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History
- Received August 22, 2017
- Accepted February 22, 2018
- Published online April 23, 2018.
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- Older version (March 23, 2018 - 08:02).
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Copyright © 2018 by The American Association of Immunologists, Inc.
Author Information
- Emily F. McNaughton*,
- Andrew D. Eustace*,
- Sophie King*,
- Richard B. Sessions†,
- Alasdair Kay‡,
- Michele Farris§,
- Robert Broadbridge§,
- Oksana Kehoe‡,
- Andreas J. Kungl¶ and
- Jim Middleton*
- *School of Oral and Dental Sciences, Faculty of Health Sciences, University of Bristol, Bristol BS1 2LY, United Kingdom;
- †School of Biochemistry, Faculty of Biomedical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom;
- ‡Leopold Muller Arthritis Research Centre, Institute for Science and Technology in Medicine, Robert Jones and Agnes Hunt Orthopaedic Hospital, Medical School, Keele University, Keele SY10 7AG, United Kingdom;
- §Peptide Protein Research Ltd., Bishop's Waltham SO32 1QD, United Kingdom; and
- ¶Karl-Franzens University, Graz 8010, Austria
- Address correspondence and reprint requests to Prof. Jim Middleton, School of Oral and Dental Sciences, Faculty of Health Sciences, University of Bristol, Bristol BS1 2LY, U.K. E-mail address: jim.middleton{at}bristol.ac.uk
J.M. conceived and designed the study. E.F.M., A.D.E., S.K., O.K., and A.K. performed experiments and analyzed data. R.B.S. assisted with peptide modeling and design. M.F. and R.B. provided peptide synthesis facilities and peptide chemistry consultation. A.J.K. advised and contributed to isothermal fluorescent titration data by providing facilities at Karl-Franzens University. E.F.M. and J.M. wrote the manuscript.