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The Journal of Immunology

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Table of Contents

August 1, 2017; Volume 199,Issue 3

IN THIS ISSUE

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    In This Issue

    Reducing Immunotherapy-Associated Autoimmunity See article p. 974

    High Salt Diets Exacerbate IBD See article p. 1051

    Teasing Apart Tcrb Transcription See article p. 1131

    Early Secondhand Smoke Exposure Worsens Lung Disorders See article p. 1170

    J Immunol August 1, 2017, 199 (3) 829-830; DOI: https://doi.org/10.4049/jimmunol.1790011

PILLARS OF IMMUNOLOGY

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    Defining the Kinetics, Phenotype, and Function of T Cells Induced by Mycobacterium tuberculosis: Pillar of Immunity to Tuberculosis
    Andrea M. Cooper
    J Immunol August 1, 2017, 199 (3) 831-832; DOI: https://doi.org/10.4049/jimmunol.1700854
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    Pillars Article: The Kinetics of Emergence and Loss of Mediator T Lymphocytes Acquired in Response to Infection with Mycobacterium Tuberculosis. J. Immunol. 1987. 138: 293–298
    Ian M. Orme
    J Immunol August 1, 2017, 199 (3) 833-838;

BRIEF REVIEWS

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    Here, There, and Anywhere? Arguments for and against the Physical Plasma Cell Survival Niche
    Joel R. Wilmore and David Allman
    J Immunol August 1, 2017, 199 (3) 839-845; DOI: https://doi.org/10.4049/jimmunol.1700461

CUTTING EDGE

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    Cutting Edge: Eosinophils Undergo Caspase-1–Mediated Pyroptosis in Response to Necrotic Liver Cells
    Daphne Palacios-Macapagal, Jane Connor, Tomas Mustelin, Thirumalai R. Ramalingam, Thomas A. Wynn and Todd S. Davidson
    J Immunol August 1, 2017, 199 (3) 847-853; DOI: https://doi.org/10.4049/jimmunol.1601162

ALLERGY AND OTHER HYPERSENSITIVITIES

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    Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of Allergen
    John T. Schroeder and Anja P. Bieneman
    J Immunol August 1, 2017, 199 (3) 855-865; DOI: https://doi.org/10.4049/jimmunol.1700055
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    TGF-β1 Suppresses IL-33–Induced Mast Cell Function
    Victor S. Ndaw, Daniel Abebayehu, Andrew J. Spence, Patrick A. Paez, E. Motunrayo Kolawole, Marcela T. Taruselli, Heather L. Caslin, Alena P. Chumanevich, Anuya Paranjape, Bianca Baker, Brian O. Barnstein, Tamara T. Haque, Kasalina N. Kiwanuka, Carole A. Oskeritzian and John J. Ryan
    J Immunol August 1, 2017, 199 (3) 866-873; DOI: https://doi.org/10.4049/jimmunol.1601983

ANTIGEN RECOGNITION AND RESPONSES

  • Open Access
    Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

    Author Choice Article

    Jessica G. Borger, Vicky L. Morrison, Andrew Filby, Celine Garcia, Liisa M. Uotila, Fabio Simbari, Susanna C. Fagerholm and Rose Zamoyska
    J Immunol August 1, 2017, 199 (3) 874-884; DOI: https://doi.org/10.4049/jimmunol.1700431
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    B Cell–Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B Cell Immune Responses
    Rebecca A. Sweet, Kevin M. Nickerson, Jaime L. Cullen, Yujuan Wang and Mark J. Shlomchik
    J Immunol August 1, 2017, 199 (3) 885-893; DOI: https://doi.org/10.4049/jimmunol.1600861

AUTOIMMUNITY

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    On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes
    Tobechukwu K. Ukah, Alexis N. Cattin-Roy, Weirong Chen, Mindy M. Miller, Subhasis Barik and Habib Zaghouani
    J Immunol August 1, 2017, 199 (3) 894-902; DOI: https://doi.org/10.4049/jimmunol.1700410

CLINICAL AND HUMAN IMMUNOLOGY

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    IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus
    Hong Dai, Fan He, George C. Tsokos and Vasileios C. Kyttaris
    J Immunol August 1, 2017, 199 (3) 903-910; DOI: https://doi.org/10.4049/jimmunol.1700418

IMMUNE REGULATION

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    Differential Requirements for Tcf1 Long Isoforms in CD8+ and CD4+ T Cell Responses to Acute Viral Infection
    Jodi A. Gullicksrud, Fengyin Li, Shaojun Xing, Zhouhao Zeng, Weiqun Peng, Vladimir P. Badovinac, John T. Harty and Hai-Hui Xue
    J Immunol August 1, 2017, 199 (3) 911-919; DOI: https://doi.org/10.4049/jimmunol.1700595
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    c-REL and IκBNS Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors
    Marc Schuster, Carlos Plaza-Sirvent, Anne-Marie Matthies, Ulrike Heise, Andreas Jeron, Dunja Bruder, Alexander Visekruna, Jochen Huehn and Ingo Schmitz
    J Immunol August 1, 2017, 199 (3) 920-930; DOI: https://doi.org/10.4049/jimmunol.1600877
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    B Cells Produce Type 1 IFNs in Response to the TLR9 Agonist CpG-A Conjugated to Cationic Lipids
    Munir Akkaya, Billur Akkaya, Pietro Miozzo, Mukul Rawat, Mirna Pena, Patrick W. Sheehan, Ann S. Kim, Olena Kamenyeva, Juraj Kabat, Silvia Bolland, Akanksha Chaturvedi and Susan K. Pierce
    J Immunol August 1, 2017, 199 (3) 931-940; DOI: https://doi.org/10.4049/jimmunol.1700348
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    TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy
    Jian Ye, Yadan Wang, Xia Liu, Lingyun Li, Adeleye Opejin, Eddy C. Hsueh, Huanle Luo, Tian Wang, Daniel Hawiger and Guangyong Peng
    J Immunol August 1, 2017, 199 (3) 941-954; DOI: https://doi.org/10.4049/jimmunol.1601890
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    Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt
    Zhiheng He, Fei Wang, Jing Zhang, Subha Sen, Qihua Pang, Shengwei Luo, Yousang Gwack and Zuoming Sun
    J Immunol August 1, 2017, 199 (3) 955-964; DOI: https://doi.org/10.4049/jimmunol.1700457

IMMUNE SYSTEM DEVELOPMENT

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    Alterations in the Thymic Selection Threshold Skew the Self-Reactivity of the TCR Repertoire in Neonates
    Mengqi Dong, Patricio Artusa, Stephanie A. Kelly, Marilaine Fournier, Troy A. Baldwin, Judith N. Mandl and Heather J. Melichar
    J Immunol August 1, 2017, 199 (3) 965-973; DOI: https://doi.org/10.4049/jimmunol.1602137

IMMUNOTHERAPY AND VACCINES

  • Open Access
    Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity

    Author Choice Article

    Maher G. Nawaf, Maria H. Ulvmar, David R. Withers, Fiona M. McConnell, Fabrina M. Gaspal, Gwilym J. Webb, Nick D. Jones, Hideo Yagita, James P. Allison and Peter J. L. Lane
    J Immunol August 1, 2017, 199 (3) 974-981; DOI: https://doi.org/10.4049/jimmunol.1700088

INFECTIOUS DISEASE AND HOST RESPONSE

  • Open Access
    Monocyte Adhesion, Migration, and Extracellular Matrix Breakdown Are Regulated by Integrin αVβ3 in Mycobacterium tuberculosis Infection

    Author Choice Article

    Sara Brilha, Riccardo Wysoczanski, Ashley M. Whittington, Jon S. Friedland and Joanna C. Porter
    J Immunol August 1, 2017, 199 (3) 982-991; DOI: https://doi.org/10.4049/jimmunol.1700128
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    Wnt5a Signaling Promotes Host Defense against Leishmania donovani Infection
    Arijit Chakraborty, Sony Priya Kurati, Sushil K. Mahata, Shyam Sundar, Syamal Roy and Malini Sen
    J Immunol August 1, 2017, 199 (3) 992-1002; DOI: https://doi.org/10.4049/jimmunol.1601927
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    Immune Cell Dynamics in Rhesus Macaques Infected with a Brazilian Strain of Zika Virus
    Eduardo L. V. Silveira, Kenneth A. Rogers, Sanjeev Gumber, Praveen Amancha, Peng Xiao, Shawna M. Woollard, Siddappa N. Byrareddy, Mauro Martins Teixeira and Francois Villinger
    J Immunol August 1, 2017, 199 (3) 1003-1011; DOI: https://doi.org/10.4049/jimmunol.1700256

INNATE IMMUNITY AND INFLAMMATION

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    Involvement of NK Cells in IL-28B–Mediated Immunity against Influenza Virus Infection
    Yanshi Wang, Tingting Li, Yongyan Chen, Haiming Wei, Rui Sun and Zhigang Tian
    J Immunol August 1, 2017, 199 (3) 1012-1020; DOI: https://doi.org/10.4049/jimmunol.1601430
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    Interaction between Multimeric von Willebrand Factor and Complement: A Fresh Look to the Pathophysiology of Microvascular Thrombosis
    Serena Bettoni, Miriam Galbusera, Sara Gastoldi, Roberta Donadelli, Chiara Tentori, Giuseppina Spartà, Elena Bresin, Caterina Mele, Marta Alberti, Agustin Tortajada, Hugo Yebenes, Giuseppe Remuzzi and Marina Noris
    J Immunol August 1, 2017, 199 (3) 1021-1040; DOI: https://doi.org/10.4049/jimmunol.1601121
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    Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice
    David R. Gibb, Jingchun Liu, Prabitha Natarajan, Manjula Santhanakrishnan, David J. Madrid, Stephanie C. Eisenbarth, James C. Zimring, Akiko Iwasaki and Jeanne E. Hendrickson
    J Immunol August 1, 2017, 199 (3) 1041-1050; DOI: https://doi.org/10.4049/jimmunol.1700401
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    Dietary Salt Exacerbates Experimental Colitis
    Alan L. Tubbs, Bo Liu, Troy D. Rogers, R. Balfour Sartor and Edward A. Miao
    J Immunol August 1, 2017, 199 (3) 1051-1059; DOI: https://doi.org/10.4049/jimmunol.1700356
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    Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice
    Christine K. Wong, Candice A. Smith, Koji Sakamoto, Naftali Kaminski, Jonathan L. Koff and Daniel R. Goldstein
    J Immunol August 1, 2017, 199 (3) 1060-1068; DOI: https://doi.org/10.4049/jimmunol.1700397
  • Open Access
    Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis

    Author Choice Article

    Mitra J. Hooshmand, Hal X. Nguyen, Katja M. Piltti, Francisca Benavente, Samuel Hong, Lisa Flanagan, Nobuko Uchida, Brian J. Cummings and Aileen J. Anderson
    J Immunol August 1, 2017, 199 (3) 1069-1085; DOI: https://doi.org/10.4049/jimmunol.1600064
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    Deficiency of Phosphatidylinositol 3-Kinase δ Signaling Leads to Diminished Numbers of Regulatory T Cells and Increased Neutrophil Activity Resulting in Mortality Due to Endotoxic Shock
    Emeka B. Okeke, Zhirong Mou, Nonso Onyilagha, Ping Jia, Abdelilah S. Gounni and Jude E. Uzonna
    J Immunol August 1, 2017, 199 (3) 1086-1095; DOI: https://doi.org/10.4049/jimmunol.1600954
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    Leukotriene C4 Potentiates IL-33–Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation
    Sean J. Lund, Alex Portillo, Kellen Cavagnero, Rachel E. Baum, Luay H. Naji, Jana H. Badrani, Amit Mehta, Michael Croft, David H. Broide and Taylor A. Doherty
    J Immunol August 1, 2017, 199 (3) 1096-1104; DOI: https://doi.org/10.4049/jimmunol.1601569
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    Suppression of Lipopolysaccharide-Induced Inflammatory Response by Fragments from Serum Amyloid A
    Huibin Zhou, Mingjie Chen, Gufang Zhang and Richard D. Ye
    J Immunol August 1, 2017, 199 (3) 1105-1112; DOI: https://doi.org/10.4049/jimmunol.1700470
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    Activation of Complement by Pigment Epithelium–Derived Factor in Rheumatoid Arthritis
    Leonie M. Vogt, Simone Talens, Ewa Kwasniewicz, Carsten Scavenius, André Struglics, Jan J. Enghild, Tore Saxne and Anna M. Blom
    J Immunol August 1, 2017, 199 (3) 1113-1121; DOI: https://doi.org/10.4049/jimmunol.1700018
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    Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo
    Ryosuke Uchiyama, Shin Yonehara, Shun’ichiro Taniguchi, Satoshi Ishido, Ken J. Ishii and Hiroko Tsutsui
    J Immunol August 1, 2017, 199 (3) 1122-1130; DOI: https://doi.org/10.4049/jimmunol.1601373

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Activation of Mouse Tcrb: Uncoupling RUNX1 Function from Its Cooperative Binding with ETS1
    Jiang-yang Zhao, Oleg Osipovich, Olivia I. Koues, Kinjal Majumder and Eugene M. Oltz
    J Immunol August 1, 2017, 199 (3) 1131-1141; DOI: https://doi.org/10.4049/jimmunol.1700146
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    Structural and Mechanistic Implications of Rearrangement Frequencies within Human TCRBV Genes
    Maryam B. Yassai, Wendy Demos and Jack Gorski
    J Immunol August 1, 2017, 199 (3) 1142-1152; DOI: https://doi.org/10.4049/jimmunol.1601450
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    Menin Controls the Memory Th2 Cell Function by Maintaining the Epigenetic Integrity of Th2 Cells
    Atsushi Onodera, Masahiro Kiuchi, Kota Kokubo, Miki Kato, Tomohiro Ogino, Shu Horiuchi, Urara Kanai, Kiyoshi Hirahara and Toshinori Nakayama
    J Immunol August 1, 2017, 199 (3) 1153-1162; DOI: https://doi.org/10.4049/jimmunol.1602129

MUCOSAL IMMUNOLOGY

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    IFN-γ–Expressing Th17 Cells Are Required for Development of Severe Ocular Surface Autoimmunity
    Yihe Chen, Sunil K. Chauhan, Chunyi Shao, Masahiro Omoto, Takenori Inomata and Reza Dana
    J Immunol August 1, 2017, 199 (3) 1163-1169; DOI: https://doi.org/10.4049/jimmunol.1602144
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    Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease
    Brandon W. Lewis, Razia Sultana, Rahul Sharma, Alexandra Noël, Ingeborg Langohr, Sonika Patial, Arthur L. Penn and Yogesh Saini
    J Immunol August 1, 2017, 199 (3) 1170-1183; DOI: https://doi.org/10.4049/jimmunol.1700144
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    CD36 and Platelet-Activating Factor Receptor Promote House Dust Mite Allergy Development
    Preeyam S. Patel and John F. Kearney
    J Immunol August 1, 2017, 199 (3) 1184-1195; DOI: https://doi.org/10.4049/jimmunol.1700034

TRANSPLANTATION

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    Lack of Both Nucleotide-Binding Oligomerization Domain–Containing Proteins 1 and 2 Primes T Cells for Activation-Induced Cell Death
    Sashi G. Kasimsetty, Alana A. Shigeoka, Andrew A. Scheinok, Amanda L. Gavin, Richard J. Ulevitch and Dianne B. McKay
    J Immunol August 1, 2017, 199 (3) 1196-1205; DOI: https://doi.org/10.4049/jimmunol.1600667

LETTERS OF RETRACTION

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    Retraction: Hypoxia-Inducible Factor (HIF) 1α Accumulation and HIF Target Gene Expression Are Impaired after Induction of Endotoxin Tolerance
    Stilla Frede, Christian Stockmann, Sandra Winning, Patricia Freitag and Joachim Fandrey
    J Immunol August 1, 2017, 199 (3) 1206; DOI: https://doi.org/10.4049/jimmunol.1700863

CORRECTIONS

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    Correction: DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia
    Yan Ye, Ping Lin, Weidong Zhang, Shirui Tan, Xikun Zhou, Rongpeng Li, Qinqin Pu, Jonathan L. Koff, Archana Dhasarathy, Feng Ma, Xin Deng, Jianxin Jiang and Min Wu
    J Immunol August 1, 2017, 199 (3) 1207; DOI: https://doi.org/10.4049/jimmunol.1700711
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This Issue

The Journal of Immunology: 199 (3)
The Journal of Immunology
Vol. 199, Issue 3
1 Aug 2017
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)

Issue highlights

  • In This Issue
  • Here, There, and Anywhere? Arguments for and against the Physical Plasma Cell Survival Niche
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  • IN THIS ISSUE
  • PILLARS OF IMMUNOLOGY
  • BRIEF REVIEWS
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
  • ANTIGEN RECOGNITION AND RESPONSES
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNE SYSTEM DEVELOPMENT
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • MUCOSAL IMMUNOLOGY
  • TRANSPLANTATION
  • LETTERS OF RETRACTION
  • CORRECTIONS
  • Highlights
  • Most Cited
  • Most Read
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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