On the cover: Micro-computed tomography image of tibia from a mouse given a subtherapeutic dose of anti-TNF Ab to treat collagen-induced arthritis (model of human rheumatoid arthritis), showing only partial alleviation of bone surface roughness. Shen, F., A. H. Verma, A. Volk, B. Jones, B. M. Coleman, M. J. Loza, R. Malaviya, B. Moore, D. Weinstock, M. M. Elloso, S. L. Gaffen, and T. Ort. 2019. Combined blockade of TNF-α and IL-17A alleviates progression of collagen-induced arthritis without causing serious infections in mice. J. Immunol. 202: 2017–2026.