wang, Xiaoyun Chen, Qian Liao, Xing Liu, Gang Ouyang, Hong Cao, Wuhan Xiao
The Journal of Immunology October 1, 2020, 205 (7) 1897-1908; DOI: 10.4049/jimmunol.2000305

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Zebrafish F-box Protein fbxo3 Negatively Regulates Antiviral Response through Promoting K27-Linked Polyubiquitination of the Transcription Factors irf3 and irf7
Zhi Li, Sijia Fan, Jing Wang, Xiaoyun Chen, Qian Liao, Xing Liu, Gang Ouyang, Hong Cao, Wuhan Xiao
The Journal of Immunology October 1, 2020, 205 (7) 1897-1908; DOI: 10.4049/jimmunol.2000305
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