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Table of Contents

December 1, 2019; Volume 203,Issue 11

TOP READS

  • Open Access
    Top Reads
    The Journal of Immunology December 1, 2019, 203 (11) 2747-2748; DOI: https://doi.org/10.4049/jimmunol.1990021

TRANSLATING IMMUNOLOGY

  • Open Access
    Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases
    Maryam Tahvildari and Reza Dana
    The Journal of Immunology December 1, 2019, 203 (11) 2749-2755; DOI: https://doi.org/10.4049/jimmunol.1900733

BRIEF REVIEWS

  • Open Access
    Inflammasomes: Their Role in Normal and Complicated Pregnancies
    Nardhy Gomez-Lopez, Kenichiro Motomura, Derek Miller, Valeria Garcia-Flores, Jose Galaz and Roberto Romero
    The Journal of Immunology December 1, 2019, 203 (11) 2757-2769; DOI: https://doi.org/10.4049/jimmunol.1900901

CUTTING EDGE

  • Open Access
    Cutting Edge: TCR Signal Strength Regulates Acetyl-CoA Metabolism via AKT
    William F. Hawse, Richard T. Cattley and Stacy G. Wendell
    The Journal of Immunology December 1, 2019, 203 (11) 2771-2775; DOI: https://doi.org/10.4049/jimmunol.1900749

ALLERGY AND OTHER HYPERSENSITIVITIES

  • Open Access
    Inhibition of Allergic Reactivity through Targeting FcεRI-Bound IgE with Humanized Low-Affinity Antibodies
    Ke Zhang, Michael Elias, Hong Zhang, Jeffrey Liu, Christopher Kepley, Yun Bai, Dean D. Metcalfe, Zachary Schiller, Yang Wang and Andrew Saxon
    The Journal of Immunology December 1, 2019, 203 (11) 2777-2790; DOI: https://doi.org/10.4049/jimmunol.1900112

AUTOIMMUNITY

  • Open Access
    Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell–Mediated Autoimmunity
    Kea Martin, Ratiba Touil, Yeter Kolb, Grozdan Cvijetic, Kiichi Murakami, Laura Israel, Fernanda Duraes, David Buffet, Anton Glück, Satoru Niwa, Marc Bigaud, Tobias Junt, Natasa Zamurovic, Philip Smith, Kathy D. McCoy, Pamela S. Ohashi, Frédéric Bornancin and Thomas Calzascia
    The Journal of Immunology December 1, 2019, 203 (11) 2791-2806; DOI: https://doi.org/10.4049/jimmunol.1900327
  • Open Access
    cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus
    Sigrun R. Hofmann, Katrin Mäbert, Franz Kapplusch, Susanne Russ, Sarah Northey, Michael W. Beresford, George C. Tsokos and Christian M. Hedrich
    The Journal of Immunology December 1, 2019, 203 (11) 2807-2816; DOI: https://doi.org/10.4049/jimmunol.1900760
  • Open Access
    Functional Characterization of CD11c+ Age-Associated B Cells as Memory B Cells
    Samuel W. Du, Tanvi Arkatkar, Fahd Al Qureshah, Holly M. Jacobs, Christopher D. Thouvenel, Kristy Chiang, Andrea D. Largent, Quan-Zhen Li, Baidong Hou, David J. Rawlings and Shaun W. Jackson
    The Journal of Immunology December 1, 2019, 203 (11) 2817-2826; DOI: https://doi.org/10.4049/jimmunol.1900404
  • Open Access
    UBASH3A Regulates the Synthesis and Dynamics of TCR–CD3 Complexes
    Yan Ge, Taylor K. Paisie, Sixue Chen and Patrick Concannon
    The Journal of Immunology December 1, 2019, 203 (11) 2827-2836; DOI: https://doi.org/10.4049/jimmunol.1801338
  • Open Access
    TNF-Induced Interstitial Lung Disease in a Murine Arthritis Model: Accumulation of Activated Monocytes, Conventional Dendritic Cells, and CD21+/CD23− B Cell Follicles Is Prevented with Anti-TNF Therapy
    Emily K. Wu, Zoe I. Henkes, Brion McGowan, Richard D. Bell, Moises J. Velez, Alexandra M. Livingstone, Christopher T. Ritchlin, Edward M. Schwarz and Homaira Rahimi
    The Journal of Immunology December 1, 2019, 203 (11) 2837-2849; DOI: https://doi.org/10.4049/jimmunol.1900473

IMMUNE REGULATION

  • Open Access
    Regulatory T Cell Transmigration and Intravascular Migration Undergo Mechanistically Distinct Regulation at Different Phases of the Inflammatory Response
    Sarah L. Snelgrove, Latasha D. Abeynaike, Sukarnan Thevalingam, James A. Deane and Michael J. Hickey
    The Journal of Immunology December 1, 2019, 203 (11) 2850-2861; DOI: https://doi.org/10.4049/jimmunol.1900447
  • Open Access
    RELMα Licenses Macrophages for Damage-Associated Molecular Pattern Activation to Instigate Pulmonary Vascular Remodeling
    Qing Lin, Chunling Fan, John T. Skinner, Elizabeth N. Hunter, Andrew A. Macdonald, Peter B. Illei, Kazuyo Yamaji-Kegan and Roger A. Johns
    The Journal of Immunology December 1, 2019, 203 (11) 2862-2871; DOI: https://doi.org/10.4049/jimmunol.1900535
  • Open Access
    TLR2 Stimulation Increases Cellular Metabolism in CD8+ T Cells and Thereby Enhances CD8+ T Cell Activation, Function, and Antiviral Activity
    Ejuan Zhang, Zhiyong Ma, Qian Li, Hu Yan, Jia Liu, Weimin Wu, Jiabao Guo, Xiaoyong Zhang, Carsten J. Kirschning, Haifeng Xu, Philipp A. Lang, Dongliang Yang, Ulf Dittmer, Huimin Yan and Mengji Lu
    The Journal of Immunology December 1, 2019, 203 (11) 2872-2886; DOI: https://doi.org/10.4049/jimmunol.1900065
  • Open Access
    Downregulation of MHC Class II by Ubiquitination Is Required for the Migration of CD206+ Dendritic Cells to Skin-Draining Lymph Nodes
    Abdelilah Majdoubi, Jun Seong Lee, Mohammad Balood, Antoine Sabourin, Auriane DeMontigny, Osama A. Kishta, Mohamed Abdelwafi Moulefera, Tristan Galbas, Tae Jin Yun, Sébastien Talbot, Satoshi Ishido, Cheolho Cheong and Jacques Thibodeau
    The Journal of Immunology December 1, 2019, 203 (11) 2887-2898; DOI: https://doi.org/10.4049/jimmunol.1900593

IMMUNE SYSTEM DEVELOPMENT

  • Open Access
    Folliculin Interacting Protein 1 Maintains Metabolic Homeostasis during B Cell Development by Modulating AMPK, mTORC1, and TFE3
    Julita A. Ramírez, Terri Iwata, Heon Park, Mark Tsang, Janella Kang, Katy Cui, Winnie Kwong, Richard G. James, Masaya Baba, Laura S. Schmidt and Brian M. Iritani
    The Journal of Immunology December 1, 2019, 203 (11) 2899-2908; DOI: https://doi.org/10.4049/jimmunol.1900395

IMMUNOGENETICS

  • Open Access
    Ancient BCMA-like Genes Herald B Cell Regulation in Lampreys
    Sabyasachi Das, Yoichi Sutoh, Michael P. Cancro, Jonathan P. Rast, Qifeng Han, Gayathri Bommakanti, Max D. Cooper and Masayuki Hirano
    The Journal of Immunology December 1, 2019, 203 (11) 2909-2916; DOI: https://doi.org/10.4049/jimmunol.1900026

IMMUNOTHERAPY AND VACCINES

  • Open Access
    MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria
    Sara Suliman, Melissa Murphy, Munyaradzi Musvosvi, Anele Gela, Erin W. Meermeier, Hennie Geldenhuys, Christiaan Hopley, Asma Toefy, Nicole Bilek, Ashley Veldsman, Willem A. Hanekom, John L. Johnson, W. Henry Boom, Gerlinde Obermoser, Huang Huang, Mark Hatherill, David M. Lewinsohn, Elisa Nemes and Thomas J. Scriba
    The Journal of Immunology December 1, 2019, 203 (11) 2917-2927; DOI: https://doi.org/10.4049/jimmunol.1900674

INFECTIOUS DISEASE AND HOST RESPONSE

  • Open Access
    Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency Virus Infection in Rhesus Macaques
    Afam A. Okoye, Maren Q. DeGottardi, Yoshinori Fukazawa, Mukta Vaidya, Chike O. Abana, Audrie L. Konfe, Devin N. Fachko, Derick M. Duell, He Li, Richard Lum, Lina Gao, Byung S. Park, Rebecca L. Skalsky, Anne D. Lewis, Michael K. Axthelm, Jeffrey D. Lifson, Scott W. Wong and Louis J. Picker
    The Journal of Immunology December 1, 2019, 203 (11) 2928-2943; DOI: https://doi.org/10.4049/jimmunol.1900792
  • Open Access
    The IL-12– and IL-23–Dependent NK Cell Response Is Essential for Protective Immunity against Secondary Toxoplasma gondii Infection
    Daria L. Ivanova, Tiffany M. Mundhenke and Jason P. Gigley
    The Journal of Immunology December 1, 2019, 203 (11) 2944-2958; DOI: https://doi.org/10.4049/jimmunol.1801525
  • Open Access
    Multiple Signaling Pathways Involved in Human Dendritic Cell Maturation Are Affected by the Fungal Quorum-Sensing Molecule Farnesol
    Wolfgang Vivas, Ines Leonhardt, Kerstin Hünniger, Antje Häder, Alessandra Marolda and Oliver Kurzai
    The Journal of Immunology December 1, 2019, 203 (11) 2959-2969; DOI: https://doi.org/10.4049/jimmunol.1900431

INNATE IMMUNITY AND INFLAMMATION

  • Open Access
    The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT Cells
    Arne Sattler, Lion Gabriel Thiel, Annkathrin Helena Ruhm, Naima Souidi, Martina Seifert, Gunda Herberth and Katja Kotsch
    The Journal of Immunology December 1, 2019, 203 (11) 2970-2978; DOI: https://doi.org/10.4049/jimmunol.1900465
  • Open Access
    Long-Term Microgliosis Driven by Acute Systemic Inflammation
    Alissa Trzeciak, Yelena V. Lerman, Tae-Hyoun Kim, Ma Rie Kim, Nguyen Mai, Marc W. Halterman and Minsoo Kim
    The Journal of Immunology December 1, 2019, 203 (11) 2979-2989; DOI: https://doi.org/10.4049/jimmunol.1900317
  • Open Access
    Glycogen Synthase Kinase 3β Regulates Antiviral Responses of TLR3 via TRAF2–Src Axis
    Ryeojin Ko, Hana Park, Nawon Lee, Jeongin Seo, Woojin Jeong and Soo Young Lee
    The Journal of Immunology December 1, 2019, 203 (11) 2990-2999; DOI: https://doi.org/10.4049/jimmunol.1900685
  • Open Access
    A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to Pseudomonas aeruginosa Lung Infection in Mice
    Chhinder P. Sodhi, Jenny Nguyen, Yukihiro Yamaguchi, Adam D. Werts, Peng Lu, Mitchell R. Ladd, William B. Fulton, Mark L. Kovler, Sanxia Wang, Thomas Prindle Jr., Yong Zhang, Eric D. Lazartigues, Michael J. Holtzman, John F. Alcorn, David J. Hackam and Hongpeng Jia
    The Journal of Immunology December 1, 2019, 203 (11) 3000-3012; DOI: https://doi.org/10.4049/jimmunol.1900579
  • Open Access
    Exercise Promotes Resolution of Acute Inflammation by Catecholamine-Mediated Stimulation of Resolvin D1 Biosynthesis
    Jing-Juan Zheng, Ernesto Pena Calderin, Bradford G. Hill, Aruni Bhatnagar and Jason Hellmann
    The Journal of Immunology December 1, 2019, 203 (11) 3013-3022; DOI: https://doi.org/10.4049/jimmunol.1900144

MOLECULAR AND STRUCTURAL IMMUNOLOGY

  • Open Access
    Ubc9 Interacts with and SUMOylates the TCR Adaptor SLP-76 for NFAT Transcription in T Cells
    Yiwei Xiong, Yulan Yi, Yan Wang, Naiqi Yang, Christopher E. Rudd and Hebin Liu
    The Journal of Immunology December 1, 2019, 203 (11) 3023-3036; DOI: https://doi.org/10.4049/jimmunol.1900556
  • Open Access
    Recognition of Lewis X by Anti-Lex Monoclonal Antibody IG5F6
    Sinthuja Jegatheeswaran and France-Isabelle Auzanneau
    The Journal of Immunology December 1, 2019, 203 (11) 3037-3044; DOI: https://doi.org/10.4049/jimmunol.1900806

MUCOSAL IMMUNOLOGY

  • Open Access
    Uhrf1-Mediated Tnf-α Gene Methylation Controls Proinflammatory Macrophages in Experimental Colitis Resembling Inflammatory Bowel Disease
    Shanshan Qi, Yongkui Li, Zheng Dai, Mengxi Xiang, Guobin Wang, Lin Wang and Zheng Wang
    The Journal of Immunology December 1, 2019, 203 (11) 3045-3053; DOI: https://doi.org/10.4049/jimmunol.1900467
  • Open Access
    Pharyngeal Immunity in Early Vertebrates Provides Functional and Evolutionary Insight into Mucosal Homeostasis
    Wei-guang Kong, Yong-yao Yu, Shuai Dong, Zhen-yu Huang, Li-guo Ding, Jia-feng Cao, Fen Dong, Xiao-ting Zhang, Xia Liu, Hao-yue Xu, Kai-feng Meng, Jian-guo Su and Zhen Xu
    The Journal of Immunology December 1, 2019, 203 (11) 3054-3067; DOI: https://doi.org/10.4049/jimmunol.1900863
  • Open Access
    Dendritic Cells Control Regulatory T Cell Function Required for Maintenance of Intestinal Tissue Homeostasis
    Cornelia Hilpert, Selina Sitte, Harald Arnold, Christian H. K. Lehmann, Diana Dudziak, Jochen Mattner and David Voehringer
    The Journal of Immunology December 1, 2019, 203 (11) 3068-3077; DOI: https://doi.org/10.4049/jimmunol.1900320

TUMOR IMMUNOLOGY

  • Open Access
    STAT3-Induced Wnt5a Provides Chronic Lymphocytic Leukemia Cells with Survival Advantage
    Uri Rozovski, David M. Harris, Ping Li, Zhiming Liu, Preetesh Jain, Alessandra Ferrajoli, Jan A. Burger, Prithviraj Bose, Phillip A. Thompson, Nitin Jain, William G. Wierda, Orit Uziel, Michael J. Keating and Zeev Estrov
    The Journal of Immunology December 1, 2019, 203 (11) 3078-3085; DOI: https://doi.org/10.4049/jimmunol.1900389
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This Issue

The Journal of Immunology: 203 (11)
The Journal of Immunology
Vol. 203, Issue 11
1 Dec 2019
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)

Issue highlights

  • Top Reads
  • Inflammasomes: Their Role in Normal and Complicated Pregnancies
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  • TOP READS
  • TRANSLATING IMMUNOLOGY
  • BRIEF REVIEWS
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
  • AUTOIMMUNITY
  • IMMUNE REGULATION
  • IMMUNE SYSTEM DEVELOPMENT
  • IMMUNOGENETICS
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • MUCOSAL IMMUNOLOGY
  • TUMOR IMMUNOLOGY
  • Highlights
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CCR2-Mediated Uptake of Constitutively Produced CCL2: A Mechanism for Regulating Chemokine Levels in the Blood
Efficient CRISPR/Cas9 Disruption of Autoimmune-Associated Genes Reveals Key Signaling Programs in Primary Human T Cells
CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential
The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection
Chronic Ethanol Consumption Reduces Existing CD8 T Cell Memory and Is Associated with Lesions in Protection against Secondary Influenza A Virus Infections
A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins
Comment on “Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway”
Response to Comment on “Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway”
Comment on “IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells”
Response to Comment on “IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells”

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