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IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis

Hannes Lindahl, André O. Guerreiro-Cacais, Sahl Khalid Bedri, Mathias Linnerbauer, Magdalena Lindén, Nada Abdelmagid, Karolina Tandre, Claire Hollins, Lorraine Irving, Colin Glover, Clare Jones, Lars Alfredsson, Lars Rönnblom, Ingrid Kockum, Mohsen Khademi, Maja Jagodic and Tomas Olsson
J Immunol August 15, 2019, 203 (4) 888-898; DOI: https://doi.org/10.4049/jimmunol.1900400
Hannes Lindahl
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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  • ORCID record for Hannes Lindahl
André O. Guerreiro-Cacais
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Sahl Khalid Bedri
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Mathias Linnerbauer
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Magdalena Lindén
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Nada Abdelmagid
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Karolina Tandre
†Department of Medical Sciences, Rheumatology and Science for Life Laboratories, Uppsala University, 75105 Uppsala, Sweden;
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Claire Hollins
‡Respiratory, Inflammation and Autoimmunity Research, MedImmune, Cambridge CB21 6GH, United Kingdom;
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Lorraine Irving
§High Content Imaging, MedImmune, Cambridge CB21 6GH, United Kingdom; and
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Colin Glover
‡Respiratory, Inflammation and Autoimmunity Research, MedImmune, Cambridge CB21 6GH, United Kingdom;
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Clare Jones
‡Respiratory, Inflammation and Autoimmunity Research, MedImmune, Cambridge CB21 6GH, United Kingdom;
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Lars Alfredsson
¶Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden
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Lars Rönnblom
†Department of Medical Sciences, Rheumatology and Science for Life Laboratories, Uppsala University, 75105 Uppsala, Sweden;
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Ingrid Kockum
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Mohsen Khademi
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Maja Jagodic
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Tomas Olsson
*Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
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Article Information

vol. 203 no. 4 888-898
DOI 
https://doi.org/10.4049/jimmunol.1900400
PubMed 
31292217

Published By 
The American Association of Immunologists, Inc.
Print ISSN 
0022-1767
Online ISSN 
1550-6606
History 
  • Received April 10, 2019
  • Accepted June 18, 2019
  • Published online August 5, 2019.

Article Versions

  • Older version (July 10, 2019 - 08:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2019 by The American Association of Immunologists, Inc.

Author Information

  1. Hannes Lindahl*,
  2. André O. Guerreiro-Cacais*,
  3. Sahl Khalid Bedri*,
  4. Mathias Linnerbauer*,
  5. Magdalena Lindén*,
  6. Nada Abdelmagid*,
  7. Karolina Tandre†,
  8. Claire Hollins‡,
  9. Lorraine Irving§,
  10. Colin Glover‡,
  11. Clare Jones‡,
  12. Lars Alfredsson¶,
  13. Lars Rönnblom†,
  14. Ingrid Kockum*,
  15. Mohsen Khademi*,
  16. Maja Jagodic* and
  17. Tomas Olsson*
  1. *Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden;
  2. †Department of Medical Sciences, Rheumatology and Science for Life Laboratories, Uppsala University, 75105 Uppsala, Sweden;
  3. ‡Respiratory, Inflammation and Autoimmunity Research, MedImmune, Cambridge CB21 6GH, United Kingdom;
  4. §High Content Imaging, MedImmune, Cambridge CB21 6GH, United Kingdom; and
  5. ¶Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden
  1. Address correspondence and reprint requests to Dr. Hannes Lindahl, CMM L8:04, Karolinska University Hospital, 17176 Stockholm, Sweden. E-mail address: hannes.lindahl{at}ki.se
  1. H.L., A.O.G.-C., M.J., and T.O. contributed to experimental design. K.T. and N.A. performed sample collection. H.L., A.O.G.-C., S.K.B., M. Linnerbauer, M. Lindén, C.H., C.J., L.I., C.G., and M.K. performed experiments, data collection, and data analysis. H.L. wrote the manuscript. H.L., A.O.G.-C., S.K.B., M. Linnerbauer, M. Lindén, N.A., L.A., L.R., I.K., M.K., M.J., and T.O. edited the manuscript.

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Article usage

Article usage: July 2019 to December 2020

AbstractFullPdf
Jul 2019782587
Aug 201963615285
Sep 20191193721
Oct 2019813424
Nov 201982923
Dec 2019502117
Total 20191750258257
Jan 202072912
Feb 20204239
Mar 202037813
Apr 202080712
May 2020501015
Jun 20205677
Jul 202039314
Aug 2020112817
Sep 202081822
Oct 202072017
Nov 20201013221
Dec 20201020220
Total 2020422447179
Total2172705436

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The Journal of Immunology: 203 (4)
The Journal of Immunology
Vol. 203, Issue 4
15 Aug 2019
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IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis
Hannes Lindahl, André O. Guerreiro-Cacais, Sahl Khalid Bedri, Mathias Linnerbauer, Magdalena Lindén, Nada Abdelmagid, Karolina Tandre, Claire Hollins, Lorraine Irving, Colin Glover, Clare Jones, Lars Alfredsson, Lars Rönnblom, Ingrid Kockum, Mohsen Khademi, Maja Jagodic, Tomas Olsson
The Journal of Immunology August 15, 2019, 203 (4) 888-898; DOI: 10.4049/jimmunol.1900400

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IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis
Hannes Lindahl, André O. Guerreiro-Cacais, Sahl Khalid Bedri, Mathias Linnerbauer, Magdalena Lindén, Nada Abdelmagid, Karolina Tandre, Claire Hollins, Lorraine Irving, Colin Glover, Clare Jones, Lars Alfredsson, Lars Rönnblom, Ingrid Kockum, Mohsen Khademi, Maja Jagodic, Tomas Olsson
The Journal of Immunology August 15, 2019, 203 (4) 888-898; DOI: 10.4049/jimmunol.1900400
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