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The Journal of Immunology

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Table of Contents

June 15, 2020; Volume 204,Issue 12

TOP READS

  • You have accessRestricted access
    Top Reads

    Adjuvant Properties of Endogenous Phospholipase A2 See article p. 3097

    miR-21 Controls Glycolysis of Pathogenic TH17 Cells See article p. 3160

    UHRF1 Controls Thymocyte Fate Decisions via EGR1 See article p. 3248

    Bmi1 Maintains B-1 Cell Self-Renewal Ability See article p. 3262

    IL-1R Tolerance and Cachexia in Toxoplasma gondii infection See article p. 3329

    Anti-Inflammatory Effects of Δ9-THC See article p. 3339

    Regulation of MDSCs by MLL1 See article p. 3400

    J Immunol June 15, 2020, 204 (12) 3061-3062; DOI: https://doi.org/10.4049/jimmunol.2090008

BRIEF REVIEWS

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    Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
    Sampsa Matikainen, Tuula A. Nyman and Wojciech Cypryk
    J Immunol June 15, 2020, 204 (12) 3063-3069; DOI: https://doi.org/10.4049/jimmunol.2000373

CUTTING EDGE

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    Cutting Edge: ST8Sia6-Generated α-2,8-Disialic Acids Mitigate Hyperglycemia in Multiple Low-Dose Streptozotocin–Induced Diabetes
    Paul J. Belmonte, Michael J. Shapiro, Matthew J. Rajcula, Shaylene A. McCue and Virginia Smith Shapiro
    J Immunol June 15, 2020, 204 (12) 3071-3076; DOI: https://doi.org/10.4049/jimmunol.2000023

ALLERGY AND OTHER HYPERSENSITIVITIES

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    Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation
    Kazuki Yoshida, Masa-aki Ito, Naoko Sato, Kosuke Obayashi, Kimiko Yamamoto, Schuichi Koizumi, Satoshi Tanaka, Kazuyuki Furuta and Isao Matsuoka
    J Immunol June 15, 2020, 204 (12) 3077-3085; DOI: https://doi.org/10.4049/jimmunol.1900954
  • Group 2 Innate Lymphoid Cells Promote Development of T Follicular Helper Cells and Initiate Allergic Sensitization to Peanuts
    Open Access
    Group 2 Innate Lymphoid Cells Promote Development of T Follicular Helper Cells and Initiate Allergic Sensitization to Peanuts

    Author Choice Article

    James W. Krempski, Takao Kobayashi, Koji Iijima, Andrew N. McKenzie and Hirohito Kita
    J Immunol June 15, 2020, 204 (12) 3086-3096; DOI: https://doi.org/10.4049/jimmunol.2000029
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    Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung
    Herbert Luke Ogden, Ying Lai, James D. Nolin, Dowon An, Charles W. Frevert, Michael H. Gelb, William A. Altemeier and Teal S. Hallstrand
    J Immunol June 15, 2020, 204 (12) 3097-3107; DOI: https://doi.org/10.4049/jimmunol.2000102

ANTIGEN RECOGNITION AND RESPONSES

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    The Impact of MHC Class I Dose on Development and Maintenance of the Polyclonal Naive CD8+ T Cell Repertoire
    Xavier Y. X. Sng, Jasmine Li, Pirooz Zareie, Lisa M. Assmus, Jason K. C. Lee, Claerwen M. Jones, Stephen J. Turner, Stephen R. Daley, Kylie M. Quinn and Nicole L. La Gruta
    J Immunol June 15, 2020, 204 (12) 3108-3116; DOI: https://doi.org/10.4049/jimmunol.2000081

AUTOIMMUNITY

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    Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease
    Manoj Thapa, Dana Tedesco, Sanjeev Gumber, Elizabeth J. Elrod, Jin-Hwan Han, William H. Kitchens, Joseph F. Magliocca, Andrew B. Adams and Arash Grakoui
    J Immunol June 15, 2020, 204 (12) 3117-3128; DOI: https://doi.org/10.4049/jimmunol.1900391
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    Costimulation Blockade Disrupts CD4+ T Cell Memory Pathways and Uncouples Their Link to Decline in β-Cell Function in Type 1 Diabetes
    Martin Eichmann, Roman Baptista, Richard J. Ellis, Susanne Heck, Mark Peakman and Craig A. Beam
    J Immunol June 15, 2020, 204 (12) 3129-3138; DOI: https://doi.org/10.4049/jimmunol.1901439

CLINICAL AND HUMAN IMMUNOLOGY

  • GPA33: A Marker to Identify Stable Human Regulatory T Cells
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    GPA33: A Marker to Identify Stable Human Regulatory T Cells
    Rianne Opstelten, Sander de Kivit, Manon C. Slot, Maartje van den Biggelaar, Dorota Iwaszkiewicz-Grześ, Mateusz Gliwiński, Andrew M. Scott, Bianca Blom, Piotr Trzonkowski, Jannie Borst, Eloy Cuadrado and Derk Amsen
    J Immunol June 15, 2020, 204 (12) 3139-3148; DOI: https://doi.org/10.4049/jimmunol.1901250
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    Human Term Pregnancy Decidual NK Cells Generate Distinct Cytotoxic Responses
    Ricardo de Mendonça Vieira, Ava Meagher, Ângela C. Crespo, Sarika K. Kshirsagar, Vidya Iyer, Errol R. Norwitz, Jack L. Strominger and Tamara Tilburgs
    J Immunol June 15, 2020, 204 (12) 3149-3159; DOI: https://doi.org/10.4049/jimmunol.1901435

IMMUNE REGULATION

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    Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR-21–Peli1–c-Rel Pathway Prevents Autoimmunity
    Rong Qiu, Xiang Yu, Li Wang, Zhijun Han, Chao Yao, Yange Cui, Guojun Hou, Dai Dai, Wenfei Jin and Nan Shen
    J Immunol June 15, 2020, 204 (12) 3160-3170; DOI: https://doi.org/10.4049/jimmunol.2000060
  • TGF-β and IL-15 Synergize through MAPK Pathways to Drive the Conversion of Human NK Cells to an Innate Lymphoid Cell 1–like Phenotype
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    TGF-β and IL-15 Synergize through MAPK Pathways to Drive the Conversion of Human NK Cells to an Innate Lymphoid Cell 1–like Phenotype
    Lindsey G. Hawke, Brandon Z. Mitchell and Mark L. Ormiston
    J Immunol June 15, 2020, 204 (12) 3171-3181; DOI: https://doi.org/10.4049/jimmunol.1900866
  • Open Access
    Genome-Wide DNA Methylation and RNA Analysis Reveal Potential Mechanism of Resistance to Streptococcus agalactiae in GIFT Strain of Nile Tilapia (Oreochromis niloticus)

    Author Choice Article

    Qiaomu Hu, Qiuwei Ao, Yun Tan, Xi Gan, Yongju Luo and Jiajie Zhu
    J Immunol June 15, 2020, 204 (12) 3182-3190; DOI: https://doi.org/10.4049/jimmunol.1901496
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    An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3
    Ling Xu, Dandan Yu, Li Peng, Yong Wu, Yu Fan, Tianle Gu, Yu-Lin Yao, Jin Zhong, Xinwen Chen and Yong-Gang Yao
    J Immunol June 15, 2020, 204 (12) 3191-3204; DOI: https://doi.org/10.4049/jimmunol.1901320
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    Intravenous Infusion of Cortisol, Adrenaline, or Noradrenaline Alters Porcine Immune Cell Numbers and Promotes Innate over Adaptive Immune Functionality
    Lena Reiske, Sonja Schmucker, Birgit Pfaffinger, Ulrike Weiler, Julia Steuber and Volker Stefanski
    J Immunol June 15, 2020, 204 (12) 3205-3216; DOI: https://doi.org/10.4049/jimmunol.2000269
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    Endogenous CD83 Expression in CD4+ Conventional T Cells Controls Inflammatory Immune Responses
    Katarina Liedtke, Christina Alter, Anne Günther, Nadine Hövelmeyer, Robert Klopfleisch, Ronald Naumann, F. Thomas Wunderlich, Jan Buer, Astrid M. Westendorf and Wiebke Hansen
    J Immunol June 15, 2020, 204 (12) 3217-3226; DOI: https://doi.org/10.4049/jimmunol.2000042
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    The Abundance and Availability of Cytokine Receptor IL-2Rβ (CD122) Constrain the Lymphopenia-Induced Homeostatic Proliferation of Naive CD4 T Cells
    Hilary R. Keller, Hye Kyung Kim, Yuna Jo, Ronald E. Gress, Changwan Hong and Jung-Hyun Park
    J Immunol June 15, 2020, 204 (12) 3227-3235; DOI: https://doi.org/10.4049/jimmunol.1901276
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    Rapid Death of Follicular B Cells and Burkitt Lymphoma Cells Effectuated by Xbp1s
    Yi-Ting Chen and John T. Kung
    J Immunol June 15, 2020, 204 (12) 3236-3247; DOI: https://doi.org/10.4049/jimmunol.2000172

IMMUNE SYSTEM DEVELOPMENT

  • UHRF1 Controls Thymocyte Fate Decisions through the Epigenetic Regulation of EGR1 Expression
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    UHRF1 Controls Thymocyte Fate Decisions through the Epigenetic Regulation of EGR1 Expression
    Yiwen Zhang, Yingshi Chen, Rong Ma, Yawen Jiang, Jun Liu, Yingtong Lin, Siqi Chen, Mengying Xia, Fan Zou, Junsong Zhang, Ting Pan, Lie Wang, Lai Wei and Hui Zhang
    J Immunol June 15, 2020, 204 (12) 3248-3261; DOI: https://doi.org/10.4049/jimmunol.1901471
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    Bmi1 Maintains the Self-Renewal Property of Innate-like B Lymphocytes
    Michihiro Kobayashi, Yang Lin, Akansha Mishra, Chris Shelly, Rui Gao, Colton W. Reeh, Paul Zhiping Wang, Rongwen Xi, Yunlong Liu, Pamela Wenzel, Eliver Ghosn, Yan Liu and Momoko Yoshimoto
    J Immunol June 15, 2020, 204 (12) 3262-3272; DOI: https://doi.org/10.4049/jimmunol.2000030

IMMUNOGENETICS

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    Immunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies
    Peter van Balen, Michel G. D. Kester, Wendy de Klerk, Pietro Crivello, Esteban Arrieta-Bolaños, Arnoud H. de Ru, Inge Jedema, Yassene Mohammed, Mirjam H. M. Heemskerk, Katharina Fleischhauer, Peter A. van Veelen and J. H. Frederik Falkenburg
    J Immunol June 15, 2020, 204 (12) 3273-3282; DOI: https://doi.org/10.4049/jimmunol.2000192

IMMUNOTHERAPY AND VACCINES

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    Therapeutic CMP-Nonulosonates against Multidrug-Resistant Neisseria gonorrhoeae
    Sunita Gulati, Ian C. Schoenhofen, Theresa Lindhout-Djukic, Melissa J. Schur, Corinna S. Landig, Sudeshna Saha, Lingquan Deng, Lisa A. Lewis, Bo Zheng, Ajit Varki and Sanjay Ram
    J Immunol June 15, 2020, 204 (12) 3283-3295; DOI: https://doi.org/10.4049/jimmunol.1901398
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    CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection
    Althea Campuzano, Hao Zhang, Gary R. Ostroff, Lucas dos Santos Dias, Marcel Wüthrich, Bruce S. Klein, Jieh-Juen Yu, Humberto H. Lara, Jose L. Lopez-Ribot and Chiung-Yu Hung
    J Immunol June 15, 2020, 204 (12) 3296-3306; DOI: https://doi.org/10.4049/jimmunol.1900793

INFECTIOUS DISEASE AND HOST RESPONSE

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    CD25-Targeted IL-2 Signals Promote Improved Outcomes of Influenza Infection and Boost Memory CD4 T Cell Formation
    Fahmida Alam, Ayushi Singh, Valeria Flores-Malavet, Stewart Sell, Andrea M. Cooper, Susan L. Swain, K. Kai McKinstry and Tara M. Strutt
    J Immunol June 15, 2020, 204 (12) 3307-3314; DOI: https://doi.org/10.4049/jimmunol.2000205
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    An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes
    Sabrina Helmold Hait, Christopher James Hogge, Mohammad Arif Rahman, Eun-Ju Ko, Ruth Hunegnaw, Zuena Mushtaq, Gospel Enyindah-Asonye, Tanya Hoang, Lisa M. Miller Jenkins, Ettore Appella, Daniel H. Appella and Marjorie Robert-Guroff
    J Immunol June 15, 2020, 204 (12) 3315-3328; DOI: https://doi.org/10.4049/jimmunol.2000165

INNATE IMMUNITY AND INFLAMMATION

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    IL-1R Regulates Disease Tolerance and Cachexia in Toxoplasma gondii Infection
    Stephanie J. Melchor, Claire M. Saunders, Imani Sanders, Jessica A. Hatter, Kari A. Byrnes, Sheryl Coutermarsh-Ott and Sarah E. Ewald
    J Immunol June 15, 2020, 204 (12) 3329-3338; DOI: https://doi.org/10.4049/jimmunol.2000159
  • Activation of CB<sub>1</sub>R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury
    Open Access
    Activation of CB1R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury

    Author Choice Article

    Jérémie Joffre, Che-Chung Yeh, Erika Wong, Mayuri Thete, Fengyun Xu, Ivana Zlatanova, Elliot Lloyd, Lester Kobzik, Matthieu Legrand and Judith Hellman
    J Immunol June 15, 2020, 204 (12) 3339-3350; DOI: https://doi.org/10.4049/jimmunol.2000213

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Structure of MHC-Independent TCRs and Their Recognition of Native Antigen CD155
    Jinghua Lu, François Van Laethem, Ingrid Saba, Jonathan Chu, Anastasia N. Tikhonova, Abhisek Bhattacharya, Alfred Singer and Peter D. Sun
    J Immunol June 15, 2020, 204 (12) 3351-3359; DOI: https://doi.org/10.4049/jimmunol.1901084
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    Cullin 3 Is Crucial for Pro-B Cell Proliferation, Interacts with CD22, and Controls CD22 Internalization on B Cells
    Sarah J. Meyer, Alexander Böser, Marina A. Korn, Claudia Koller, Barbara Bertocci, Lena Reimann, Bettina Warscheid and Lars Nitschke
    J Immunol June 15, 2020, 204 (12) 3360-3374; DOI: https://doi.org/10.4049/jimmunol.1900925

SYSTEMS IMMUNOLOGY

  • Open Access
    Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination

    Author Choice Article

    Lucille Adam, Nicolas Tchitchek, Biliana Todorova, Pierre Rosenbaum, Candie Joly, Candice Poux, Catherine Chapon, Anna-Lena Spetz, Mart Ustav, Roger Le Grand and Frédéric Martinon
    J Immunol June 15, 2020, 204 (12) 3375-3388; DOI: https://doi.org/10.4049/jimmunol.1900517
  • Open Access
    Distinct Features of Human Myeloid Cell Cytokine Response Profiles Identify Neutrophil Activation by Cytokines as a Prognostic Feature during Tuberculosis and Cancer

    Author Choice Article

    Joseph C. Devlin, Erin E. Zwack, Mei San Tang, Zhi Li, David Fenyo, Victor J. Torres, Kelly V. Ruggles and P’ng Loke
    J Immunol June 15, 2020, 204 (12) 3389-3399; DOI: https://doi.org/10.4049/jimmunol.1901133

TUMOR IMMUNOLOGY

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    Suppression of Mll1-Complex by Stat3/Cebpβ–Induced miR-21a/21b/181b Maintains the Accumulation, Homeostasis, and Immunosuppressive Function of Polymorphonuclear Myeloid-Derived Suppressor Cells
    Zhiqian Zhang, Xu Huang, Enlin Wang, Yugang Huang and Rongcun Yang
    J Immunol June 15, 2020, 204 (12) 3400-3415; DOI: https://doi.org/10.4049/jimmunol.2000230
  • Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy
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    Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy
    Tiffany C. Blair, Shelly Bambina, Alejandro F. Alice, Gwen F. Kramer, Terry R. Medler, Jason R. Baird, Miranda L. Broz, Garth W. Tormoen, Victoria Troesch, Marka R. Crittenden and Michael J. Gough
    J Immunol June 15, 2020, 204 (12) 3416-3424; DOI: https://doi.org/10.4049/jimmunol.2000194

NOVEL IMMUNOLOGICAL METHODS

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    A Novel Utility to Correct for Plate/Batch/Lot and Nonspecific Binding Artifacts in Luminex Data
    Holden T. Maecker, Yael Rosenberg-Hasson, Kathleen Durgin Kolstad, Virginia D. Steen and Lorinda S. Chung
    J Immunol June 15, 2020, 204 (12) 3425-3433; DOI: https://doi.org/10.4049/jimmunol.2000017
  • Open Access
    Systematic Profiling of Full-Length Ig and TCR Repertoire Diversity in Rhesus Macaque through Long Read Transcriptome Sequencing

    Author Choice Article

    Hayden N. Brochu, Elizabeth Tseng, Elise Smith, Matthew J. Thomas, Aiden M. Jones, Kayleigh R. Diveley, Lynn Law, Scott G. Hansen, Louis J. Picker, Michael Gale Jr. and Xinxia Peng
    J Immunol June 15, 2020, 204 (12) 3434-3444; DOI: https://doi.org/10.4049/jimmunol.1901256
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This Issue

The Journal of Immunology: 204 (12)
The Journal of Immunology
Vol. 204, Issue 12
15 Jun 2020
  • Table of Contents
  • Table of Contents (PDF)
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  • Advertising (PDF)
  • Back Matter (PDF)
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  • Front Matter (PDF)

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  • Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
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  • TOP READS
  • BRIEF REVIEWS
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
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  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNE SYSTEM DEVELOPMENT
  • IMMUNOGENETICS
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • SYSTEMS IMMUNOLOGY
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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