On the cover: Nbeal2 is an important structural protein which regulates the protein levels of transcription factors and cell-cycle inhibitors in mast cells. Therefore, Nbeal2 regulates compartmentalization, proliferation, and cytokine production in mast cells. This demonstrates the relevance of Nbeal2 in immunity above and beyond granule biosynthesis. Drube, S., R. Grimlowski, C. Deppermann, J. Fröbel, F. Kraft, N. Andreas, D. Stegner, J. Dudeck, F. Weber, M. Rödiger, C. Göpfert, J. Drube, D. Reich, B. Nieswandt, A. Dudeck, and T. Kamradt. 2017. The neurobeachin-like 2 protein regulates mast cell homeostasis. J. Immunol. 199: 2948–2957.