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The Journal of Immunology

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Table of Contents

December 15, 2020; Volume 205,Issue 12

TOP READS

  • You have accessRestricted access
    Top Reads

    Hindering Autoimmunity See article p. 3247

    Plasma Proteins Influence the T Cell Response to HIV See article p. 3348

    CD28 Agonism Curbs Sepsis See article p. 3358

    Kras Contributions to Graft-versus-Host Disease See article p. 3480

    J Immunol December 15, 2020, 205 (12) 3235-3236; DOI: https://doi.org/10.4049/jimmunol.2090020

BRIEF REVIEWS

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    A Case for Phosphoinositide 3-Kinase–Targeted Therapy for Infectious Disease
    Folayemi Adefemi, David A. Fruman and Aaron J. Marshall
    J Immunol December 15, 2020, 205 (12) 3237-3245; DOI: https://doi.org/10.4049/jimmunol.2000599

AUTOIMMUNITY

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    T Follicular Regulatory Cell–Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity
    Waradon Sungnak, Allon Wagner, Monika S. Kowalczyk, Lloyd Bod, Yoon-Chul Kye, Peter T. Sage, Arlene H. Sharpe, Raymond A. Sobel, Francisco J. Quintana, Orit Rozenblatt-Rosen, Aviv Regev, Chao Wang, Nir Yosef and Vijay K. Kuchroo
    J Immunol December 15, 2020, 205 (12) 3247-3262; DOI: https://doi.org/10.4049/jimmunol.2000748
  • T–B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein
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    T–B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein
    Rachel H. Bonami, Lindsay E. Nyhoff, Dudley H. McNitt, Chrys Hulbert, Jamie L. Felton, Peggy L. Kendall and James W. Thomas
    J Immunol December 15, 2020, 205 (12) 3263-3276; DOI: https://doi.org/10.4049/jimmunol.1900464
  • Open Access
    Screening of a Panel of Low Molecular Weight Compounds That Inhibit Synovial Fibroblast Invasion in Rheumatoid Arthritis

    Author Choice Article

    Tomoko Sugiura, Hiroki Kamino, Yuko Nariai, Yohko Murakawa, Masahiro Kondo, Makoto Kawakami, Noboru Ikeda, Yuji Uchio and Takeshi Urano
    J Immunol December 15, 2020, 205 (12) 3277-3290; DOI: https://doi.org/10.4049/jimmunol.1901429

CLINICAL AND HUMAN IMMUNOLOGY

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    A Sequential Two-Step Cell-Based Assay Predicts Immunosuppression-Related Adverse Events
    François Bouchard-Boivin, Olivier Désy, Stéphanie Béland, Alcino Gama, Isabelle Lapointe, Julie Lesage, Isabelle Côté, Narcisse Singbo, Isabelle Houde and Sacha A. De Serres
    J Immunol December 15, 2020, 205 (12) 3291-3299; DOI: https://doi.org/10.4049/jimmunol.2000782

IMMUNE REGULATION

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    GEF-H1 Is Required for Colchicine Inhibition of Neutrophil Rolling and Recruitment in Mouse Models of Gout
    Noah Fine, Eric Gracey, Ioannis Dimitriou, José La Rose, Michael Glogauer and Robert Rottapel
    J Immunol December 15, 2020, 205 (12) 3300-3310; DOI: https://doi.org/10.4049/jimmunol.1900783
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    The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation
    Mohammad Kamran, Jinyi Liang, Bing Liu, Yapeng Li, Junfeng Gao, Ashley Keating, Fathia Mohamed, Shaodong Dai, Richard Reinhardt, Yang Jiong, Zhongdao Wu and Hua Huang
    J Immunol December 15, 2020, 205 (12) 3311-3318; DOI: https://doi.org/10.4049/jimmunol.2000985

IMMUNOGENETICS

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    Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses
    Michael W. Grunst, Andres G. Grandea III, Sanath Kumar Janaka, Iman Hammad, Parker Grimes, Julie A. Karl, Roger Wiseman, David H. O’Connor and David T. Evans
    J Immunol December 15, 2020, 205 (12) 3319-3332; DOI: https://doi.org/10.4049/jimmunol.2000501

IMMUNOTHERAPY AND VACCINES

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    Essential Role of Neutrophils in the Protective Immune Response Induced by a Live Attenuated Leishmania Vaccine
    Parna Bhattacharya, Ranadhir Dey, Ankit Saxena, Subir Karmakar, Nevien Ismail, Sreenivas Gannavaram, Pradeep K. Dagur, Monika Satoskar, Sanika Satoskar, Silvia De Paoli, Kazuyo Takeda, John Philip McCoy Jr. and Hira L. Nakhasi
    J Immunol December 15, 2020, 205 (12) 3333-3347; DOI: https://doi.org/10.4049/jimmunol.2000829
  • Open Access
    TL1A–DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1–Specific T Cell Responses

    Author Choice Article

    Bruna Oriol-Tordera, Alex Olvera, Clara Duran-Castells, Anuska Llano, Beatriz Mothe, Marta Massanella, Judith Dalmau, Carmela Ganoza, Jorge Sanchez, Maria Luz Calle, Bonaventura Clotet, Javier Martinez-Picado, Eugènia Negredo, Julià Blanco, Dennis Hartigan-O'Connor, Christian Brander and Marta Ruiz-Riol
    J Immunol December 15, 2020, 205 (12) 3348-3357; DOI: https://doi.org/10.4049/jimmunol.2000933

INFECTIOUS DISEASE AND HOST RESPONSE

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    CD28 Agonism Improves Survival in Immunologically Experienced Septic Mice via IL-10 Released by Foxp3+ Regulatory T Cells
    Yini Sun, Jianfeng Xie, Jerome C. Anyalebechi, Ching-wen Chen, He Sun, Ming Xue, Zhe Liang, Kristen N. Morrow, Craig M. Coopersmith and Mandy L. Ford
    J Immunol December 15, 2020, 205 (12) 3358-3371; DOI: https://doi.org/10.4049/jimmunol.2000595
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    Control of B Cell Lymphoma by Gammaherpesvirus-Induced Memory CD8 T Cells
    Nicholas K. Preiss, Taewook Kang, Young-Kwang Usherwood, Yina H. Huang, Bruce R. Branchini and Edward J. Usherwood
    J Immunol December 15, 2020, 205 (12) 3372-3382; DOI: https://doi.org/10.4049/jimmunol.2000734
  • Innate Immune Memory to Repeated <em>Borrelia burgdorferi</em> Exposure Correlates with Murine In Vivo Inflammatory Phenotypes
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    Innate Immune Memory to Repeated Borrelia burgdorferi Exposure Correlates with Murine In Vivo Inflammatory Phenotypes
    Quentin Bernard and Linden T. Hu
    J Immunol December 15, 2020, 205 (12) 3383-3389; DOI: https://doi.org/10.4049/jimmunol.2000686

INNATE IMMUNITY AND INFLAMMATION

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    Overexpression of Macrophage-Inducible C-Type Lectin Mincle Aggravates Proinflammatory Responses to Streptococcus pneumoniae with Fatal Outcome in Mice
    Femke D. Hollwedel, Regina Maus, Jennifer Stolper, Ayesha Khan, Bridget L. Stocker, Mattie S. M. Timmer, Xiuyuan Lu, Andreas Pich, Tobias Welte, Sho Yamasaki and Ulrich A. Maus
    J Immunol December 15, 2020, 205 (12) 3390-3399; DOI: https://doi.org/10.4049/jimmunol.2000509
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    IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming
    Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, Sebastiaan A. J. Zaat, Michel van Weeghel, Dominique L. P. Baeten, Riekelt H. Houtkooper, Bart Everts, Gestur Vidarsson and Jeroen den Dunnen
    J Immunol December 15, 2020, 205 (12) 3400-3407; DOI: https://doi.org/10.4049/jimmunol.2000263
  • NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor
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    NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor
    Boyue Sun, Haoyang Zeng, Jiaqian Liang, Lele Zhang, Haiyang Hu, Quanyi Wang, Wei Meng, Chenhui Li, Fuqiang Ye, Chen Wang and Juanjuan Zhu
    J Immunol December 15, 2020, 205 (12) 3408-3418; DOI: https://doi.org/10.4049/jimmunol.1901455
  • <em>Tupaia</em> OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS
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    Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS
    Yu-Lin Yao, Dandan Yu, Ling Xu, Tianle Gu, Yu Li, Xiao Zheng, Rui Bi and Yong-Gang Yao
    J Immunol December 15, 2020, 205 (12) 3419-3428; DOI: https://doi.org/10.4049/jimmunol.2000740
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    IL-18 Responsiveness Defines Limitations in Immune Help for Specialized FcRγ– NK Cells
    Renee R. Anderko, Charles R. Rinaldo and Robbie B. Mailliard
    J Immunol December 15, 2020, 205 (12) 3429-3442; DOI: https://doi.org/10.4049/jimmunol.2000430
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    Mannose-Binding Lectin Possesses Agglutination Activity and Promotes Opsonophagocytosis of Macrophages with Calreticulin Interaction in an Early Vertebrate
    Liangliang Mu, Xiaoxue Yin, Hairong Wu, Yang Lei, Kailiang Han, Jinfeng Mo, Zheng Guo, Jun Li and Jianmin Ye
    J Immunol December 15, 2020, 205 (12) 3443-3455; DOI: https://doi.org/10.4049/jimmunol.2000256

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Glycine 236 in the Lower Hinge Region of Human IgG1 Differentiates FcγR from Complement Effector Function
    Maximilian Brinkhaus, Ruben G. J. Douwes, Arthur E. H. Bentlage, A. Robin Temming, Steven W. de Taeye, Matthias Tammes Buirs, Jacoline Gerritsen, Juk Yee Mok, Giso Brasser, Peter C. Ligthart, Wim J. E. van Esch, Peter Verheesen, Hans de Haard, Theo Rispens and Gestur Vidarsson
    J Immunol December 15, 2020, 205 (12) 3456-3467; DOI: https://doi.org/10.4049/jimmunol.2000961

SYSTEMS IMMUNOLOGY

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    Position-Dependent Differential Targeting of Somatic Hypermutation
    Julian Q. Zhou and Steven H. Kleinstein
    J Immunol December 15, 2020, 205 (12) 3468-3479; DOI: https://doi.org/10.4049/jimmunol.2000496

TRANSPLANTATION

  • Kras-Deficient T Cells Attenuate Graft-versus-Host Disease but Retain Graft-versus-Leukemia Activity
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    Kras-Deficient T Cells Attenuate Graft-versus-Host Disease but Retain Graft-versus-Leukemia Activity
    Lan Luo, Yuhong Chen, Xiao Chen, Yongwei Zheng, Vivian Zhou, Mei Yu, Robert Burns, Wen Zhu, Guoping Fu, Juan C. Felix, Christopher Hartley, Alisa Damnernsawad, Jing Zhang, Renren Wen, Williams R. Drobyski, Chunji Gao and Demin Wang
    J Immunol December 15, 2020, 205 (12) 3480-3490; DOI: https://doi.org/10.4049/jimmunol.2000006

NOVEL IMMUNOLOGICAL METHODS

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    Development of a SARS-CoV-2 Total Antibody Assay and the Dynamics of Antibody Response over Time in Hospitalized and Nonhospitalized Patients with COVID-19
    Erik H. Vogelzang, Floris C. Loeff, Ninotska I. L. Derksen, Simone Kruithof, Pleuni Ooijevaar-de Heer, Gerard van Mierlo, Federica Linty, Juk Yee Mok, Wim van Esch, Sanne de Bruin, Alexander P. J. Vlaar, Bart Seppen, Maureen Leeuw, Anne J. G. van Oudheusden, Anton G. M. Buiting, Kin Ki Jim, Hans Vrielink, Francis Swaneveld, Gestur Vidarsson, C. Ellen van der Schoot, Peter C. Wever, Wentao Li, Frank van Kuppeveld, Jean-Luc Murk, Berend Jan Bosch, Gerrit-Jan Wolbink and Theo Rispens
    J Immunol December 15, 2020, 205 (12) 3491-3499; DOI: https://doi.org/10.4049/jimmunol.2000767
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This Issue

The Journal of Immunology: 205 (12)
The Journal of Immunology
Vol. 205, Issue 12
15 Dec 2020
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)

Issue highlights

  • Top Reads
  • A Case for Phosphoinositide 3-Kinase–Targeted Therapy for Infectious Disease
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  • TOP READS
  • BRIEF REVIEWS
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNOGENETICS
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • SYSTEMS IMMUNOLOGY
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  • NOVEL IMMUNOLOGICAL METHODS
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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